Výsledky vyhledávání - "Armen Changelian"

First In Vivo Testing of Compounds Targeting Group 3 Medulloblastomas Using an Implantable Microdevice as a New Paradigm for Drug Development

Autor: Margot Ernst, Werner Sieghart, Nathalie Y. R. Agar, Kashi Reddy Methuku, Robert Langer, Oliver Jonas, Michael M. Poe, Armen Changelian, Soma Sengupta, Michael J. Cima, Jessica Pierre Francois, Daniel Pomeranz Krummel, Frank Tranghese, Scott L. Pomeroy, David Calligaris, James M. Cook

Publikováno v: Journal of Biomedical Nanotechnology. 12:1297-1302

Medulloblastoma is the most common childhood malignant brain tumor. The most lethal medulloblastoma subtype exhibits a high expression of the GABAA receptor α5 subunit gene and MYC amplification. New benzodiazepines have been synthesized to function

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8628ba8c771bf0d7d2965f5d9d306605
https://doi.org/10.1166/jbn.2016.2262

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Profiling of adrenocorticotropic hormone and arginine vasopressin in human pituitary gland and tumor thin tissue sections using droplet-based liquid-microjunction surface-sampling-HPLC–ESI-MS–MS

Autor: Armen Changelian, Edward R. Laws, Daniel R. Feldman, Sandro Santagata, David Calligaris, Nathalie Y. R. Agar, Vilmos Kertesz, Gary J. Van Berkel

Publikováno v: Analytical and Bioanalytical Chemistry. 407:5989-5998

Described here are the results from the profiling of the proteins arginine vasopressin (AVP) and adrenocorticotropic hormone (ACTH) from normal human pituitary gland and pituitary adenoma tissue sections, using a fully automated droplet-based liquid-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f035b7358fd9a3dff25311415cc077c4
https://doi.org/10.1007/s00216-015-8803-2

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MALDI mass spectrometry imaging analysis of pituitary adenomas for near-real-time tumor delineation

Autor: Ian F. Dunn, Olutayo Olubiyi, Daniel R. Feldman, Armen Changelian, Edward R. Laws, Sandro Santagata, Nathalie Y. R. Agar, Matthew L. Vestal, David Calligaris, Revaz Machaidze, Isaiah Norton

We present a proof of concept study designed to support the clinical development of mass spectrometry imaging (MSI) for the detection of pituitary tumors during surgery. We analyzed by matrix-assisted laser desorption/ionization (MALDI) MSI six nonpa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5811546bc7624cc11841e47c6e259ec3
https://europepmc.org/articles/PMC4538649/

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