Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Armelle Logie"'
Autor:
Emma L. Jenkins, Kenji Tamura, Makoto Kodaira, Justin Lindemann, Michael Zinda, Celina M. D'Cruz, Brendon Ladd, Kelly Jacques, Philippa Dudley, Neil James, Vivien Jacobs, Lyndsey Hanson, Claire Crafter, Armelle Logie, Nin Guan, Barry R. Davies
This file contains the supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88b437d053244183f372efec797de0ef
https://doi.org/10.1158/1535-7163.22506828.v1
https://doi.org/10.1158/1535-7163.22506828.v1
Autor:
Emma L. Jenkins, Kenji Tamura, Makoto Kodaira, Justin Lindemann, Michael Zinda, Celina M. D'Cruz, Brendon Ladd, Kelly Jacques, Philippa Dudley, Neil James, Vivien Jacobs, Lyndsey Hanson, Claire Crafter, Armelle Logie, Nin Guan, Barry R. Davies
Supplementary Figure 1: Expression of signalling proteins in MCF10A-AKT1WT and MCF10A-AKT1E17K cells grown in the presence or absence of doxycycline; Supplementary Figure 2: Colony formation in soft agar using MCF10A cells expressing AKT1E17K, AKT1WT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4a86579c7bb9081f8b8e7bccf696df
https://doi.org/10.1158/1535-7163.22506825.v1
https://doi.org/10.1158/1535-7163.22506825.v1
Autor:
Emma L. Jenkins, Kenji Tamura, Makoto Kodaira, Justin Lindemann, Michael Zinda, Celina M. D'Cruz, Brendon Ladd, Kelly Jacques, Philippa Dudley, Neil James, Vivien Jacobs, Lyndsey Hanson, Claire Crafter, Armelle Logie, Nin Guan, Barry R. Davies
AKT1E17K mutations occur at low frequency in a variety of solid tumors, including those of the breast and urinary bladder. Although this mutation has been shown to transform rodent cells in culture, it was found to be less oncogenic than PIK3CA mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e0e51073541b5d806d8c14123aee9a3
https://doi.org/10.1158/1535-7163.c.6538500.v1
https://doi.org/10.1158/1535-7163.c.6538500.v1
Autor:
Emma L. Jenkins, Kenji Tamura, Makoto Kodaira, Justin Lindemann, Michael Zinda, Celina M. D'Cruz, Brendon Ladd, Kelly Jacques, Philippa Dudley, Neil James, Vivien Jacobs, Lyndsey Hanson, Claire Crafter, Armelle Logie, Nin Guan, Barry R. Davies
This file contains the supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::585a71055e1fc0c6250deb273736af2b
https://doi.org/10.1158/1535-7163.22506828
https://doi.org/10.1158/1535-7163.22506828
Autor:
Stephen R. Wedge, Kaye J. Williams, Ian J. Stratford, Camille Debray, Robert W. Wilkinson, Armelle Logie, Muhammed Babur, Paul D. Smith, Brian A. Telfer, Aoife M. Shannon
Purpose: Novel molecularly targeted agents, given in combination with radiotherapy, have the potential to increase tumor response rates and the survival of patients with lung cancer. AZD6244 is a potent and selective inhibitor of mitogen-activated pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c5edb3f29fed763fccf0e8752afc47
https://doi.org/10.1158/1078-0432.c.6517728
https://doi.org/10.1158/1078-0432.c.6517728
Autor:
Paul D. Smith, Sue Cartlidge, Mark Cockerill, Richard Jenkins, Samantha Steele, Paul Martin, Jennifer S. McKay, Armelle Logie, Barry R. Davies
PDF file - 18K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76c9718c8201381922e4693db8f5d6c
https://doi.org/10.1158/1535-7163.22485294
https://doi.org/10.1158/1535-7163.22485294
Autor:
Paul D. Smith, Sue Cartlidge, Mark Cockerill, Richard Jenkins, Samantha Steele, Paul Martin, Jennifer S. McKay, Armelle Logie, Barry R. Davies
Constitutive activation of the extracellular signal-regulated kinase 1/2 (ERK1/2) mitogen-activated protein kinase (MAPK) signaling pathway in human cancers is often associated with mutational activation of BRAF or RAS. MAPK/ERK kinase 1/2 kinases li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5ea77847db5b8626dbd3bb155d54d7
https://doi.org/10.1158/1535-7163.c.6531879
https://doi.org/10.1158/1535-7163.c.6531879
Autor:
Stephen R. Wedge, Kaye J. Williams, Ian J. Stratford, Camille Debray, Robert W. Wilkinson, Armelle Logie, Muhammed Babur, Paul D. Smith, Brian A. Telfer, Aoife M. Shannon
Supplementary Data from The Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase 1/2 Inhibitor AZD6244 (ARRY-142886) Enhances the Radiation Responsiveness of Lung and Colorectal Tumor Xenografts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8d2e11f8765b1aa699d435d28f02e0
https://doi.org/10.1158/1078-0432.22440393
https://doi.org/10.1158/1078-0432.22440393
Autor:
Paul D. Smith, Sylvie M. Guichard, Robert W. Wilkinson, Yi-Long Wu, Jingchuan Zhang, Yi Gu, Christine M. Chresta, Sarah Fenton, Sarah Runswick, Denis Alferez, Barry R. Davies, Armelle Logie, Sarah V. Holt
PDF file - 78K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b09df48d8cda4b53d0141eccb336a91
https://doi.org/10.1158/0008-5472.22392663.v1
https://doi.org/10.1158/0008-5472.22392663.v1
Autor:
James W.T. Yates, Karen Woods, Robert W. Wilkinson, Sarah V. Holt, Kirsty Payne, Barry R. Davies, Armelle Logie, Sylvie Guichard
Publikováno v:
British Journal of Pharmacology. 174:2652-2661
Background AZD8055 is a potent orally available mTOR kinase inhibitor with in vitro and in vivo antitumour activity against a range of tumour types. Preclinical studies showed that AZD8055 induced a dose-dependent pharmacodynamic effect in xenograft