Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Arnaldur Hall"'
Autor:
Lin-Ping Wu, Davoud Ahmadvand, Junan Su, Arnaldur Hall, Xiaolong Tan, Z. Shadi Farhangrazi, S. Moein Moghimi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Bacteriophages can bind targets with only a few copies of a display peptide while most nanoparticles with thousands achieve poor binding. Here the authors form hierarchical arrangements of phage peptides to delivery siRNA across the blood brain barri
Externí odkaz:
https://doaj.org/article/9def93cd838b4e7488bbdf9487ba930d
Autor:
Scott Maynard, Arnaldur Hall, Panagiotis Galanos, Salvatore Rizza, Tatsuro Yamamoto, Helena Hagner Gram, Sebastian H N Munk, Muhammad Shoaib, Claus Storgaard Sørensen, Vilhelm A Bohr, Mads Lerdrup, Apolinar Maya-Mendoza, Jiri Bartek
Publikováno v:
Maynard, S, Hall, A, Galanos, P, Rizza, S, Yamamoto, T, Gram, H H, Munk, S H N, Shoaib, M, Sørensen, C S, Bohr, V A, Lerdrup, M, Maya-Mendoza, A & Bartek, J 2022, ' Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1 and the NAMPT-NAD + pathway ', Nucleic Acids Research, vol. 50, no. 17, pp. 9948-9965 . https://doi.org/10.1093/nar/gkac741
Mutations in the lamin A/C gene (LMNA) cause laminopathies such as the premature aging Hutchinson Gilford progeria syndrome (HGPS) and altered lamin A/C levels are found in diverse malignancies. The underlying lamin-associated mechanisms remain poorl
Autor:
Jiri Bartek, Arnaldur Hall, Lin-Ping Wu, Robert Strauss, Joanna Maria Merchut-Maya, Seyed Moein Moghimi, Scott Maynard
Publikováno v:
Journal of Controlled Release. 309:158-172
Acquired resistance to the oncogenic BRAFE600 inhibitor vemurafenib is a major clinical challenge in the treatment of melanoma. Vemurafenib resistance is poorly understood; however, available evidence indicates that reprogrammed mitochondrial metabol
Autor:
Arnaldur Hall, Morten Scheibye-Knudsen, Scott Maynard, Mansour Akbari, Marya Morevati, Guido Keijzers, Susana Gonzalo, Michael Ben Ezra, Vilhelm A. Bohr, Jiri Bartek
Publikováno v:
Nucleic acids research. 47(22)
The A-type lamins (lamin A/C), encoded by the LMNA gene, are important structural components of the nuclear lamina. LMNA mutations lead to degenerative disorders known as laminopathies, including the premature aging disease Hutchinson-Gilford progeri
Autor:
Arnaldur, Hall, Scott, Maynard, Lin-Ping, Wu, Joanna Maria, Merchut-Maya, Robert, Strauss, Seyed Moein, Moghimi, Jiri, Bartek
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 309
Acquired resistance to the oncogenic BRAF
Autor:
Arnaldur, Hall, S Moein, Moghimi
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1943
A better understanding of the molecular basis of polycation-mediated impairment of mitochondrial bioenergetics might improve the design and synthesis of more efficient and safer polymeric transfectants. Here we utilize the phosphorylation control pro
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1943
Cationic polyplexes and lipoplexes are widely used as artificial systems for nucleic acid delivery into the cells, but they can also induce cell death. Mechanistic understanding of cell toxicity and biological side effects of these cationic entities
Autor:
Marja Jäättelä, Jirina Bartkova, Jan Bouchal, Riccardo Vanzo, Arnaldur Hall, Lars Dyrskjøt, Lisa B. Frankel, Joanna Maria Merchut-Maya, Jiri Bartek, Vassilis G. Gorgoulis, Apolinar Maya-Mendoza
Publikováno v:
Cell Death Differ
Vanzo, R, Bartkova, J, Merchut-Maya, J M, Hall, A, Bouchal, J, Dyrskjøt, L, Frankel, L B, Gorgoulis, V, Maya-Mendoza, A, Jäättelä, M & Bartek, J 2020, ' Autophagy role(s) in response to oncogenes and DNA replication stress ', Cell Death and Differentiation, vol. 27, no. 3, pp. 1134-1153 . https://doi.org/10.1038/s41418-019-0403-9
Cell Death and Differentiation
Vanzo, R, Bartkova, J, Merchut-Maya, J M, Hall, A, Bouchal, J, Dyrskjøt, L, Frankel, L B, Gorgoulis, V, Maya-Mendoza, A, Jäättelä, M & Bartek, J 2020, ' Autophagy role(s) in response to oncogenes and DNA replication stress ', Cell Death & Differentiation, vol. 27, no. 3, pp. 1134-1153 . https://doi.org/10.1038/s41418-019-0403-9
Vanzo, R, Bartkova, J, Merchut-Maya, J M, Hall, A, Bouchal, J, Dyrskjøt, L, Frankel, L B, Gorgoulis, V, Maya-Mendoza, A, Jäättelä, M & Bartek, J 2020, ' Autophagy role(s) in response to oncogenes and DNA replication stress ', Cell Death and Differentiation, vol. 27, no. 3, pp. 1134-1153 . https://doi.org/10.1038/s41418-019-0403-9
Cell Death and Differentiation
Vanzo, R, Bartkova, J, Merchut-Maya, J M, Hall, A, Bouchal, J, Dyrskjøt, L, Frankel, L B, Gorgoulis, V, Maya-Mendoza, A, Jäättelä, M & Bartek, J 2020, ' Autophagy role(s) in response to oncogenes and DNA replication stress ', Cell Death & Differentiation, vol. 27, no. 3, pp. 1134-1153 . https://doi.org/10.1038/s41418-019-0403-9
Autophagy is an evolutionarily conserved process that captures aberrant intracellular proteins and/or damaged organelles for delivery to lysosomes, with implications for cellular and organismal homeostasis, aging and diverse pathologies, including ca
Publikováno v:
Nanotechnology for Nucleic Acid Delivery ISBN: 9781493990917
Nanotechnology for Nucleic Acid Delivery ISBN: 9781627031394
Nanotechnology for Nucleic Acid Delivery ISBN: 9781627031394
Cationic polyplexes and lipoplexes are widely used as artificial systems for nucleic acid delivery into the cells, but they can also induce cell death. Mechanistic understanding of cell toxicity and biological side effects of these cationic entities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c011fff8150a7e1aa40d6c7cf4048d4d
https://doi.org/10.1007/978-1-4939-9092-4_19
https://doi.org/10.1007/978-1-4939-9092-4_19
Autor:
Arnaldur Hall, S. Moein Moghimi
Publikováno v:
Nanotechnology for Nucleic Acid Delivery ISBN: 9781493990917
A better understanding of the molecular basis of polycation-mediated impairment of mitochondrial bioenergetics might improve the design and synthesis of more efficient and safer polymeric transfectants. Here we utilize the phosphorylation control pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f03a8dabdcac0152b878f9bf89cddcf
https://doi.org/10.1007/978-1-4939-9092-4_20
https://doi.org/10.1007/978-1-4939-9092-4_20