Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Armen G. Mezhlumyan"'
Autor:
Armen G. Mezhlumyan, Anna V. Tallerova, Polina Y. Povarnina, Aleksey V. Tarasiuk, Nellya M. Sazonova, Tatiana A. Gudasheva, Sergey B. Seredenin
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 284 (2022)
Neurotrophins are considered as an attractive target for the development of antidepressants with a novel mechanism of action. Previously, the dimeric dipeptide mimetics of individual loops of nerve growth factor, NGF (GK-6, loop 1; GK-2, loop 4) and
Externí odkaz:
https://doaj.org/article/d59c9dd10e184a8bb8ce4f2d39ea3d64
Autor:
Tatiana A. Gudasheva, Anna V. Tallerova, Armen G. Mezhlumyan, Tatyana A. Antipova, Ilya O. Logvinov, Yulia N. Firsova, Polina Y. Povarnina, Sergey B. Seredenin
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 252 (2021)
A mimetic of the BDNF loop 4, bis (N-monosuccinyl-L-seryl-L-lysine) hexamethylenediamide, named GSB-106, was designed and synthesized in our scientific group. The compound activated TrkB, MAPK/ERK, PI3K/AKT, and PLCγ in in vitro experiments. In vivo
Externí odkaz:
https://doaj.org/article/fd6b301f445d496195370eaf3ae8921a
Autor:
I. O. Logvinov, Armen G. Mezhlumyan, Anna V. Tallerova, Polina Povarnina, Tatiana A Gudasheva, T. A. Antipova, Yulia N. Firsova, Sergey B. Seredenin
Publikováno v:
Biomolecules
Biomolecules, Vol 11, Iss 252, p 252 (2021)
Volume 11
Issue 2
Biomolecules, Vol 11, Iss 252, p 252 (2021)
Volume 11
Issue 2
A mimetic of the BDNF loop 4, bis (N-monosuccinyl-L-seryl-L-lysine) hexamethylenediamide, named GSB-106, was designed and synthesized in our scientific group. The compound activated TrkB, MAPK/ERK, PI3K/AKT, and PLCγ in in vitro experiments. In vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69eb52d7a4f0292879db9b4820262a3a
https://pubmed.ncbi.nlm.nih.gov/33578683
https://pubmed.ncbi.nlm.nih.gov/33578683