Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Armina Madatian"'
Autor:
William M. Hardesty, Fangming Xia, Armina Madatian, Ernest M. Schubert, Peter D. Gorycki, Yanli Deng, Jennifer L. Seymour, Catherine D. Tsalta
Publikováno v:
Drug Metabolism and Disposition. 39:1620-1632
GSK977779 is a potent HM74a agonist evaluated for the treatment of dyslipidemia. The disposition and metabolism of [(14)C]GSK977779 (67.6 μmol/kg p.o.) was studied in male and female rats. The compound was well absorbed and its primary route of elim
Autor:
Frances Gorycki, Mark A. Levy, Ernest M. Schubert, Jung Wook Park, Peter D. Gorycki, Mary Beth Wire, Yanli Deng, Daphne Williams, Armina Madatian, Carolyn J. Bowen, Bin Peng
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 39(9)
The metabolism and disposition of eltrombopag, the first-in-class small molecule human thrombopoietin receptor agonist, were studied in six healthy men after a single oral administration of a solution dose of [(14)C]eltrombopag (75 mg, 100 μCi). Elt