Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Arnab Ray, Chaudhuri"'
Autor:
Ramona N. Moro, Uddipta Biswas, Suhas S. Kharat, Filip D. Duzanic, Prosun Das, Maria Stavrou, Maria C. Raso, Raimundo Freire, Arnab Ray Chaudhuri, Shyam K. Sharan, Lorenza Penengo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract DNA replication and repair defects or genotoxic treatments trigger interferon (IFN)-mediated inflammatory responses. However, whether and how IFN signaling in turn impacts the DNA replication process has remained elusive. Here we show that b
Externí odkaz:
https://doaj.org/article/64183fd52790466eb0edc4131fa2fe97
Autor:
Anne Margriet Heijink, Colin Stok, David Porubsky, Eleni Maria Manolika, Jurrian K. de Kanter, Yannick P. Kok, Marieke Everts, H. Rudolf de Boer, Anastasia Audrey, Femke J. Bakker, Elles Wierenga, Marcel Tijsterman, Victor Guryev, Diana C. J. Spierings, Puck Knipscheer, Ruben van Boxtel, Arnab Ray Chaudhuri, Peter M. Lansdorp, Marcel A. T. M. van Vugt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Sister chromatid exchanges (SCEs) are considered to be products of homologous recombination repair. The authors show that SCEs can arise independently of homologous recombination due to processing of replication intermediates during mitosis.
Externí odkaz:
https://doaj.org/article/6a7ed7595d2b4f12a042a1aaa930abc6
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/409715e2636d409f807daa6ab27b7bba
Autor:
Chirantani Mukherjee, Vivek Tripathi, Eleni Maria Manolika, Anne Margriet Heijink, Giulia Ricci, Sarra Merzouk, H. Rudolf de Boer, Jeroen Demmers, Marcel A. T. M. van Vugt, Arnab Ray Chaudhuri
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Replication fork degradation can result in genome instability. Here authors reveal a role for Rif1 protein in protecting stalled replication forks from undergoing extensive, DNA2-dependent, degradation.
Externí odkaz:
https://doaj.org/article/cb070f743a7d4af79f8d12d89e2dfee4
Autor:
Sofija Mijic, Ralph Zellweger, Nagaraja Chappidi, Matteo Berti, Kurt Jacobs, Karun Mutreja, Sebastian Ursich, Arnab Ray Chaudhuri, Andre Nussenzweig, Pavel Janscak, Massimo Lopes
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
BRCA2 is involved in both homologous recombination (HR) and the protection of stalled replication forks from degradation. Here the authors reveal how HR factors cooperate in fork remodeling, showing that BRCA2 supports RAD51 loading on the regressed
Externí odkaz:
https://doaj.org/article/37f10f169bf74902a273599741eefa33
Autor:
Alice Meroni, Sophie E. Wells, Carmen Fonseca, Arnab Ray Chaudhuri, Keith W. Caldecott, Alessandro Vindigni
Publikováno v:
bioRxiv
SummaryDNA combing and DNA spreading are two central approaches for studying DNA replication fork dynamics genome-wide at single-molecule resolution by distributing labeled genomic DNA on coverslips or slides for immunodetection. Perturbations in DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0f838238ce33f4239c3fbdd36c7df2
https://doi.org/10.1101/2023.05.02.539129
https://doi.org/10.1101/2023.05.02.539129
Autor:
Xia Ding, Arnab Ray Chaudhuri, Elsa Callen, Yan Pang, Kajal Biswas, Kimberly D. Klarmann, Betty K. Martin, Sandra Burkett, Linda Cleveland, Stacey Stauffer, Teresa Sullivan, Aashish Dewan, Hanna Marks, Anthony T. Tubbs, Nancy Wong, Eugen Buehler, Keiko Akagi, Scott E. Martin, Jonathan R. Keller, André Nussenzweig, Shyam K. Sharan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The PARP inhibitor olaparib is an approved treatment method for women with BRCA1 and BRCA2 mutation associated cancers. Here the authors show that olaparib can contribute to synthetic viability of cells if PARP1 is inhibited before BRCA2 loss.
Externí odkaz:
https://doaj.org/article/cf505f822a744ac9ab12008610c61b55
Autor:
Biswanath Maity, Adele Stewart, Sujoy Ghosh, Madhusudan Das, Arnab Ray Chaudhuri, Somnath Singha Roy, Sudipta Saha, Arnab Pramanick, Sreemoyee Chakraborti
Figure S3. Gβ5 promotes chemotherapeutic drug-induced oxidative stress in isolated VCM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657f8e9a7ae721ec07a4302afb022864
https://doi.org/10.1158/0008-5472.22418150.v1
https://doi.org/10.1158/0008-5472.22418150.v1
Autor:
Biswanath Maity, Adele Stewart, Sujoy Ghosh, Madhusudan Das, Arnab Ray Chaudhuri, Somnath Singha Roy, Sudipta Saha, Arnab Pramanick, Sreemoyee Chakraborti
Figure S4. Gβ5 knockdown obviates mobilization of antioxidant defense systems in VCM exposed to chemotherapeutic drugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e25bdd5d7eb0e0ab3f0f11849335043
https://doi.org/10.1158/0008-5472.22418147.v1
https://doi.org/10.1158/0008-5472.22418147.v1
Autor:
Biswanath Maity, Adele Stewart, Sujoy Ghosh, Madhusudan Das, Arnab Ray Chaudhuri, Somnath Singha Roy, Sudipta Saha, Arnab Pramanick, Sreemoyee Chakraborti
Figure S1. Gβ5 upregulation following chemotherapeutic drug exposure requires new protein synthesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38ad5d98a3a800033abbc968b246bdb
https://doi.org/10.1158/0008-5472.22418156
https://doi.org/10.1158/0008-5472.22418156