Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Armetta Hill"'
Autor:
Charles W. Wright, Naomi Li, Lynsey Shaffer, Armetta Hill, Nicolas Boyer, Stephen E. Alves, Sriraman Venkataraman, Kaustav Biswas, Linda A. Lieberman, Sina Mohammadi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Disruptions in the gut epithelial barrier can lead to the development of chronic indications such as inflammatory bowel disease (IBD). Historically, barrier function has been assessed in cancer cell lines, which do not contain all human inte
Externí odkaz:
https://doaj.org/article/53dd0fbf350741229b237e3cc1522057
Autor:
Charles W. Wright, Naomi Li, Lynsey Shaffer, Armetta Hill, Nicolas Boyer, Stephen Alves, Sriram Venkat, Kaustav Biswas, Linda A. Lieberman, Sina Mohammadi
Disruptions in the gut epithelial barrier can lead to the development of chronic indications such as inflammatory bowel disease (IBD). Historically, barrier function has been assessed in cancer cell lines, which do not contain all human intestinal ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a5c487ef12d61187d57398773a1b32a
https://doi.org/10.1101/2022.12.16.520780
https://doi.org/10.1101/2022.12.16.520780
Autor:
Joey L. Methot, Hua Zhou, Sam D. Kattar, Meredeth A. McGowan, Kevin Wilson, Yudith Garcia, Yongi Deng, Michael Altman, Xavier Fradera, Charles Lesburg, Thierry Fischmann, Chaomin Li, Steve Alves, Sanjiv Shah, Rafael Fernandez, Peter Goldenblatt, Armetta Hill, Lynsey Shaffer, Dapeng Chen, Vince Tong, Robbie L. McLeod, Hongshi Yu, Alan Bass, Ray Kemper, Nicholas T. Gatto, Lisa LaFranco-Scheuch, Benjamin Wesley Trotter, Timothy Guzi, Jason D. Katz
Publikováno v:
Journal of Medicinal Chemistry. 62:4370-4382
PI3Kδ catalytic activity is required for immune cell activation, and has been implicated in inflammatory diseases as well as hematological malignancies in which the AKT pathway is overactive. A purine PI3Kδ inhibitor bearing a benzimidazolone-piper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22455e06a228a36e7b0e36ea97794591
https://doi.org/10.1021/acs.jmedchem.8b01818
https://doi.org/10.1021/acs.jmedchem.8b01818
Autor:
Wright, Charles W.1 (AUTHOR), Li, Naomi2 (AUTHOR), Shaffer, Lynsey2,3 (AUTHOR), Hill, Armetta2 (AUTHOR), Boyer, Nicolas4 (AUTHOR), Alves, Stephen E.1 (AUTHOR), Venkataraman, Sriraman2 (AUTHOR), Biswas, Kaustav4 (AUTHOR), Lieberman, Linda A.1 (AUTHOR), Mohammadi, Sina1 (AUTHOR) sina.mohammadi@merck.com
Publikováno v:
Scientific Reports. 11/20/2023, Vol. 13 Issue 1, p1-12. 12p.
Publikováno v:
Gastroenterology Week; 10/16/2023, p545-545, 1p