Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Armstrong, Stephen C"'
Publikováno v:
ETSU Faculty Works.
The hypothesis that irreversible ischemic injury is related to sub-sarcolemmal blebbing and an inherent osmotic fragility of the blebs was tested by subjecting isolated control and ischemically preconditioned (IPC) or calyculin A (CalA)-pretreated (p
Externí odkaz:
https://dc.etsu.edu/etsu-works/19154
Publikováno v:
ETSU Faculty Works.
Sarcolemmal blebbing and rupture are prominent features of irreversible ischemic myocardial injury. Dystrophin and spectrin are sarcolemmal structural proteins. Dystrophin finks the transmembrane dystroglycan complex and extracellular laminin recepto
Externí odkaz:
https://dc.etsu.edu/etsu-works/19159
Autor:
Armstrong, Stephen C.
Publikováno v:
ETSU Faculty Works.
Myocardial ischemia and ischemia/reperfusion activate several protein kinase pathways. Protein kinase activation potentially regulates the onset of myocardial cell injury and the reduction of this injury by ischemic and pharmacologic preconditioning.
Externí odkaz:
https://dc.etsu.edu/etsu-works/18799
Publikováno v:
ETSU Faculty Works.
Alpha B Crystallin (αBC) is a putative effector protein of ischemic preconditioning (IPC). that is phosphorylated on Ser 45 by ERK1/2 and Set 59 by the p38 MAPK substrate, MAPKAPK-2. Translocation and phosphorylation of αBC was determined in cytoso
Externí odkaz:
https://dc.etsu.edu/etsu-works/14585
Publikováno v:
ETSU Faculty Works.
A loss of sarcolemmal dystrophin was observed by immuno-fluorescence studies in rabbit hearts subjected to in situ myocardial ischemia and by immuno-blotting of the Triton soluble membrane fraction of isolated rabbit cardiomyocytes subjected to in vi
Externí odkaz:
https://dc.etsu.edu/etsu-works/13991
Autor:
Diaz, Roberto J., Armstrong, Stephen C., Batthish, Michelle, Backx, Peter H., Ganote, Charles E., Wilson, Gregory J.
Publikováno v:
ETSU Faculty Works.
Accumulation of osmotically active metabolites, which create an osmotic gradient estimated at ∼60 mOsM, and cell swelling are prominent features of ischemic myocardial cell death. This study tests the hypothesis that reduction of ischemic swelling
Externí odkaz:
https://dc.etsu.edu/etsu-works/13947
Publikováno v:
ETSU Faculty Works.
Cell swelling may contribute to acute cell injury subsequent to ischemia/reperfusion. The potential role of mitochondrial uncoupling and the resultant mitochondrial swelling, due to opening of the mitochondrial permeability transition pore (MPTP), we
Externí odkaz:
https://dc.etsu.edu/etsu-works/13946