Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Armin W. Opitz"'
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1828(2):294-301
Targeted delivery of imaging agents to cells can be optimized with the understanding of uptake and efflux rates. Cellular uptake of macromolecules is studied frequently with fluorescent probes. We hypothesized that the internalization and efflux of f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2763c31a72fc0ebecaee08ae2d8898d4
Publikováno v:
Oligonucleotides. 20:117-125
Disease detection and management might benefit from external imaging of disease gene mRNAs. Previously we designed molecular imaging nanoparticles (MINs) based on peptide nucleic acids complementary to cancer gene mRNAs. The MINs included contrast ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b867ec61f649f5da5047fa214e446919
https://doi.org/10.1089/oli.2009.0216
https://doi.org/10.1089/oli.2009.0216
Autor:
Eric Wickstrom, Christopher Cardi, Mohan R. Aruva, Mathew L. Thakur, Armin W. Opitz, Kaijun Zhang, A. Chakrabarti, Norman J. Wagner
Publikováno v:
Cancer Biology & Therapy. 6:948-956
There is a compelling need to image pancreas cancer at an early stage. Human pancreas cancer cells display elevated levels of KRAS protein due to high copy numbers of KRAS mRNA, and elevated levels of insulin-like growth factor 1 receptor (IGF1R) due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803cc458754493505f8eef3c1da36822
https://doi.org/10.4161/cbt.6.6.4191
https://doi.org/10.4161/cbt.6.6.4191
Autor:
Armin W. Opitz, Norman J. Wagner
Publikováno v:
Journal of Polymer Science Part B: Polymer Physics. 44:3062-3077
The molecular structure of poly(amido amine) dendrimers is investigated with molecular dynamics simulations using the Amber 7 modeling package. A method for defining residues for complex molecules is developed, and it enables the study of the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e97f94ca07ca02ac880e7894532dcf43
https://doi.org/10.1002/polb.20949
https://doi.org/10.1002/polb.20949
Autor:
Norman J. Wagner, Christopher Cardi, Armin W. Opitz, Song Lai, Nariman V. Amirkhanov, Ivan E. Dimitrov, John Lackey, Kaijun Zhang, Mathew L. Thakur, Eric Wickstrom
Publikováno v:
Biopolymers. 89(12)
We hypothesized that chelating Gd(III) to 1,4,7-tris(carboxymethylaza)cyclododecane-10-azaacetylamide (DO3A) on peptide nucleic acid (PNA) hybridization probes would provide a magnetic resonance genetic imaging agent capable of hybridization to a spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33343710e30f3e2450de1d1bdd009a7
https://pubmed.ncbi.nlm.nih.gov/18680101
https://pubmed.ncbi.nlm.nih.gov/18680101