Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism

Autor: Lindstrom, S, Wang, L, Smith, EN, Gordon, W, Vlieg, AV, de Andrade, M, Brody, JA, Pattee, JW, Haessler, J, Brumpton, B, Chasman, DI, Suchon, P, Chen, MH, Turman, C, Germain, M, Wiggins, KL, MacDonald, J, Braekkan, SK, Armasu, SM, Pankratz, N, Jackson, RD, Nielsen, JB, Giulianini, F, Puurunen, MK, Ibrahim, M, Heckbert, SR, Damrauer, SM, Natarajan, P, Klarin, D, de Vries, PS, Sabater-Lleal, M, Huffman, JE, Bammler, TK, Frazer, KA, McCauley, BM, Taylor, K, Pankow, JS, Reiner, AP, Gabrielsen, ME, Deleuze, JF, O'Donnell, CJ, Kim, J, McKnight, B, Kraft, P, Hansen, JB, Rosendaal, FR, Heit, JA, Psaty, BM, Tang, WH, Kooperberg, C, Hveem, K, Ridker, PM, Morange, PE, Johnson, AD, Kabrhel, C, Tregouet, DA, Smith, NL, Busenkell, E, Judy, R, Lynch, J, Levin, M, Aragam, JHK, Chaffin, M, Haas, M, Assimes, TL, Huang, J, Lee, KM, Shao, Q, Huang, YF, Sun, YV, Vujkovic, M, Saleheen, D, Miller, DR, Reaven, P, DuVall, S, Boden, W, Pyarajan, S, Henke, P, Gaziano, JM, Concato, J, Rader, DJ, Cho, K, Chang, KM, Wilson, PWF, Tsao, PS, Kathiresan, S, Obi, A, Million Veteran Program, CHARGE Hemostasis Working Grp, INVENT Consortium

Publikováno v: BLOOD
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

Venous thromboembolism (VTE) is a significant contributor to morbidity and mortality. To advance our understanding of the biology contributing to VTE, we conducted a genome-wide association study (GWAS) of VTE and a transcriptome-wide association stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::723bb5dc0824ccfc1b9d658b0e3cc42c
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2271

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

Autor: Pharoah, PDP, Tsai, YY, Ramus, SJ, Phelan, CM, Goode, EL, Lawrenson, K, Buckley, M, Fridley, BL, Tyrer, JP, Shen, H, Weber, R, Karevan, R, Larson, MC, Song, H, Tessier, DC, Bacot, F, Vincent, D, Cunningham, JM, Dennis, J, Dicks, E, Aben, KK, Anton-Culver, H, Antonenkova, N, Armasu, SM, Baglietto, L, Bandera, EV, Beckmann, MW, Birrer, MJ, Bloom, G, Bogdanova, N, Brenton, JD, Brinton, LA, Brooks-Wilson, A, Brown, R, Butzow, R, Campbell, I, Carney, ME, Carvalho, RS, Chang-Claude, J, Chen, YA, Chen, Z, Chow, WH, Cicek, MS, Coetzee, G, Cook, LS, Cramer, DW, Cybulski, C, Dansonka-Mieszkowska, A, Despierre, E, Doherty, JA, Dörk, T, Du Bois, A, Dürst, M, Eccles, D, Edwards, R, Ekici, AB, Fasching, PA, Fenstermacher, D, Flanagan, J, Gao, YT, Garcia-Closas, M, Gentry-Maharaj, A, Giles, G, Gjyshi, A, Gore, M, Gronwald, J, Guo, Q, Halle, MK, Harter, P, Hein, A, Heitz, F, Hillemanns, P, Hoatlin, M, Høgdall, E, Høgdall, CK, Hosono, S, Jakubowska, A, Jensen, A, Kalli, KR, Karlan, BY

Publikováno v: Pharoah, PDP; Tsai, YY; Ramus, SJ; Phelan, CM; Goode, EL; Lawrenson, K; et al.(2013). GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. Nature Genetics, 45(4), 362-370. doi: 10.1038/ng.2564. UCLA: Retrieved from: http://www.escholarship.org/uc/item/6w2718f0

Genome-wide association studies (GWAS) have identified four susceptibility loci for epithelial ovarian cancer (EOC), with another two suggestive loci reaching near genome-wide significance. We pooled data from a GWAS conducted in North America with a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::4c9795fd27ae3a1ad581c170ee1ec1c4
http://www.escholarship.org/uc/item/6w2718f0

