Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Armen V Gyulkhandanyan"'
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 25 (2019)
In nucleated cells, the extrinsic pathway of the programmed cell death (apoptosis) is triggered by interaction of death ligands of the tumor necrosis factor superfamily with the death receptors on external cell surface membrane. In this review, we pr
Externí odkaz:
https://doaj.org/article/e34d439cad974b56842b0d14368f04f4
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis
Platelets may selectively execute apoptosis (PL-Apo), activation (PL-Act), and both or no responses when exposed to different chemical agents, shear stresses, and stored under blood banking conditions. Appropriate diagnosis of PL-Apo is an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cf533b4c49301005c8082d6bf06ac5
http://europepmc.org/articles/PMC6714749
http://europepmc.org/articles/PMC6714749
Autor:
Valery Leytin, Asuman Mutlu, Sergiy Mykhaylov, David J. Allen, Armen V. Gyulkhandanyan, John Freedman
Publikováno v:
Haematologica, Vol 94, Iss 12 (2009)
Externí odkaz:
https://doaj.org/article/e9d5f5848f88457c905c917949c09ab9
Autor:
John Freedman, Armen V. Gyulkhandanyan, David J. Allen, Valery Leytin, Heyu Ni, Sergiy Mykhaylov, Elena Lyubimov
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis. 23:139-147
Availability of universal marker for the diagnosis of platelet apoptosis is an important but currently unresolved goal of platelet physiology investigations. Mitochondrial inner transmembrane potential (▵Ψm) depolarization is frequently used as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a605312804fa571a37fead8fba6f80
https://doi.org/10.1177/1076029616665924
https://doi.org/10.1177/1076029616665924
Publikováno v:
British journal of haematology. 181(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c9db260d6a9be2543855acb0c4b742
https://pubmed.ncbi.nlm.nih.gov/28832974
https://pubmed.ncbi.nlm.nih.gov/28832974
Publikováno v:
British Journal of Haematology. 163:377-384
Summary The cell plasma membrane is tightly coupled with the vital processes of apoptosis and activation. In the current study, we investigated exposure of the apoptosis marker phosphatidylserine (PS) and activation marker P-selectin (CD62) on the pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3381577a560995ef72713331cb51d0af
https://doi.org/10.1111/bjh.12529
https://doi.org/10.1111/bjh.12529
Publikováno v:
British Journal of Haematology. 161:245-254
Summary Anucleate platelets perform two fundamental processes, activation and apoptosis. We elaborated an approach for selective and concurrent stimulation of platelet apoptosis and/or activation, processes important in haemostasis and platelet clear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ebf3e48da5d00cf4cdc5715f0d0452
https://doi.org/10.1111/bjh.12237
https://doi.org/10.1111/bjh.12237
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis
Clinical and Applied Thrombosis/Hemostasis, Vol 25 (2019)
Clinical and Applied Thrombosis/Hemostasis, Vol 25 (2019)
In nucleated cells, the extrinsic pathway of the programmed cell death (apoptosis) is triggered by interaction of death ligands of the tumor necrosis factor superfamily with the death receptors on external cell surface membrane. In this review, we pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e4db6e99cc09ee8e49f97a91e95067
https://doi.org/10.1177/1076029619853641
https://doi.org/10.1177/1076029619853641
Autor:
Alexandre B. Hardy, Michael B. Wheeler, Herbert Y. Gaisano, Nadeeja Wijesekara, Pejman Raeisi Giglou, Sobia Sultan, Alpana Bhattacharjee, Armen V. Gyulkhandanyan, Patrick E. MacDonald, Jocelyn E. Manning Fox
Publikováno v:
Journal of Biological Chemistry. 284:30441-30452
Voltage-gated eag-related gene (Erg) K(+) channels regulate the electrical activity of many cell types. Data regarding Erg channel expression and function in electrically excitable glucagon and insulin producing cells of the pancreas is limited. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bcc629b97225a9ed163316f49467958
https://doi.org/10.1074/jbc.m109.040659
https://doi.org/10.1074/jbc.m109.040659
Autor:
Valery Leytin, Sergiy Mykhaylov, John Freedman, David J. Allen, Armen V. Gyulkhandanyan, Asuman Mutlu
Publikováno v:
Laboratory Investigation. 89:374-384
The role of the mitochondrial permeability transition pore (MPTP) in apoptosis of nucleated cells is well documented. In contrast, the role of MPTP in apoptosis of anucleated platelets is largely unknown. The aim of this study was to elucidate the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6bf1f56f784efd6b60101367db12b0c
https://doi.org/10.1038/labinvest.2009.13
https://doi.org/10.1038/labinvest.2009.13