Zobrazeno 1 - 10
of 291
pro vyhledávání: '"Arn M. J. M. van den Maagdenberg"'
Autor:
Divya Mehta, Irene de Boer, Heidi G. Sutherland, Judith A. Pijpers, Charlene Bron, Charlotte Bainomugisa, Larisa M. Haupt, Arn M. J. M. van den Maagdenberg, Lyn R. Griffiths, Dale R. Nyholt, Gisela M. Terwindt
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-12 (2023)
Abstract Background Chronic migraine, a highly disabling migraine subtype, affects nearly 2% of the general population. Understanding migraine chronification is vital for developing better treatment and prevention strategies. An important factor in t
Externí odkaz:
https://doaj.org/article/733e0f66098746629b8059295d7d35d8
Autor:
Anisa Dehghani, Maarten Schenke, Sandra H. van Heiningen, Hulya Karatas, Else A. Tolner, Arn M. J. M. van den Maagdenberg
Publikováno v:
The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Cortical spreading depolarization (CSD), the neurophysiological correlate of the migraine aura, can activate trigeminal pain pathways, but the neurobiological mechanisms and behavioural consequences remain unclear. Here we investi
Externí odkaz:
https://doaj.org/article/5c9eb621c909401cbf61e50cc3e93767
Autor:
Hande Aydogmus, Michel Hu, Lovro Ivancevic, Jean-Philippe Frimat, Arn M. J. M. van den Maagdenberg, Pasqualina M. Sarro, Massimo Mastrangeli
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Continuous monitoring of tissue microphysiology is a key enabling feature of the organ-on-chip (OoC) approach for in vitro drug screening and disease modeling. Integrated sensing units are particularly convenient for microenvironmental monit
Externí odkaz:
https://doaj.org/article/bab87d7eba4c4f439d2291c7ad74b3b7
Autor:
Adriana Della Pietra, Georgii Krivoshein, Konstantin Ivanov, Raisa Giniatullina, Henna-Kaisa Jyrkkänen, Ville Leinonen, Marko Lehtonen, Arn M. J. M. van den Maagdenberg, Juha Savinainen, Rashid Giniatullin
Publikováno v:
The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Engaging the endocannabinoid system through inhibition of monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH), degrading endocannabinoids (endoCBs) 2-arachidonoylglycerol (2-AG) and anandamide (AEA), was proposed
Externí odkaz:
https://doaj.org/article/d266df3aee0f499db5137d07a714bb31
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/9e0abf2644b44e599782b4317d8bbafe
Autor:
Aster V. E. Harder, Lisanne S. Vijfhuizen, Peter Henneman, Ko Willems van Dijk, Cornelia M. van Duijn, Gisela M. Terwindt, Arn M. J. M. van den Maagdenberg
Publikováno v:
The Journal of Headache and Pain, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Background Migraine is a common brain disorder but reliable diagnostic biomarkers in blood are still lacking. Our aim was to identify, using proton nuclear magnetic resonance (1H-NMR) spectroscopy, metabolites in serum that are associated wi
Externí odkaz:
https://doaj.org/article/c17f732caf81412bac23e40ce1b63a1c
Publikováno v:
The Journal of Headache and Pain, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Neuroinflammation has an important role in the pathophysiology of migraine, which is a complex neuro-glio-vascular disorder. The main aim of this review is to highlight findings of cortical spreading depolarization (CSD)-induced n
Externí odkaz:
https://doaj.org/article/00e39e800d6f42b1bdcc8ad8a448ea76
Autor:
Maxime M. Bos, Neil J. Goulding, Matthew A. Lee, Amy Hofman, Mariska Bot, René Pool, Lisanne S. Vijfhuizen, Xiang Zhang, Chihua Li, Rima Mustafa, Matt J. Neville, Ruifang Li-Gao, Stella Trompet, Marian Beekman, Nienke R. Biermasz, Dorret I. Boomsma, Irene de Boer, Constantinos Christodoulides, Abbas Dehghan, Ko Willems van Dijk, Ian Ford, Mohsen Ghanbari, Bastiaan T. Heijmans, M. Arfan Ikram, J. Wouter Jukema, Dennis O. Mook-Kanamori, Fredrik Karpe, Annemarie I. Luik, L. H. Lumey, Arn M. J. M. van den Maagdenberg, Simon P. Mooijaart, Renée de Mutsert, Brenda W. J. H. Penninx, Patrick C. N. Rensen, Rebecca C. Richmond, Frits R. Rosendaal, Naveed Sattar, Robert A. Schoevers, P. Eline Slagboom, Gisela M. Terwindt, Carisha S. Thesing, Kaitlin H. Wade, Carolien A. Wijsman, Gonneke Willemsen, Aeilko H. Zwinderman, Diana van Heemst, Raymond Noordam, Deborah A. Lawlor
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-20 (2021)
Abstract Background Sleep traits are associated with cardiometabolic disease risk, with evidence from Mendelian randomization (MR) suggesting that insomnia symptoms and shorter sleep duration increase coronary artery disease risk. We combined adjuste
Externí odkaz:
https://doaj.org/article/3a4e89b02a4e4bc9b561d382d0215d2b
Autor:
Michel H. Y. Hu, Jean-Philippe Frimat, Kim Rijkers, Olaf E. M. G. Schijns, Arn M. J. M. van den Maagdenberg, Jim T. A. Dings, Regina Luttge, Govert Hoogland
Publikováno v:
Applied Sciences, Vol 13, Iss 3, p 1432 (2023)
A growing societal awareness is calling upon scientists to reconsider the use of animals in research, which stimulates the development of translational in vitro models. The physiological and architectural interactions between different cell types wit
Externí odkaz:
https://doaj.org/article/326a75b1c75f40a1b234e2fd548a4c1e
Publikováno v:
The Journal of Headache and Pain, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Migraine is a common brain disorder with a large genetic component. Of the two main migraine types, migraine with aura and migraine without aura, the genetic underpinning in the former is least understood. Given the evidence from epidemiolog
Externí odkaz:
https://doaj.org/article/0ef64584009c4369a37289e6c1b66adf