Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Armend Axhemi"'
Publikováno v:
RNA. 27:465-476
The 3′ to 5′ exonuclease Pop2p (Caf1p) is part of the CCR4-NOT deadenylation complex that removes poly(A) tails from mRNAs in cells. Pop2p is structurally conserved in eukaryotes, but Saccharomyces cerevisiae Pop2p harbors noncanonical amino acid
Publikováno v:
Nucleic Acids Research
The mechanism for how internal ribosome entry sites (IRESs) recruit ribosomes to initiate translation of an mRNA is not completely understood. We investigated how a 40S subunit was recruited by the cricket paralysis virus intergenic region (CrPV IGR)
Publikováno v:
Proc Natl Acad Sci U S A
The exoribonuclease Rrp6p is critical for RNA decay in the nucleus. While Rrp6p acts on a large range of diverse substrates, it does not indiscriminately degrade all RNAs. How Rrp6p accomplishes this task is not understood. Here, we measure Rrp6p-RNA
RNA turnover pathways ensure appropriate gene expression levels by eliminating unwanted transcripts that may otherwise interfere with cellular programs. The enzyme Dis3-like protein 2 (Dis3L2) is a 3’-5’ exoribonuclease that, through its RNA turn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9406bcf6c465ada0e5a821d74ebf3b3
https://doi.org/10.1101/2021.11.30.470623
https://doi.org/10.1101/2021.11.30.470623
Publikováno v:
RNA (New York, N.Y.). 27(4)
The 3' to 5' exonuclease Pop2p (Caf1p) is part of the CCR4-NOT deadenylation complex that removes poly(A) tails from mRNAs in cells. Pop2p is structurally conserved in eukaryotes, but
Autor:
Magdalena Malgowska, Sukanya Srinivasan, Eckhard Jankowsky, Yinghua Chen, Derek J. Taylor, Armend Axhemi, Mengyuan Xu, Daniel Leonard
Publikováno v:
J Mol Biol
Chromosome ends are protected by guanosine-rich telomere DNA that forms stable G-quadruplex (G4) structures. The heterodimeric POT1-TPP1 complex interacts specifically with telomere DNA to shield it from illicit DNA damage repair and to resolve secon
Autor:
Donald W. Jacobsen, Luciana Hannibal, Keerthana Bolisetty, Patricia M. DiBello, Sergey N. Fedosov, Armend Axhemi, Edward V. Quadros
Publikováno v:
Hannibal, L, Bolisetty, K, Axhemi, A, DiBello, P M, Quadros, E V, Fedosov, S & Jacobsen, D W 2018, ' Transcellular transport of cobalamin in aortic endothelial cells ', FASEB Journal, vol. 32, no. 10, pp. 5506-5519 . https://doi.org/10.1096/fj.201701141RR
Cobalamin [Cbl (or B(12))] deficiency causes megaloblastic anemia and a variety of neuropathies. However, homeostatic mechanisms of cyanocobalamin (CNCbl) and other Cbls by vascular endothelial cells are poorly understood. Herein, we describe our inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02cab1bb4494d3dca1c91073f68892c1
https://pure.au.dk/portal/da/publications/transcellular-transport-of-cobalamin-in-aortic-endothelial-cells(9dca9759-fe9d-4595-ac25-77bb7704b953).html
https://pure.au.dk/portal/da/publications/transcellular-transport-of-cobalamin-in-aortic-endothelial-cells(9dca9759-fe9d-4595-ac25-77bb7704b953).html
Autor:
Hui Tang, Laura E. Nagy, Antoinette D. Hillian, Xiaocong Chen, Becky M. Sebastian, Donald W. Jacobsen, Armend Axhemi
Publikováno v:
Alcoholism: Clinical and Experimental Research. 36:214-222
Background: Adipose tissue is an important target for ethanol action. One important effect of ethanol is to reduce the secretion of adiponectin from adipocytes; this decrease is associated with lowered circulating adiponectin in rodent models of chro
Autor:
Hui Tang, Donald W. Jacobsen, Becky M. Sebastian, Laura E. Nagy, Armend Axhemi, Megan Mr McMullen, Xiaocong Chen
Publikováno v:
Hepatology. 49:1554-1562
Adiponectin, an adipokine primarily secreted by adipose tissue, comprises about 0.01% of total serum protein (1). It circulates in three oligomeric forms: high molecular weight (HMW), middle molecular weight (MMW) and low molecular weight (LMW). Adip
Autor:
Hui, Tang, Becky M, Sebastian, Armend, Axhemi, Xiaocong, Chen, Antoinette D, Hillian, Donald W, Jacobsen, Laura E, Nagy
Publikováno v:
Alcoholism, clinical and experimental research. 36(2)
Adipose tissue is an important target for ethanol action. One important effect of ethanol is to reduce the secretion of adiponectin from adipocytes; this decrease is associated with lowered circulating adiponectin in rodent models of chronic ethanol