Výsledky vyhledávání - "Armour John AL"

Akademický článek

Accuracy and differential bias in copy number measurement of CCL3L1 in association studies with three auto-immune disorders

Autor: Carpenter Danielle, Walker Susan, Prescott Natalie, Schalkwijk Joost, Armour John AL

Publikováno v: BMC Genomics, Vol 12, Iss 1, p 418 (2011)

Abstract Background Copy number variation (CNV) contributes to the variation observed between individuals and can influence human disease progression, but the accurate measurement of individual copy numbers is technically challenging. In the work pre

Externí odkaz: https://doaj.org/article/0f38e67e8c7c4fffa170cab32ecdefb4

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Akademický článek

Quadruplex MAPH: improvement of throughput in high-resolution copy number screening

Autor: Walker Susan, Majerus Tamsin MO, Tyson Jess, Armour John AL

Publikováno v: BMC Genomics, Vol 10, Iss 1, p 453 (2009)

Abstract Background Copy number variation (CNV) in the human genome is recognised as a widespread and important source of human genetic variation. Now the challenge is to screen for these CNVs at high resolution in a reliable, accurate and cost-effec

Externí odkaz: https://doaj.org/article/01a912dcbffa471e87dee4b3f1e13150

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Akademický článek

Directional and balancing selection in human beta-defensins

Autor: Armour John AL, Hollox Edward J

Publikováno v: BMC Evolutionary Biology, Vol 8, Iss 1, p 113 (2008)

Abstract Background In primates, infection is an important force driving gene evolution, and this is reflected in the importance of infectious disease in human morbidity today. The beta-defensins are key components of the innate immune system, with a

Externí odkaz: https://doaj.org/article/8787fb78a6d84c9e88f93619649b9296

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Akademický článek

A 4q35.2 subtelomeric deletion identified in a screen of patients with co-morbid psychiatric illness and mental retardation

Autor: Blackwood Douglas HR, Porteous David J, Malloy M Pat, Hollox Edward J, Pickard Ben S, Armour John AL, Muir Walter J

Publikováno v: BMC Medical Genetics, Vol 5, Iss 1, p 21 (2004)

Abstract Background Cryptic structural abnormalities within the subtelomeric regions of chromosomes have been the focus of much recent research because of their discovery in a percentage of people with mental retardation (UK terminology: learning dis

Externí odkaz: https://doaj.org/article/39d73e89739c4fba90c228d43f78a645

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