Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Armando M. De Palma"'
Autor:
Armando M. De Palma, Gerhard Pürstinger, Eva Wimmer, Amy K. Patick, Koen Andries, Bart Rombaut, Erik De Clercq, Johan Neyts
Publikováno v:
Emerging Infectious Diseases, Vol 14, Iss 4, Pp 545-551 (2008)
In 1988, the World Health Assembly launched the Global Polio Eradication Initiative, which aimed to use large-scale vaccination with the oral vaccine to eradicate polio worldwide by the year 2000. Although important progress has been made, polio rema
Externí odkaz:
https://doaj.org/article/18802426a8f54f95b6c17dc8ed0851d3
Autor:
Lonneke van der Linden, Laia Vives-Adrián, Barbara Selisko, Cristina Ferrer-Orta, Xinran Liu, Kjerstin Lanke, Rachel Ulferts, Armando M De Palma, Federica Tanchis, Nesya Goris, David Lefebvre, Kris De Clercq, Pieter Leyssen, Céline Lacroix, Gerhard Pürstinger, Bruno Coutard, Bruno Canard, David D Boehr, Jamie J Arnold, Craig E Cameron, Nuria Verdaguer, Johan Neyts, Frank J M van Kuppeveld
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004733 (2015)
The genus Enterovirus of the family Picornaviridae contains many important human pathogens (e.g., poliovirus, coxsackievirus, rhinovirus, and enterovirus 71) for which no antiviral drugs are available. The viral RNA-dependent RNA polymerase is an att
Externí odkaz:
https://doaj.org/article/184861f7dc7545d98c08e695d7ff897c
Autor:
Alain Sarasin, Cécile Ged, Said Aoufouchi, Caroline Pouvelle, Armando M. De Palma, Marie-Anne Morren, Alain Taieb
Publikováno v:
American Journal of Medical Genetics Part A. 173:2511-2516
We describe the characterization of Xeroderma Pigmentosum variant (XPV) in a young Caucasian patient with phototype I, who exhibited a high sensitivity to sunburn and multiple cutaneous tumors at the age of 15 years. Two novel mutations in the POLH g
Autor:
David Franco, Céline Lacroix, Armando M. De Palma, Mark Decramer, Johan Neyts, Hendrik Jan Thibaut
Publikováno v:
Reviews in Medical Virology. 26:21-33
Chronic obstructive pulmonary disease (COPD) is a life-threatening lung illness characterized by persistent and progressive airflow limitation. Exacerbations of COPD contribute to the severity of this pathology and accelerate disease progression. To
Publikováno v:
Contact Dermatitis. 73:130-132
Keywords: allergic contact dermatitis; anti-ageing; cosmetics; Magnolia officinalis bark extract; Magnoliaceae; patch tests; plants
Publikováno v:
Methods in Molecular Biology ISBN: 9781493932917
The Global Polio Eradication Initiative, launched in 1988, had as its goal the eradication of polio worldwide by the year 2000 through large-scale vaccinations campaigns with the live attenuated oral PV vaccine (OPV) (Griffiths et al., Biologicals 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4822b49dcf1fccc5e3d2492b352effe0
https://doi.org/10.1007/978-1-4939-3292-4_17
https://doi.org/10.1007/978-1-4939-3292-4_17
Autor:
Pieter Leyssen, Martin Dračínský, Johan Neyts, Hubert Hřebabecký, Milan Dejmek, Michal Šála, Radim Nencka, Armando M. De Palma
Publikováno v:
Bioorganic & Medicinal Chemistry Letters; Vol 22
We report on the synthesis and the study of the structure–activity relationship of novel 9-norbornyl-6-chloropurine derivatives, which exert selective antiviral activity on the replication of Coxsackievirus B3. In particular, the synthetic approach
Autor:
Milan Dejmek, Michal Šála, Pieter Leyssen, Martin Dračínský, Hubert Hřebabecký, Helena Mertlíková-Kaiserová, Radim Nencka, Armando M. De Palma, Johan Neyts
Publikováno v:
Bioorganic & Medicinal Chemistry Letters; Vol 21
Coxsackievirus and related enteroviruses are important human pathogens that cause various diseases with clinical manifestations ranging from trivial flu-like syndromes to dangerous or even fatal diseases such as myocarditis, meningitis and encephalit
Autor:
Hubert Hřebabecký, Radim Nencka, Pieter Leyssen, Johan Neyts, Antonín Holý, Armando M. De Palma, Martin Dračínský, Michal Šála
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:4374-4384
The synthesis and SAR study of a novel class of coxsackievirus B3 (CVB3) inhibitors are reported. These compounds could be considered as the 6-chloropurines substituted at position 9 with variously substituted bicyclic scaffolds (bicyclo[2.2.1]heptan
Autor:
Michal Šála, Johan Neyts, Milena Masojídková, Antonín Holý, Hubert Hřebabecký, Martin Dračínský, Armando M. De Palma
Publikováno v:
Collection of Czechoslovak Chemical Communications. 75:1-20
Novel class of the carbocyclic nucleosides based on bicyclo[2.2.1]heptene/heptane was prepared by two approaches. Thymine analogues were synthesized starting from methyl (1R*,4S*)-bicyclo[2.2.1]hepta-2,5-diene-2-carboxylate1by Michael addition of the