Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Arnab Ray"'
Autor:
Ramona N. Moro, Uddipta Biswas, Suhas S. Kharat, Filip D. Duzanic, Prosun Das, Maria Stavrou, Maria C. Raso, Raimundo Freire, Arnab Ray Chaudhuri, Shyam K. Sharan, Lorenza Penengo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract DNA replication and repair defects or genotoxic treatments trigger interferon (IFN)-mediated inflammatory responses. However, whether and how IFN signaling in turn impacts the DNA replication process has remained elusive. Here we show that b
Externí odkaz:
https://doaj.org/article/64183fd52790466eb0edc4131fa2fe97
Autor:
Anne Margriet Heijink, Colin Stok, David Porubsky, Eleni Maria Manolika, Jurrian K. de Kanter, Yannick P. Kok, Marieke Everts, H. Rudolf de Boer, Anastasia Audrey, Femke J. Bakker, Elles Wierenga, Marcel Tijsterman, Victor Guryev, Diana C. J. Spierings, Puck Knipscheer, Ruben van Boxtel, Arnab Ray Chaudhuri, Peter M. Lansdorp, Marcel A. T. M. van Vugt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Sister chromatid exchanges (SCEs) are considered to be products of homologous recombination repair. The authors show that SCEs can arise independently of homologous recombination due to processing of replication intermediates during mitosis.
Externí odkaz:
https://doaj.org/article/6a7ed7595d2b4f12a042a1aaa930abc6
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/409715e2636d409f807daa6ab27b7bba
Autor:
Chirantani Mukherjee, Vivek Tripathi, Eleni Maria Manolika, Anne Margriet Heijink, Giulia Ricci, Sarra Merzouk, H. Rudolf de Boer, Jeroen Demmers, Marcel A. T. M. van Vugt, Arnab Ray Chaudhuri
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Replication fork degradation can result in genome instability. Here authors reveal a role for Rif1 protein in protecting stalled replication forks from undergoing extensive, DNA2-dependent, degradation.
Externí odkaz:
https://doaj.org/article/cb070f743a7d4af79f8d12d89e2dfee4
Autor:
Yuanjun Shen, Dmitry A. Goncharov, Theodore Avolio, Arnab Ray, Evelyn Okorie, Horace DeLisser, Ana L. Mora, Rebecca Vanderpool, Tatiana V. Kudryashova, Elena A. Goncharova
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Pulmonary arterial hypertension (PAH) is a progressive fatal disease with no cure. Inhibition of integrin-linked kinase (ILK) reverses experimental pulmonary hypertension (PH) in male mice, but its effect on severe experimental PH in either male or f
Externí odkaz:
https://doaj.org/article/4601f709d4114b24a25bb465d5235762
Autor:
Arnab Ray
Publikováno v:
PostScriptum: An Interdisciplinary Journal of Literary Studies, Vol 5, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/378c0b42b8a74c2b9da8feb80bc6d68a
Autor:
Sofija Mijic, Ralph Zellweger, Nagaraja Chappidi, Matteo Berti, Kurt Jacobs, Karun Mutreja, Sebastian Ursich, Arnab Ray Chaudhuri, Andre Nussenzweig, Pavel Janscak, Massimo Lopes
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
BRCA2 is involved in both homologous recombination (HR) and the protection of stalled replication forks from degradation. Here the authors reveal how HR factors cooperate in fork remodeling, showing that BRCA2 supports RAD51 loading on the regressed
Externí odkaz:
https://doaj.org/article/37f10f169bf74902a273599741eefa33
Autor:
Xia Ding, Arnab Ray Chaudhuri, Elsa Callen, Yan Pang, Kajal Biswas, Kimberly D. Klarmann, Betty K. Martin, Sandra Burkett, Linda Cleveland, Stacey Stauffer, Teresa Sullivan, Aashish Dewan, Hanna Marks, Anthony T. Tubbs, Nancy Wong, Eugen Buehler, Keiko Akagi, Scott E. Martin, Jonathan R. Keller, André Nussenzweig, Shyam K. Sharan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The PARP inhibitor olaparib is an approved treatment method for women with BRCA1 and BRCA2 mutation associated cancers. Here the authors show that olaparib can contribute to synthetic viability of cells if PARP1 is inhibited before BRCA2 loss.
Externí odkaz:
https://doaj.org/article/cf505f822a744ac9ab12008610c61b55
Autor:
Arnab Ray Chaudhuri, André Nussenzweig
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 10, Pp 1331-1333 (2017)
Abstract Homologous recombination (HR) and the Fanconi Anemia (FA) pathways constitute essential repair pathways for DNA damage, which includes DNA double‐stranded breaks (DSB) and inter‐strand cross‐links (ICL), respectively. Germline mutation
Externí odkaz:
https://doaj.org/article/d2605246ba4843918008861b183c0399
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