Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Armando Lira Pineda"'
Autor:
Mikhail Zaslavskiy, Armando Lira Pineda, David Dellamonica, Adrien Rousset, Robert P. Giugliano, Marc S. Sabatine, Romuald Menuet, Paul Trichelair, L. Ricci
Publikováno v:
European Heart Journal - Digital Health. 3:38-48
Aims Through this proof of concept, we studied the potential added value of machine learning (ML) methods in building cardiovascular risk scores from structured data and the conditions under which they outperform linear statistical models. Methods an
Autor:
Chung-Wah Siu, Peter S. Sever, Robert P. Giugliano, John Amerena, Donghoon Choi, Armando Lira Pineda, Prakash Deedwania, Min-Ji Charng, Terje R. Pedersen, Anthony C Keech, Leslie Tay, Marc S. Sabatine, Vijay K. Chopra, Chen Lu, Kazuma Oyama, Atsushi Hirayama, Wan Azman Wan Ahmad, Sabina A. Murphy, Minao Tang
Publikováno v:
Circulation Journal. 85:2063-2070
BACKGROUND There are concerns that Asian patients respond differently to some medications. This study evaluated the efficacy and safety of evolocumab among Asian vs. other subjects in the FOURIER trial, which randomized stable atherosclerosis patient
Autor:
Petr Jarolim, Marc S. Sabatine, Nicholas A Marston, Huei Wang, Anthony C Keech, David A. Morrow, Minao Tang, Kazuma Oyama, Robert P. Giugliano, Peter S. Sever, Armando Lira Pineda
Publikováno v:
Circulation. 144:249-251
Autor:
Marc S. Sabatine, Huei Wang, Terje R. Pedersen, Frederick K. Kamanu, Anthony C Keech, Yared Gurmu, Francesco Nordio, Nicholas A Marston, Steven A. Lubitz, Carolina Roselli, Christian T. Ruff, Robert P. Giugliano, Patrick T. Ellinor, Peter S. Sever, Armando Lira Pineda
Publikováno v:
Circulation
Circulation, 141(8), 616-623. LIPPINCOTT WILLIAMS & WILKINS
Circulation, 141(8), 616-623. LIPPINCOTT WILLIAMS & WILKINS
Background: The ability of a genetic risk score to predict risk in established cardiovascular disease and identify individuals who derive greater benefit from PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibition has not been established.
Autor:
Philippe Gabriel Steg, Deepak L. Bhatt, Michael Miller, Eliot A. Brinton, Terry A. Jacobson, Steven Ketchum, Lixia Jiao, Armando Lira Pineda, Ralph T. Doyle, Jean Claude Tardif, Christie M. Ballantyne
Publikováno v:
Journal of the American College of Cardiology. 81:1113
Autor:
Prakash Deedwania, David M. Charytan, Scott M. Wasserman, Terje R. Pedersen, Robert Giugliano, Anders G. Olsson, J-G Park, Sabatine, Anthony Keech, Peter S. Sever, Armando Lira Pineda
Publikováno v:
Journal of the American College of Cardiology. 74:1162-1166
Autor:
Nicholas A Marston, Seung Hoan Choi, Marc S. Sabatine, Anthony C Keech, Christian T. Ruff, Huei Wang, Patrick T. Ellinor, Frederick K. Kamanu, Robert P. Giugliano, Giorgio E. M. Melloni, Steven A. Lubitz, James P. Pirruccello, Peter S. Sever, Armando Lira Pineda, Anthony A. Philippakis
Publikováno v:
Circulation. 142
Introduction: Patients with loss of function (LoF) mutations of the LDL receptor gene (LDLR) have lifelong elevations in LDL-C. We investigated their risk of cardiovascular (CV) events compared with patients with intact LDLR function. Methods: We per
Autor:
Anthony C Keech, Marc S. Sabatine, Petr Jarolim, David A. Morrow, Robert P. Giugliano, Huei Wang, Minao Tang, Peter S. Sever, Armando Lira Pineda, Kazuma Oyama, Nicholas A Marston
Publikováno v:
Circulation. 142
Introduction: The 2018 AHA/ACC cholesterol guidelines only recommend PCSK9 inhibitors in patients with very high risk ASCVD. However, high-sensitivity troponin (hsTn) can reclassify some lower risk patients as very high risk, identifying a subgroup w
Autor:
Narimon Honarpour, Marc S. Sabatine, Anthony C Keech, Terje R. Pedersen, Sabina A. Murphy, Scott M. Wasserman, Jeffrey L. Saver, Peter S. Sever, Armando Lira Pineda, Robert P. Giugliano, Huei Wang, Erin A. Bohula
Publikováno v:
Stroke. 51(5)
Background and Purpose— The PCSK9 (proprotein convertase subtilisin-kexin type 9) monoclonal antibody evolocumab lowered LDL (low-density lipoprotein) cholesterol by 59% to 0.8 (0.5–1.2) mmol/L and significantly reduced major vascular events in t
Autor:
Gaetano M. De Ferrari, Basil S. Lewis, Prakash Deedwania, Stephen D. Wiviott, Lawrence A. Leiter, Terje R. Pedersen, Julia F Kuder, Narimon Honarpour, Robert P. Giugliano, Anthony C Keech, Sabina A. Murphy, Peter S. Sever, Armando Lira Pineda, Yehuda Handelsman, Ioanna Gouni-Berthold, Marc S. Sabatine
Publikováno v:
The Lancet Diabetes & Endocrinology. 5:941-950
Summary Background The proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor evolocumab reduced LDL cholesterol and cardiovascular events in the FOURIER trial. In this prespecified analysis of FOURIER, we investigated the efficacy and safet