Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Armin Deffur"'
Autor:
Ursula K. Rohlwink, Anthony Figaji, Katalin A. Wilkinson, Stuart Horswell, Abdul K. Sesay, Armin Deffur, Nico Enslin, Regan Solomons, Ronald Van Toorn, Brian Eley, Michael Levin, Robert J. Wilkinson, Rachel P. J. Lai
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Tuberculosis meningitis (TBM) is a severe form of TB with limited treatment options. Here, the authors perform RNA sequencing on whole blood and on ventricular and lumbar cerebrospinal fluid (CSF) samples from pediatric patients treated for TBM to ch
Externí odkaz:
https://doaj.org/article/11b7cc57037a47a2b99a6a49c4d9e072
Publikováno v:
Wellcome Open Research, Vol 3 (2018)
Contextual functional interpretation of -omics data derived from clinical samples is a classical and difficult problem in computational systems biology. The measurement of thousands of data points on single samples has become routine but relating ‘
Externí odkaz:
https://doaj.org/article/2ee0dc18bee64945a86442c4a4e99754
Publikováno v:
Wellcome Open Research, Vol 3 (2018)
Contextual functional interpretation of -omics data derived from clinical samples is a classical and difficult problem in computational systems biology. The measurement of thousands of data points on single samples has become routine but relating ‘
Externí odkaz:
https://doaj.org/article/b251e4530b8041369ef688b76c910202
Autor:
Justin Shenje, F. Ifeoma Adimora-Nweke, Ian L. Ross, Mpiko Ntsekhe, Lubbe Wiesner, Armin Deffur, Helen M. McIlleron, Jotam Pasipanodya, Tawanda Gumbo, Bongani M. Mayosi
Publikováno v:
EBioMedicine, Vol 2, Iss 11, Pp 1640-1649 (2015)
Pericardial tuberculosis (TB) is associated with high therapy failure and high mortality rates. Antibiotics have to penetrate to site of infection at sufficient non-protein bound concentrations, and then enter bacteria to inhibit intracellular bioche
Externí odkaz:
https://doaj.org/article/400eed28884e41d28422c8c999751b16
Autor:
Mpiko Ntsekhe, Kerryn Matthews, Faisal F Syed, Armin Deffur, Motasim Badri, Patrick J Commerford, Bernard J Gersh, Katalin A Wilkinson, Robert J Wilkinson, Bongani M Mayosi
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77532 (2013)
BACKGROUND:Effusive constrictive pericarditis (ECP) is visceral constriction in conjunction with compressive pericardial effusion. The prevalence of proven tuberculous ECP is unknown. Whilst ECP is distinguished from effusive disease on hemodynamic g
Externí odkaz:
https://doaj.org/article/0b2229db51874c9e9b129e62265ee4da
Aging is an inevitable process of cellular and physiological decline. These markers of age can be measured on the molecular and functional level. Wearable devices offer a non-invasive continuous measure of physiological and behavioural features and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab5ceee22e26d124ab17444039602f35
https://doi.org/10.1101/2023.04.11.536462
https://doi.org/10.1101/2023.04.11.536462
Autor:
Armin Deffur, Abdul Karim Sesay, Regan Solomons, Nico Enslin, Ursula K. Rohlwink, Robert J. Wilkinson, Michael Levin, Ronald van Toorn, Katalin A. Wilkinson, Stuart Horswell, Rachel P. J. Lai, Anthony Figaji, Brian Eley
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Nature Communications
Nature Communications
Tuberculous meningitis (TBM) is the most severe form of TB with high rates of mortality and morbidity. Here we conduct RNA-sequencing on whole blood as well as on ventricular and lumbar cerebrospinal fluid (CSF) of pediatric patients treated for TBM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd69fab005b5a38b677215784262cd45
https://doaj.org/article/11b7cc57037a47a2b99a6a49c4d9e072
https://doaj.org/article/11b7cc57037a47a2b99a6a49c4d9e072
Autor:
Ian L. Ross, Armin Deffur, Tawanda Gumbo, Jotam G. Pasipanodya, Justin Shenje, Mpiko Ntsekhe, F. Ifeoma Adimora-Nweke, Bongani M. Mayosi, Lubbe Wiesner, Helen McIlleron
Publikováno v:
EBioMedicine, Vol 2, Iss 11, Pp 1640-1649 (2015)
EBioMedicine
EBioMedicine
Pericardial tuberculosis (TB) is associated with high therapy failure and high mortality rates. Antibiotics have to penetrate to site of infection at sufficient non-protein bound concentrations, and then enter bacteria to inhibit intracellular bioche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca76790c49264da8e2454ede8c87589e
Autor:
Naomi F. Walker, Molebogeng X. Rangaka, Robert J. Wilkinson, Gurdyal S. Besra, Rebecca Tadokera, Keira H. Skolimowska, Katalin A. Wilkinson, Mark P. Nicol, Armin Deffur, Kerryn Matthews, Gary Maartens, Graeme Meintjes, Ronnett Seldon
Publikováno v:
The Journal of Immunology Author Choice
Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) frequently complicates combined antiretroviral therapy and antituberculosis therapy in HIV-1–coinfected tuberculosis patients. The immunopathological mechanisms underlyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d2aa8c70a12bb94131612e0c198539
http://europepmc.org/articles/PMC4319311
http://europepmc.org/articles/PMC4319311
Autor:
Katalin A. Wilkinson, Mpiko Ntsekhe, James R Russell, Armin Deffur, Bongani M. Mayosi, Robert J. Wilkinson, Kerryn Matthews, Thomas J. Scriba, Faisal F. Syed, Willem A. Hanekom, Kemi Tibazarwa
Publikováno v:
European Journal of Immunology. 42:147-157
HIV-1-infected people have an increased risk of developing extrapulmonary tuberculosis (TB), the immunopathogenesis of which is poorly understood. Here, we conducted a detailed immunological analysis of human pericardial TB, to determine the effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e0e5b50291528529bdbe38dcb2e5e55
https://doi.org/10.1002/eji.201141927
https://doi.org/10.1002/eji.201141927