Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Armen Y Mulkidjanian"'
Autor:
Alexander A. Malär, Nino Wili, Laura A. Völker, Maria I. Kozlova, Riccardo Cadalbert, Alexander Däpp, Marco E. Weber, Johannes Zehnder, Gunnar Jeschke, Hellmut Eckert, Anja Böckmann, Daniel Klose, Armen Y. Mulkidjanian, Beat H. Meier, Thomas Wiegand
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Here, the authors use solid-state NMR and EPR measurements to characterise the ATP hydrolysis transition state of the oligomeric bacterial DnaB helicase from Helicobacter pylori, which was trapped by using aluminium fluoride as a chemical mimic. They
Externí odkaz:
https://doaj.org/article/eb891282fac642d58cd86a545184715e
Autor:
Vladimir P. Skulachev, Mikhail Yu. Vyssokikh, Boris V. Chernyak, Armen Y. Mulkidjanian, Maxim V. Skulachev, Gregory A. Shilovsky, Konstantin G. Lyamzaev, Vitaliy B. Borisov, Fedor F. Severin, Victor A. Sadovnichii
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12540 (2023)
Cellular respiration is associated with at least six distinct but intertwined biological functions. (1) biosynthesis of ATP from ADP and inorganic phosphate, (2) consumption of respiratory substrates, (3) support of membrane transport, (4) conversion
Externí odkaz:
https://doaj.org/article/e0c1fa324f424ca8a9e70842da931f30
Publikováno v:
Biomolecules, Vol 12, Iss 10, p 1346 (2022)
To clarify the obscure hydrolysis mechanism of ubiquitous P-loop-fold nucleoside triphosphatases (Walker NTPases), we analysed the structures of 3136 catalytic sites with bound Mg-NTP complexes or their analogues. Our results are presented in two art
Externí odkaz:
https://doaj.org/article/fd4eb8263e484062bc9e4f10ac24a55d
Publikováno v:
Biomolecules, Vol 12, Iss 10, p 1345 (2022)
The P-loop fold nucleoside triphosphate (NTP) hydrolases (also known as Walker NTPases) function as ATPases, GTPases, and ATP synthases, are often of medical importance, and represent one of the largest and evolutionarily oldest families of enzymes.
Externí odkaz:
https://doaj.org/article/d8abcd88de984485b7e8078874551d10
Autor:
Philipp S. Orekhov, Marine E. Bozdaganyan, Natalia Voskoboynikova, Armen Y. Mulkidjanian, Maria G. Karlova, Anna Yudenko, Alina Remeeva, Yury L. Ryzhykau, Ivan Gushchin, Valentin I. Gordeliy, Olga S. Sokolova, Heinz-Jürgen Steinhoff, Mikhail P. Kirpichnikov, Konstantin V. Shaitan
Publikováno v:
Nanomaterials, Vol 12, Iss 3, p 361 (2022)
Amphiphilic copolymers consisting of alternating hydrophilic and hydrophobic units account for a major recent methodical breakthrough in the investigations of membrane proteins. Styrene–maleic acid (SMA), diisobutylene–maleic acid (DIBMA), and re
Externí odkaz:
https://doaj.org/article/a167d1deab034ef9be66ba5862c0bb35
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13480 (2021)
In humans, over-activation of innate immunity in response to viral or bacterial infections often causes severe illness and death. Furthermore, similar mechanisms related to innate immunity can cause pathogenesis and death in sepsis, massive trauma (i
Externí odkaz:
https://doaj.org/article/0cedc9cbc8bb4bc4800f5f54d8bac14b
Autor:
Maria Karlova, Natalia Voskoboynikova, Armen Y. Mulkidjanian, Konstantin V. Shaitan, Heinz-Jürgen Steinhoff, Jürgen J. Heinisch, Olga S. Sokolova
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss Suppl_1, Pp 16-16 (2021)
Background: Wsc1 is the best studied of the five mechanosensors of the cell wall integrity (CWI) signal transduction pathway in Saccharomyces cerevisiae. In genetic and biophysical studies, Wsc1 functions were assessed either in living yeast cells or
Externí odkaz:
https://doaj.org/article/574ec6b5a0564d10a0bb8839356139a7
Autor:
Daria V. Dibrova, Kirill A. Konovalov, Vadim V. Perekhvatov, Konstantin V. Skulachev, Armen Y. Mulkidjanian
Publikováno v:
Biology Direct, Vol 12, Iss 1, Pp 1-11 (2017)
Abstract Background The Clusters of Orthologous Groups (COGs) of proteins systematize evolutionary related proteins into specific groups with similar functions. However, the available databases do not provide means to assess the extent of similarity
Externí odkaz:
https://doaj.org/article/171e160e6f454fd794c6b493fde6cdf0
Autor:
Olesya I. Klimchuk, Kirill A. Konovalov, Vadim V. Perekhvatov, Konstantin V. Skulachev, Daria V. Dibrova, Armen Y. Mulkidjanian
Publikováno v:
Biology Direct, Vol 12, Iss 1, Pp 1-7 (2017)
Abstract Background In prokaryotic genomes, functionally coupled genes can be organized in conserved gene clusters enabling their coordinated regulation. Such clusters could contain one or several operons, which are groups of co-transcribed genes. Th
Externí odkaz:
https://doaj.org/article/2572dc15872a4fc1883e8320e4992e60
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Tau is a neuronal microtubule-associated protein (MAP) that is involved in the regulation of axonal microtubule assembly. However, as a protein with intrinsically disordered regions (IDRs), tau also interacts with many other partners in addition to m
Externí odkaz:
https://doaj.org/article/f86da85bd06847a8a49a889724023edb