Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Arnóbio Antônio da Silva-Junior"'
Autor:
Anne Emmanuelle Câmara da Silva Melo, Felipe Sanderson Ribeiro de Sousa, Alaine M. dos Santos-Silva, Ednaldo Gomes do Nascimento, Matheus F. Fernandes-Pedrosa, Caroline Addison Carvalho Xavier de Medeiros, Arnóbio Antônio da Silva-Junior
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2649 (2023)
Papain (an enzyme from the latex of Carica papaya) is an interesting natural bioactive macromolecule used as therapeutic alternative for wound healing due to debridement action in devitalized or necrotic tissues. However, its use in high doses can in
Externí odkaz:
https://doaj.org/article/2ebf6c28764648748d7e7c22525c754d
Autor:
Kaliany Adja Medeiros de Araújo, Manoela Torres-Rêgo, Thaynara Gurgel-Medeiros, Arnóbio Antônio da Silva-Júnior, Renner de Souza Leite, Alessandra Daniele-Silva, Matheus de Freitas Fernandes-Pedrosa
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24190- (2024)
Scorpion sting accidents are a public health problem in the state of Rio Grande do Norte, Brazil. The increasing and high incidence of cases in urban areas reveals the importance of studies to determine the epidemiological profile and the spatial dis
Externí odkaz:
https://doaj.org/article/31aa3c0e2975494e85d90800eaba14e3
Autor:
Allanny Alves Furtado, Alessandra Daniele-Silva, Igor Rafael Resende de Oliveira, Raudiney Frankilin Vasconcelos Mendes, Elizabeth Cristina Gomes dos Santos, Enéas de Carvalho, Igor Zumba Damasceno, Adriana Marina e Silva Parente, Kêsia Xisto da Fonseca Ribeiro de Sena, Arnóbio Antônio da Silva-Júnior, Rafael Matos Ximenes, Davi Serradella Vieira, Matheus de Freitas Fernandes-Pedrosa
Publikováno v:
Pharmacological Research, Vol 181, Iss , Pp 106245- (2022)
Multidrug-resistant bacterial infections are a threat to public health worldwide, which boosts the urgent need for pharmacological research for new drugs. Although the peptides without disulfide bridges from scorpions have shown antimicrobial action,
Externí odkaz:
https://doaj.org/article/a2d79f8ef5404570b452c0395ca4823e
Autor:
Renata Carvalho Feitosa, Juliana Souza Ribeiro Costa, Marcelo van Vliet Lima, Elina Sawa Akioka Ishikawa, Karina Cogo Müller, Fernando Bonin Okasaki, Edvaldo Sabadini, Claudia Garnero, Marcela Raquel Longhi, Vladimir Lavayen, Arnóbio Antônio da Silva-Júnior, Laura Oliveira-Nascimento
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1285 (2023)
Doxycycline (DX) is a well-established and broad-spectrum antimicrobial drug. However, DX has drawbacks, such as physicochemical instability in aqueous media and bacterial resistance. The inclusion of drugs in cyclodextrin complexes and their loading
Externí odkaz:
https://doaj.org/article/550c321eb5ff43a0adb00c247b3beb0c
Autor:
Aline de Sousa Barbosa Freitas Pereira, Maria Laura de Souza Lima, Arnobio Antonio da Silva-Junior, Emanuell dos Santos Silva, Raimundo Fernandes de Araújo Júnior, Agnes Andrade Martins, Jovelina Samara Ferreira Alves, Artur de Santana Oliveira, Leandro De Santis Ferreira, Emily Cintia Tossi de Araújo Costa, Gerlane Coelho Bernardo Guerra, Caroline Addison Carvalho Xavier de Medeiros, Gerly A. C. Brito, Renata Ferreira de Carvalho Leitao, Aurigena Antunes de Araújo
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 1576-1584 (2021)
Context Metformin is an important oral anti-hyperglycemic used in diabetes. Polylactic-co-glycolic acid (PLGA) has been widely used due to its reliability in controlling the release of drugs. Objective This study evaluates the in vitro-in vivo availa
