Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Armelle Bohineust"'
Integration of intermittent calcium signals in T cells revealed by temporally patterned optogenetics
Autor:
Béatrice Corre, Yassine El Janati Elidrissi, Justine Duval, Mailys Quilhot, Gaëtan Lefebvre, Solène Ecomard, Fabrice Lemaître, Zacarias Garcia, Armelle Bohineust, Erica Russo, Philippe Bousso
Publikováno v:
iScience, Vol 26, Iss 2, Pp 106068- (2023)
Summary: T cells become activated following one or multiple contacts with antigen-presenting cells. Calcium influx is a key signaling event elicited during these cellular interactions; however, it is unclear whether T cells recall and integrate calci
Externí odkaz:
https://doaj.org/article/129b59cdef164681884d2a17a20e5701
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
The ability to manipulate and monitor calcium signaling in cells in vivo would provide insights into signaling in an endogenous context. Here the authors develop a two-photon-responsive calcium actuator and reporter combination to monitor the effect
Externí odkaz:
https://doaj.org/article/fb7b30514bec4ff1a467119ddb06597e
Autor:
Lionel Le Bourhis, Mathilde Dusseaux, Armelle Bohineust, Stéphanie Bessoles, Emmanuel Martin, Virginie Premel, Maxime Coré, David Sleurs, Nacer-Eddine Serriari, Emmanuel Treiner, Claire Hivroz, Philippe Sansonetti, Marie-Lise Gougeon, Claire Soudais, Olivier Lantz
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003681 (2013)
Mucosal associated invariant T cells (MAIT) are innate T lymphocytes that detect a large variety of bacteria and yeasts. This recognition depends on the detection of microbial compounds presented by the evolutionarily conserved major-histocompatibili
Externí odkaz:
https://doaj.org/article/7bd53988a4ac4006b76003a1105be09d
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19680 (2011)
T cells are major players of adaptive immune response in mammals. Recognition of an antigenic peptide in association with the major histocompatibility complex at the surface of an antigen presenting cell (APC) is a specific and sensitive process whos
Externí odkaz:
https://doaj.org/article/de40cee34ee64cf6af8b9ea27963b453
Autor:
Nicolas Vallet, Sophie Le Grand, Louise Bondeelle, Bénédicte Hoareau, Aurélien Corneau, Delphine Bouteiller, Simon Tournier, Lucille Derivry, Armelle Bohineust, Marie Tourret, Delphine Gibert, Ethan Mayeur, Raphael Itzykson, Kim Pacchiardi, Brian Ingram, Stéphane Cassonnet, Patricia Lepage, Régis Peffault de Latour, Gérard Socié, Anne Bergeron, David Michonneau
Publikováno v:
Blood. 140:2500-2513
Administration of azithromycin after allogeneic hematopoietic stem cell transplantation for hematologic malignancies has been associated with relapse in a randomized phase 3 controlled clinical trial. Studying 240 samples from patients randomized in
Publikováno v:
Bulletin du cancer. 108(10S)
Treatment of hematological malignancies by autologous T cells expressing a chimeric antigen receptor (CAR) is a breakthrough in the field of cancer immunotherapy. As CAR-T cells are entering advanced phases of clinical development, there is a need to
Autor:
Saba Azarnoush, Sophie Caillat-Zucman, Florence Morin, Jean Hugues Dalle, Olivier Lantz, N. Talvard-Balland, Thomas Yvorra, Mélanie Lambert, G. Ben Youssef, Armelle Bohineust, M. F. Chevalier, M. Tourret
BackgroundMucosal associated invariant T (MAIT) cells are semi-invariant T cells that recognize microbial antigens presented by the highly conserved MR1 molecule. MAIT cells are predominantly localized in the liver and barrier tissues and are potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8306cfa946ea33cdefadb07dd1325b03
https://doi.org/10.1101/2021.04.29.21256184
https://doi.org/10.1101/2021.04.29.21256184
Autor:
Armelle Bohineust, Julien Husson, Lionel Guillou, Stéphanie Dogniaux, Claire Hivroz, Avin Babataheri, Michael Saitakis, Abdul I. Barakat
Publikováno v:
Molecular Biology of the Cell
T-lymphocyte passive deformation when squeezing through narrow capillaries is limited by the excess membrane contained in microvilli and membrane folds. During active processes such as transendothelial migration, larger deformations are made possible
Autor:
Stéphanie Dogniaux, Marie Tourret, Sarah Guégan, Francesc Miro, Claire Hivroz, Armelle Bohineust, Karine Chemin
Publikováno v:
The Journal of Immunology. 189:2159-2168
Cytokine secretion by T lymphocytes plays a central role in mounting adaptive immune responses. However, little is known about how newly synthesized cytokines, once produced, are routed within T cells and about the mechanisms involved in regulating t
Publikováno v:
Karolinska Institutet
Dendritic cells (DCs) are professional antigen-presenting cells (APCs) with the unique property of inducing priming and differentiation of naïve CD4+ and CD8+ T cells into helper and cytotoxic effectors. Their efficiency is due to their unique abili