Výsledky vyhledávání - "Armen A. Galoyan"

The protective role of a hypothalamic proline-rich peptide during acute intoxication of rats by carbon dioxide in combination with oxygen starvation

Autor: Armen A. Galoyan, R. M. Simonyan, L. N. Arakelyan, G. M. Simonyan, L. H. Melconyan, M. A. Babayan, M. A. Simonyan

Publikováno v: Neurochemical Journal. 7:56-61

We measured the contents of NADPH oxidases (Nox) in the membranes of erythrocytes, spleen cells, bone marrow cells, nuclei from spleen cells, and blood serum of rats that were subjected to action of carbon dioxide under conditions of oxygen starvatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2573873dd1cd619c42aa6215ad65ef59
https://doi.org/10.1134/s1819712412040113

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The protective and immunomodulatory effects of hypothalamic proline-rich polypeptide galarmin against methicillin-resistant Staphylococcus aureus infection in mice

Autor: A. A. Durgaryan, Karina Galoian, M. A. Sargsyan, S. L. Grigoryan, Armen A. Galoyan, M. B. Matevosyan, T. Ye. Seferyan

Publikováno v: European Journal of Clinical Microbiology & Infectious Diseases. 31:2153-2165

The present research summarizes the protective and immunomodulatory activity of hypothalamic proline-rich polypeptide galarmin against methicillin-resistant Staphylococcus aureus (MRSA). The protective effect of galarmin was shown on MRSA-infected an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe9fe5c5b311e2192cac068637caaa0
https://doi.org/10.1007/s10096-012-1550-9

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A morphological-histochemical study of neurodegenerative and regenerative processes in flexor and extensor collaterals of the sciatic nerve after crushing in the presence of PRP-1

Autor: I. B. Meliksetyan, J. S. Sarkissian, V. A. Chavushyan, A. V. Aznauryan, A. L. Minasyan, Armen A. Galoyan

Publikováno v: Neurochemical Journal. 5:278-284

A comparative morphological and histochemical study of the dynamics of de- and regenerative processes in the damaged sciatic nerve (SN) area was conducted in rats at different time points after crushing in the presence of proline-rich peptide (PRP-1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7885debd87f068e7850cd6eb3e27e403
https://doi.org/10.1134/s181971241104012x

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Neuroprotective action of proline-rich polypeptide-1 in β-amyloid induced neurodegeneration in rats

Autor: Karen Safaryan, Michail Aghajanov, I. B. Meliksetyan, Grizelda Navasardyan, V. A. Chavushyan, Konstantin Yenkoyan, Armen A. Galoyan, John S. Sarkissian

Publikováno v: Brain Research Bulletin. 86:262-271

It is recognized that the main trigger of Alzheimer disease related neurodegeneration is β-amyloid peptide, which subsequently generates different metabolic disorders in neuron and finally leads to neuronal death. Several biologically active product

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d8b9263d8e01b8b7eaca4d315eca51b
https://doi.org/10.1016/j.brainresbull.2011.08.003

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The regulatory influence of galarmin on the level and activity of rat tissue metalloproteins after doxorubicin-induced nephro- and cardiotoxicity

Autor: G. A. Kevorkian, L. H. Tadevosyan, Armen A. Galoyan, M. A. Simonyan, L. N. Arakelyan

Publikováno v: Neurochemical Journal. 5:215-219

Doxorubicin (DR) is a potential antineoplastic drug that is used for therapy of different types of malignant tumors (leukemia, lymphoma, mammary tumor, lung, ovarian, pancreatic tumor etc.). However, the long-term use of DR leads to irreversible card

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::def4cf8c7433e8dea5de7548dbf8939f
https://doi.org/10.1134/s1819712411030123

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Cytostatic effect of novel mTOR inhibitor, PRP-1 (galarmin) in MDA 231 (ER−) breast carcinoma cell line. PRP-1 inhibits mesenchymal tumors

Autor: Armen A. Galoyan, Thomas H. Temple, Karina Galoian

Publikováno v: Tumor Biology. 32:745-751

Activation of the PI3K-Akt-mTOR pathway is implicated both in the establishment of tumors and as well as a target for therapy in many types of solid malignancy, its blockade represents an opportunity to improve outcomes in patients with tumors that a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4157be3bc9205061d307a4b7feffb3fd
https://doi.org/10.1007/s13277-011-0176-3

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Effects of stimulation of the hypothalamic nuclei and treatment with a proline-rich peptide on neurons of the superior vestibular nuclei during exposure to vibration

Autor: V. S. Kamenecki, S. M. Minasyan, V. A. Chavushyan, I. B. Meliksetyan, S. H. Sarkisyan, Armen A. Galoyan, J. S. Sarkissian

Publikováno v: Neurochemical Journal. 4:304-313

Vibration impairs functioning of the nervous, cardiovascular, and motor systems. Postvibration disturbances in vestibular function are determined by adaptive changes in neuromediatory processes. We studied the possibility of the regulation of the CNS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::123e3539577ad5726c7a86da393569e0
https://doi.org/10.1134/s1819712410040094

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An increase in the activity of NADPH-dependent O 2 − -producing and ferrihemoglobin-reducing isoforms of cytochrome b 558 from membranes, mitochondria, and nuclei of cells of rats subjected to electrical stimulation of the supraoptic and paraventricular hypothalamic nuclei

Autor: M. A. Babayan, L. G. Melkonyan, R. M. Simonyan, M. A. Simonyan, Armen A. Galoyan, L. N. Arakelyan, G. M. Simonyan, R. L. Airapetyan

Publikováno v: Neurochemical Journal. 4:133-136

Electrical stimulation of supraoptic nuclei (SON) and paraventricular nuclei (PVN) of the hypothalamus increases the immunoreactivity of the rat hypothalamus. However, molecular mechanisms of this effect associated with changes in the level of isofor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e2661a3916328b842f4ef5ecd145f985
https://doi.org/10.1134/s181971241002008x

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Hypothalamic Proline Rich Polypeptide Regulates Hematopoiesis

Autor: Kristina B. Bezirganyan, Tigran K. Davtyan, Armen A. Galoyan

Publikováno v: Neurochemical Research. 35:917-924

The AGAPEPAEPAQPGVY proline-rich polypeptide (PRP-1) was isolated from neurosecretory granules of the bovine neurohypophysis; it is produced by N. supraopticus and N. paraventricularis. It has been shown that PRP-1 has many potentially beneficial bio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54591b220125c4341c675a843ae1a2c4
https://doi.org/10.1007/s11064-009-0109-3

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Antitumorigenic Effect of Brain Proline Rich Polypeptide-1 in Human Chondrosarcoma

Autor: Sean P. Scully, Karina Galoian, Patrick M. Flynn, George McNamara, Armen A. Galoyan

Publikováno v: Neurochemical Research. 34:2117-2121

Proline rich polypeptide (PRP-1) produced by neurosecretory cells of the hypothalamus is one of the fragments of neurophysin-vasopressin-associated glycoprotein. The primary structure of the neuropeptide PRP-1 isolated from neurosecretory granules of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470e44f409241dfff2e6458a697ef1c7
https://doi.org/10.1007/s11064-009-0009-6

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