SARS-CoV-2 evolution balances conflicting roles of N protein phosphorylation.

Autor: Abdullah M Syed, Alison Ciling, Irene P Chen, Christopher R Carlson, Armin N Adly, Hannah S Martin, Taha Y Taha, Mir M Khalid, Nathan Price, Mehdi Bouhaddou, Manisha R Ummadi, Jack M Moen, Nevan J Krogan, David O Morgan, Melanie Ott, Jennifer A Doudna

Publikováno v: PLoS Pathogens, Vol 20, Iss 11, p e1012741 (2024)

All lineages of SARS-CoV-2, the coronavirus responsible for the COVID-19 pandemic, contain mutations between amino acids 199 and 205 in the nucleocapsid (N) protein that are associated with increased infectivity. The effects of these mutations have b

Externí odkaz: https://doaj.org/article/dc538930b2c84bdf884ebe6d02b5f631

SARS-CoV-2 evolution balances conflicting roles of N protein phosphorylation.

Autor: Syed, Abdullah M.¹ (AUTHOR), Ciling, Alison¹ (AUTHOR), Chen, Irene P.^1,2 (AUTHOR), Carlson, Christopher R.³ (AUTHOR), Adly, Armin N.³ (AUTHOR), Martin, Hannah S.⁴ (AUTHOR), Taha, Taha Y.¹ (AUTHOR), Khalid, Mir M.¹ (AUTHOR), Price, Nathan¹ (AUTHOR), Bouhaddou, Mehdi^1,5,6,7,8,9 (AUTHOR), Ummadi, Manisha R.^1,7,8,9 (AUTHOR), Moen, Jack M.^1,7,8,9 (AUTHOR), Krogan, Nevan J.^1,7,8,9,10 (AUTHOR), Morgan, David O.³ (AUTHOR), Ott, Melanie^1,2 (AUTHOR), Doudna, Jennifer A.^{1,11,12,13,14,15} (AUTHOR) doudna@berkeley.edu

Publikováno v: PLoS Pathogens. 11/21/2024, Vol. 20 Issue 11, p1-22. 22p.