Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Armando G. Salinas"'
Autor:
Armando G. Salinas, Jeong Oen Lee, Shana M. Augustin, Shiliang Zhang, Tommaso Patriarchi, Lin Tian, Marisela Morales, Yolanda Mateo, David M. Lovinger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The development of genetically encoded dopamine sensors such as dLight has provided a new approach to measuring slow and fast dopamine dynamics both in brain slices and in vivo, possibly enabling dopamine measurements in areas like the dorso
Externí odkaz:
https://doaj.org/article/00c2d19f80214233be1c3432d94f4dc6
Autor:
Zhenhua Liu, Nannan Yang, Jie Dong, Wotu Tian, Lisa Chang, Jinghong Ma, Jifeng Guo, Jieqiong Tan, Ao Dong, Kaikai He, Jingheng Zhou, Resat Cinar, Junbing Wu, Armando G. Salinas, Lixin Sun, Mantosh Kumar, Breanna T. Sullivan, Braden B. Oldham, Vanessa Pitz, Mary B. Makarious, Jinhui Ding, Justin Kung, Chengsong Xie, Sarah L. Hawes, Lupeng Wang, Tao Wang, Piu Chan, Zhuohua Zhang, Weidong Le, Shengdi Chen, David M. Lovinger, Cornelis Blauwendraat, Andrew B. Singleton, Guohong Cui, Yulong Li, Huaibin Cai, Beisha Tang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
2- arachidonoylglycerol (2-AG), an abundant endocannabinoid in the brain, regulates diverse neural functions. Here, the authors identified four loss-of-function mutations in dicylglycerol lipase β (DAGLB) from six patients with early onset Parkinson
Externí odkaz:
https://doaj.org/article/4a94e3b86d214217aab9a2b47dae2413
Autor:
Armando G. Salinas, Jacob A. Nadel, Yolanda Mateo, Thanh Huynh, Shana M. Augustin, Karel Pacak, David M. Lovinger
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 10994 (2022)
Alcohol use disorder (AUD) is characterized by escalating alcohol consumption, preoccupation with alcohol, and continued alcohol consumption despite adverse consequences. Dopamine has been implicated in neural and behavioral processes involved in rew
Externí odkaz:
https://doaj.org/article/cdb7b76f85424777879a2b570eb9f459
Autor:
Carmelo Sgobio, Junbing Wu, Wang Zheng, Xi Chen, Jing Pan, Armando G. Salinas, Margaret I. Davis, David M. Lovinger, Huaibin Cai
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Aldehyde dehydrogenase 1 (ALDH1A1)–positive dopaminergic (DA) neurons at the ventral substantia nigra pars compacta (SNpc) preferentially degenerate in Parkinson’s disease (PD). Their projection pattern and dopamine release properties, h
Externí odkaz:
https://doaj.org/article/22f6b7d0244845fab143528d5606963b
Autor:
Vikrant R. Mahajan, Jacob A. Nadel, M. Todd King, Robert J. Pawlosky, Margaret I. Davis, Richard L. Veech, David M. Lovinger, Armando G. Salinas
BackgroundParkinson’s disease is a progressive, neurodegenerative disease characterized by motor dysfunction and dopamine deficits. The MitoPark mouse recapitulates several facets of Parkinson’s disease, including gradual development of motor def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd7853a2583008db616bd37735cac652
https://doi.org/10.1101/2022.11.14.516368
https://doi.org/10.1101/2022.11.14.516368
Autor:
Sonja Blumenstock, Jochen Herms, Carmelo Sgobio, Fanfan Sun, Severin Filser, Jose Medina-Luque, Armando G. Salinas
Publikováno v:
Brain Pathology
Brain pathology 32(2), e13036 (2022). doi:10.1111/bpa.13036
Brain pathology 32(2), e13036 (2022). doi:10.1111/bpa.13036
Misfolded alpha-synuclein spreads along anatomically connected areas through the brain, prompting progressive neurodegeneration of the nigrostriatal pathway in Parkinson's disease. To investigate the impact of early stage seeding and spreading of mis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51edb0cf7cd5166ab5359034bce8f792
https://hdl.handle.net/21.11116/0000-0009-988D-D21.11116/0000-0009-988F-B
https://hdl.handle.net/21.11116/0000-0009-988D-D21.11116/0000-0009-988F-B
Autor:
Gwen S. Stinnett, Guoxiang Luo, Verginia C. Cuzon Carlson, Armando G. Salinas, Audrey F. Seasholtz, Yolanda Mateo, David M. Lovinger, Kathleen A. Grant
Publikováno v:
Neuropsychopharmacology
The dorsal striatum (DS) is implicated in behavioral and neural processes including action control and reinforcement. Alcohol alters these processes in rodents, and it is believed that the development of alcohol use disorder involves changes in DS do
Autor:
Armando G. Salinas, Jeong O. Lee, Shana M. Augustin, Shiliang Zhang, Tommaso Patriarchi, Lin Tian, Marisela Morales, Yolanda Mateo, David M. Lovinger
Dopamine produces neuromodulation throughout the basal ganglia, cortex and other brain regions, and is implicated in movement control, neural mechanisms of reward and actions of misused substances. The efferent projections of dopaminergic neurons wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9ff9bc7bc436249f44c215f1ac51cfd
https://doi.org/10.1101/2022.01.09.475513
https://doi.org/10.1101/2022.01.09.475513
Autor:
Zhenhua Liu, Nannan Yang, Jie Dong, Wotu Tian, Lisa Chang, Jinghong Ma, Jifeng Guo, Jieqiong Tan, Ao Dong, Kaikai He, Jingheng Zhou, Resat Cinar, Junbing Wu, Armando G. Salinas, Lixin Sun, Mantosh Kumar, Breanna T. Sullivan, Braden B. Oldham, Vanessa Pitz, Mary B. Makarious, Jinhui Ding, Justin Kung, Chengsong Xie, Sarah L. Hawes, Lupeng Wang, Tao Wang, Piu Chan, Zhuohua Zhang, Weidong Le, Shengdi Chen, David M. Lovinger, Cornelis Blauwendraat, Andrew B. Singleton, Guohong Cui, Yulong Li, Huaibin Cai, Beisha Tang
Publikováno v:
Nature communications. 13(1)
Endocannabinoid (eCB), 2-arachidonoyl-glycerol (2-AG), the most abundant eCB in the brain, regulates diverse neural functions. Here we linked multiple homozygous loss-of-function mutations in 2-AG synthase diacylglycerol lipase β (DAGLB) to an early
Publikováno v:
Neuron. 96:1223-1238
Ethanol is one of the most commonly abused drugs. Although environmental and genetic factors contribute to the etiology of alcohol use disorders, it is ethanol’s actions in the brain that explain (1) acute ethanol-related behavioral changes, such a