Zobrazeno 1 - 10
of 238
pro vyhledávání: '"Armin Buschauer"'
Publikováno v:
ACS Omega, Vol 3, Iss 3, Pp 2865-2882 (2018)
Externí odkaz:
https://doaj.org/article/383a0c58703247f6979a55e7f6c21bea
Autor:
Kilian K. Kuhn, Timo Littmann, Stefanie Dukorn, Miho Tanaka, Max Keller, Takeaki Ozawa, Günther Bernhardt, Armin Buschauer
Publikováno v:
ACS Omega, Vol 2, Iss 7, Pp 3616-3631 (2017)
Externí odkaz:
https://doaj.org/article/56c031c8429644c8b1dea5927f73ff04
Autor:
Zoya Orlando, Isabelle Lengers, Matthias F. Melzig, Armin Buschauer, Andreas Hensel, Joachim Jose
Publikováno v:
Molecules, Vol 20, Iss 9, Pp 15449-15468 (2015)
Hyaluronan (HA) is the main component of the extracellular matrix (ECM). Depending on its chain size, it is generally accepted to exert diverse effects. High molecular weight HA is anti-angiogenic, immunosuppressive and anti-inflammatory, while lower
Externí odkaz:
https://doaj.org/article/552c1452460e43598da0f2b5948e0162
Publikováno v:
Molecules, Vol 18, Iss 11, Pp 14186-14202 (2013)
Premedication with a combination of histamine H1 receptor (H1R) and H2 receptor (H2R) antagonists has been suggested as a prophylactic principle, for instance, in anaesthesia and surgery. Aiming at pharmacological hybrids combining H1R and H2R antago
Externí odkaz:
https://doaj.org/article/da987d7bdb7b42d7bc19cede975e62ec
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0117185 (2015)
In contrast to the corresponding mouse and rat orthologs, the human histamine H4 receptor (hH4R) shows extraordinarily high constitutive activity. In the extracellular loop (ECL), replacement of F169 by V as in the mouse H4R significantly reduced con
Externí odkaz:
https://doaj.org/article/610624632ce14fd8b40726e09588250a
Autor:
Stefan Huber, Johannes Philip Huettner, Kristina Hacker, Günther Bernhardt, Jörg König, Armin Buschauer
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133743 (2015)
The alkylating agent bendamustine is approved for the treatment of hematopoietic malignancies such as non-Hodgkin lymphoma, chronic lymphocytic leukemia and multiple myeloma. As preliminary data on recently disclosed bendamustine esters suggested inc
Externí odkaz:
https://doaj.org/article/1460d18d2f3d4436988c621665e14fec
Autor:
Uwe Nordemann, David Wifling, David Schnell, Günther Bernhardt, Holger Stark, Roland Seifert, Armin Buschauer
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73961 (2013)
The investigation of the (patho)physiological role of the histamine H4 receptor (H4R) and its validation as a possible drug target in translational animal models are compromised by distinct species-dependent discrepancies regarding potencies and rece
Externí odkaz:
https://doaj.org/article/fc716c87b4f8424da737494f98cce70f
Autor:
Irena Brunskole Hummel, Michael T Reinartz, Solveig Kälble, Heike Burhenne, Frank Schwede, Armin Buschauer, Roland Seifert
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64556 (2013)
In neutrophils, activation of the β2-adrenergic receptor (β2AR), a Gs-coupled receptor, inhibits inflammatory responses, which could be therapeutically exploited. The aim of this study was to evaluate the effects of various β2AR ligands on adenosi
Externí odkaz:
https://doaj.org/article/bea713f0dd944c708b2197156e85c245
Autor:
Martin Memminger, Max Keller, Miroslaw Lopuch, Nathalie Pop, Günther Bernhardt, Erwin von Angerer, Armin Buschauer
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51032 (2012)
The neuropeptide Y (NPY) Y(1) receptor (Y(1)R) has been suggested as a tumor marker for in vivo imaging and as a therapeutic target. In view of the assumed link between estrogen receptor (ER) and Y(1)R in mammary carcinoma and with respect to the dev
Externí odkaz:
https://doaj.org/article/abef60db5c2d42e099c52d0f0c76f602
Publikováno v:
ChemistryOpen, Vol 8, Iss 3, Pp 285-297 (2019)
Abstract New classes of alkylated hetarylpropylguanidines with different functionality and variation in spacer length were synthesized to determine their behavior at the four histamine receptor (H1R, H2R, H3R, H4R) subtypes. Alkylated guanidines with
Externí odkaz:
https://doaj.org/article/b572012a2d9e45b285cef563b4e460bb