Externí odkaz:
https://doaj.org/article/7d4d72e176694e5aa3a792b23b8a3c96
Autor:
Menilla Maria Alves de Melo, Verônica da Silva Oliveira, Moacir Fernandes de Queiroz Neto, Weslley de Souza Paiva, Manoela Torres-Rêgo, Sérgio Ruschi Bergamachi Silva, Daniel de Lima Pontes, Hugo Alexandre Oliveira Rocha, Miguel Ângelo Fonseca de Souza, Arnóbio Antônio da Silva-Júnior, Matheus de Freitas Fernandes-Pedrosa
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2022)
Anionic peptides of scorpions are molecules rich in aspartic and/or glutamic acid residues and correspond to a class of peptides without disulfide bonds that are still little explored. TanP is a linear anionic peptide (50 amino acid residues and net
Externí odkaz:
https://doaj.org/article/f5cf271c642741b488f7f8f40f97ecba
Autor:
Emanuell dos Santos-Silva, Manoela Torres-Rêgo, Fiamma Gláucia-Silva, Renata Carvalho Feitosa, Ariane Ferreira Lacerda, Hugo Alexandre de Oliveira Rocha, Matheus de Freitas Fernandes-Pedrosa, Arnóbio Antônio da Silva-Júnior
Publikováno v:
Toxins, Vol 14, Iss 12, p 888 (2022)
Snakebite envenoming represents a worldwide public health issue. Suitable technologies have been investigated for encapsulated recombinant or native proteins capable of inducing an effective and long-lasting adaptive immune response. Nanoparticles ar
Externí odkaz:
https://doaj.org/article/4c3a01763543429ba3a9b097fe44757b
Autor:
Susana Barbosa Ribeiro, Aurigena Antunes de Araújo, Maisie Mitchele Barbosa Oliveira, Alaine Maria dos Santos Silva, Arnóbio Antônio da Silva-Júnior, Gerlane Coelho Bernardo Guerra, Gerly Anne de Castro Brito, Renata Ferreira de Carvalho Leitão, Raimundo Fernandes de Araújo Júnior, Vinícius Barreto Garcia, Roseane Carvalho Vasconcelos, Caroline Addison Carvalho Xavier de Medeiros
Publikováno v:
Pharmaceutics, Vol 13, Iss 1, p 53 (2021)
Oral mucositis (OM) is characterized by the presence of severe ulcers in the oral region that affects patients treated with chemotherapy. It occurs in almost all patients who receive radiotherapy of the head and neck, as well as patients who undergo
Externí odkaz:
https://doaj.org/article/b122ab58a82d4f3e917b247b22544c1e
Autor:
Tábata L. C. Lima, Luanda B. F. C. Souza, Lannya C. S. Tavares-Pessoa, Alaine M. dos Santos-Silva, Rômulo S. Cavalcante, Raimundo F. de Araújo-Júnior, Alianda M. Cornélio, Matheus F. Fernandes-Pedrosa, Guilherme Maranhão Chaves, Arnóbio Antônio da Silva-Júnior
Publikováno v:
Pharmaceutics, Vol 12, Iss 9, p 871 (2020)
Phytol is a diterpene alcohol and can be found as a product of the metabolism of chlorophyll in plants. This compound has been explored as a potential antimicrobial agent, but it is insoluble in water. In this study, we describe a novel approach for
Externí odkaz:
https://doaj.org/article/7a7f465cd3d74b5f9fabfe481788b05d
Autor:
Arthur Sérgio Avelino de Medeiros, Manoela Torres-Rêgo, Ariane Ferreira Lacerda, Hugo Alexandre Oliveira Rocha, Eryvaldo Sócrates Tabosa do Egito, Alianda Maira Cornélio, Denise V. Tambourgi, Matheus de Freitas Fernandes-Pedrosa, Arnóbio Antônio da Silva-Júnior
Publikováno v:
Pharmaceutics, Vol 12, Iss 10, p 927 (2020)
This study assesses the efficacy of different nanoemulsion formulations as new and innovative adjuvants for improving the in vivo immunization against the Tityus serrulatus scorpion venom. Nanoemulsions were designed testing key-variables such as sur
Externí odkaz:
https://doaj.org/article/8e5558bca6074173b743819fe657a7ec