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31

Autor: Permuth-Wey, Jennifer, Lawrenson, K, Shen, HC, Velkova, A, Tyrer, JP, Chen, ZH, Lin, HY, Chen, YA, Tsai, YY, Qu, XT, Ramus, SJ, Karevan, R, Lee, J, Lee, N, Larson, MC, Aben, KK, Anton-Culver, H, Antonenkova, N, Antoniou, AC, Armasu, SM, Bacot, F, Baglietto, L, Bandera, EV, Barnholtz-Sloan, J, Beckmann, MW, Birrer, MJ, Bloom, G, Bogdanova, N, Brinton, LA, Brooks-Wilson, A, Brown, R, Butzow, R, Cai, QY, Campbell, I, Chang-Claude, J, Chanock, S, Chenevix-Trench, G, Cheng, JQ, Cicek, MS, Coetzee, GA, Cook, LS, Couch, FJ, Cramer, DW, Cunningham, JM, Dansonka-Mieszkowska, A, Despierre, E, Doherty, JA, Dork, T, du Bois, A, Durst, M, Easton, DF, Eccles, D, Edwards, R, Ekici, AB, Fasching, PA, Fenstermacher, DA, Flanagan, JM, Garcia-Closas, M, Gentry-Maharaj, A, Giles, GG, Glasspool, RM, Gonzalez-Bosquet, J, Goodman, MT, Gore, M, Gorski, B, Gronwald, J, Hall, P, Halle, Mari Kyllesø, Harter, P, Heitz, F, Hillemanns, P, Hoatlin, M, Hogdall, CK, Hogdall, E, Hosono, S, Jakubowska, A, Jensen, A, Jim, H, Kalli, KR, Karlan, BY, Kaye, SB, Kelemen, LE, Kiemeney, LA, Kikkawa, F, Konecny, GE, Krakstad, Camilla, Kjaer, SK, Kupryjanczyk, J, Lambrechts, D, Lambrechts, S, Lancaster, JM, Le, ND, Leminen, A, Levine, DA, Liang, D, Lim, BK, Lin, J, Lissowska, J, Lu, KH, Lubinski, J, Lurie, G, Massuger, LFAG, Matsuo, K, McGuire, V, McLaughlin, JR, Menon, U, Modugno, F, Moysich, KB, Nakanishi, T, Narod, SA, Nedergaard, L, Ness, RB, Nevanlinna, H, Nickels, S, Noushmehr, H, Odunsi, K, Olson, SH, Orlow, I, Paul, J, Pearce, CL, Pejovic, T, Pelttari, LM, Pike, MC, Poole, EM, Raska, P, Renner, SP, Risch, HA, Rodriguez-Rodriguez, L, Rossing, MA, Rudolph, A, Runnebaum, IB, Rzepecka, IK, Salvesen, Helga Birgitte, Schwaab, I, Severi, G, Shridhar, V, Shu, XO, Shvetsov, YB, Sieh, W, Song, HL, Southey, MC, Spiewankiewicz, B, Stram, D, Sutphen, R, Teo, SH, Terry, KL, Tessier, DC, Thompson, PJ, Tworoger, SS, van Altena, AM, Vergote, I, Vierkant, RA, Vincent, D, Vitonis, AF, Wang-Gohrke, S, Weber, RP, Wentzensen, N, Whittemore, AS, Wik, Elisabeth, Wilkens, LR, Winterhoff, B, Woo, YL, Wu, AH, Xiang, YB, Yang, HP, Zheng, W, Ziogas, A, Zulkifli, F, Phelan, CM, Iversen, E, Schildkraut, JM, Berchuck, A, Fridley, BL, Goode, EL, Pharoah, PDP, Monteiro, ANA, Sellers, TA, Gayther, SA

Externí odkaz: https://hdl.handle.net/1956/12396

Do interactions between SNCA, MAPT, and LRRK2 genes contribute to Parkinson's disease susceptibility?

Autor: Biernacka JM (AUTHOR), Armasu SM (AUTHOR), Cunningham JM (AUTHOR), Eric Ahlskog J (AUTHOR), Chung SJ (AUTHOR), Maraganore DM (AUTHOR), Biernacka, Joanna M¹ (AUTHOR), Armasu, Sebastian M (AUTHOR), Cunningham, Julie M (AUTHOR), Ahlskog, J Eric (AUTHOR), Chung, Sun Ju (AUTHOR), Maraganore, Demetrius M (AUTHOR)

Publikováno v: Parkinsonism & Related Disorders. Dec2011, Vol. 17 Issue 10, p730-736. 7p.

Methylation Signature Implicated in Immuno-Suppressive Activities in Tubo-Ovarian High-Grade Serous Carcinoma.

Autor: Wang C; Division of Computational Biology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota., Block MS; Department of Oncology, Mayo Clinic, Rochester, Minnesota., Cunningham JM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota., Sherman ME; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Florida., McCauley BM; Division of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota., Armasu SM; Division of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota., Vierkant RA; Division of Computational Biology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota., Traficante N; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Talhouk A; British Columbia's Ovarian Cancer Research (OVCARE) Program, BC Cancer, Vancouver General Hospital, and University of British Columbia, Vancouver, BC, Canada.; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada., Ramus SJ; School of Clinical Medicine, Faculty of Medicine, University of NSW Sydney, Sydney, New South Wales, Australia.; Adult Cancer Program, Lowy Cancer Research Centre, University of NSW Sydney, Sydney, New South Wales, Australia., Pejovic N; St Louis School of Medicine, St. Louis, Missouri., Köbel M; Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada., Jorgensen BD; Division of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota., Garsed DW; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Fereday S; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Doherty JA; Department of Population Health Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah., Ariyaratne D; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Anglesio MS; British Columbia's Ovarian Cancer Research (OVCARE) Program, BC Cancer, Vancouver General Hospital, and University of British Columbia, Vancouver, BC, Canada.; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., Widschwendter M; European Translational Oncology Prevention and Screening (EUTOPS) Institute, Universität Innsbruck, Hall, Tirol, Austria., Pejovic T; Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon.; Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon., Bosquet JG; Division of Gynecologic Oncology, Department of Obstetrics and Gynecologic, University of Iowa, Iowa City, Iowa., Bowtell DD; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Winham SJ; Division of Computational Biology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota., Goode EL; Division of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota.

Publikováno v: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology [Cancer Epidemiol Biomarkers Prev] 2023 Apr 03; Vol. 32 (4), pp. 542-549.