Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Arnab, Pradhan"'
Autor:
Jennie S. Campbell, James C. Pearce, Attila Bebes, Arnab Pradhan, Raif Yuecel, Alistair J P Brown, James G. Wakefield
Publikováno v:
Virulence, Vol 15, Iss 1 (2024)
ABSTRACTOver the last 20 years, the larva of the greater waxmoth, Galleria mellonella, has rapidly increased in popularity as an in vivo mammalian replacement model organism for the study of human pathogens. Experimental readouts of response to infec
Externí odkaz:
https://doaj.org/article/db7bd909eab64159a84e6aa169f0f476
Autor:
Qinxi Ma, Arnab Pradhan, Ian Leaves, Emer Hickey, Elena Roselletti, Ivy Dambuza, Daniel E. Larcombe, Leandro Jose de Assis, Duncan Wilson, Lars P. Erwig, Mihai G. Netea, Delma S. Childers, Gordon D. Brown, Neil A.R. Gow, Alistair J.P. Brown
Publikováno v:
The Cell Surface, Vol 11, Iss , Pp 100128- (2024)
Host recognition of the pathogen-associated molecular pattern (PAMP), β-1,3-glucan, plays a major role in antifungal immunity. β-1,3-glucan is an essential component of the inner cell wall of the opportunistic pathogen Candida albicans. Most β-1,3
Externí odkaz:
https://doaj.org/article/246a9682c09641f7a0a0fda1cc487324
Autor:
Gabriela M. Avelar, Arnab Pradhan, Qinxi Ma, Emer Hickey, Ian Leaves, Corin Liddle, Alejandra V. Rodriguez Rondon, Ann-Kristin Kaune, Sophie Shaw, Corinne Maufrais, Natacha Sertour, Judith M. Bain, Daniel E. Larcombe, Leandro J. de Assis, Mihai G. Netea, Carol A. Munro, Delma S. Childers, Lars P. Erwig, Gordon D. Brown, Neil A. R. Gow, Marie-Elisabeth Bougnoux, Christophe d'Enfert, Alistair J. P. Brown
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Microbial species capable of co-existing with healthy individuals, such as the commensal fungus Candida albicans, exploit multifarious strategies to evade our immune defenses. These strategies include the masking of immunoinflammatory pathog
Externí odkaz:
https://doaj.org/article/a315d65d8db7474e9c59617b6af6132d
Autor:
Leandro José de Assis, Judith M. Bain, Corin Liddle, Ian Leaves, Christian Hacker, Roberta Peres da Silva, Raif Yuecel, Attila Bebes, David Stead, Delma S. Childers, Arnab Pradhan, Kevin Mackenzie, Katherine Lagree, Daniel E. Larcombe, Qinxi Ma, Gabriela Mol Avelar, Mihai G. Netea, Lars P. Erwig, Aaron P. Mitchell, Gordon D. Brown, Neil A. R. Gow, Alistair J. P. Brown
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Candida albicans exists as a commensal of mucosal surfaces and the gastrointestinal tract without causing pathology. However, this fungus is also a common cause of mucosal and systemic infections when antifungal immune defenses become compro
Externí odkaz:
https://doaj.org/article/7eee21d07077458d862a678b6efa049c
Autor:
Gabriela M. Avelar, Ivy M. Dambuza, Liviana Ricci, Raif Yuecel, Kevin Mackenzie, Delma S. Childers, Judith M. Bain, Arnab Pradhan, Daniel E. Larcombe, Mihai G. Netea, Lars P. Erwig, Gordon D. Brown, Sylvia H. Duncan, Neil A.R. Gow, Alan W. Walker, Alistair J.P. Brown
Publikováno v:
The Cell Surface, Vol 8, Iss , Pp 100084- (2022)
The immunogenicity of Candida albicans cells is influenced by changes in the exposure of microbe-associated molecular patterns (MAMPs) on the fungal cell surface. Previously, the degree of exposure on the C. albicans cell surface of the immunoinflamm
Externí odkaz:
https://doaj.org/article/369d68d889004bc9b1d341433c89942b
Autor:
Arnab Pradhan, Gabriela M. Avelar, Judith M. Bain, Delma Childers, Chloe Pelletier, Daniel E. Larcombe, Elena Shekhova, Mihai G. Netea, Gordon D. Brown, Lars Erwig, Neil A. R. Gow, Alistair J. P. Brown
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The authors show that the fungal pathogen Candida albicans exploits diverse host-associated signals, including specific nutrients and stresses, to promote immune evasion by masking cell wall β-glucan, a major pathogen-associated molecular pattern.
Externí odkaz:
https://doaj.org/article/bd3459245a7f49d29f8307da698409ae
Autor:
Remi Hatinguais, Arnab Pradhan, Gordon D. Brown, Alistair J. P. Brown, Adilia Warris, Elena Shekhova
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Reactive Oxygen Species (ROS) are highly reactive molecules that can induce oxidative stress. For instance, the oxidative burst of immune cells is well known for its ability to inhibit the growth of invading pathogens. However, ROS also mediate redox
Externí odkaz:
https://doaj.org/article/d58d2f5f277b4a969e55066468b76c61
Autor:
Delma S. Childers, Gabriela Mol Avelar, Judith M. Bain, Arnab Pradhan, Daniel E. Larcombe, Mihai G. Netea, Lars P. Erwig, Neil A. R. Gow, Alistair J. P. Brown
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT The cell wall provides a major physical interface between fungal pathogens and their mammalian host. This extracellular armor is critical for fungal cell homeostasis and survival. Fungus-specific cell wall moieties, such as β-1,3-glucan, ar
Externí odkaz:
https://doaj.org/article/4da9c9b4bb334467bcbb87a32cd2e4e6
Autor:
Arnab Pradhan, Gabriela M. Avelar, Judith M. Bain, Delma S. Childers, Daniel E. Larcombe, Mihai G. Netea, Elena Shekhova, Carol A. Munro, Gordon D. Brown, Lars P. Erwig, Neil A. R. Gow, Alistair J. P. Brown
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
ABSTRACT Organisms must adapt to changes in oxygen tension if they are to exploit the energetic benefits of reducing oxygen while minimizing the potentially damaging effects of oxidation. Consequently, organisms in all eukaryotic kingdoms display rob
Externí odkaz:
https://doaj.org/article/7246d978081d4c2eaaefcf2803e7a1d6
Autor:
Arnab Pradhan, Qinxi Ma, Emer Hickey, Gabriela Avelar, Daniel Larcombe, Judith Bain, Delma Childers, Ivy Dambuza, Ian Leaves, Leandro Jose de Assis, Mihai Netea, Gordon Brown, Lars Erwig, Neil A. R. Gow, Alistair J. P. Brown
Publikováno v:
Medical Mycology. 60
S9.4 Free oral presentations (late breaking), September 23, 2022, 4:45 PM - 6:15 PM Candida albicans adaptation to host niches affects the exposure of key pathogen-associated molecular patterns (PAMPs) on its cell surface and, consequently, the detec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb315a9d40d762014024316b68299f21
https://doi.org/10.1093/mmy/myac072.s9.4c
https://doi.org/10.1093/mmy/myac072.s9.4c