Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Armando Cázares-Körner"'
Autor:
Olov Wallner, Armando Cázares‐Körner, Emma Rose Scaletti, Geoffrey Masuyer, Tove Bekkhus, Torkild Visnes, Kirill Mamonov, Florian Ortis, Thomas Lundbäck, Maria Volkova, Tobias Koolmeister, Elisée Wiita, Olga Loseva, Monica Pandey, Evert Homan, Carlos Benítez‐Buelga, Jonathan Davies, Martin Scobie, Ulrika Warpman Berglund, Christina Kalderén, Pål Stenmark, Thomas Helleday, Maurice Michel
Publikováno v:
ChemMedChem. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2057798a6f1ce2cc79a2bd7cf5f16fc
https://doi.org/10.1002/cmdc.202200681
https://doi.org/10.1002/cmdc.202200681
Autor:
Olov Wallner, Armando Cázares‐Körner, Emma Rose Scaletti, Geoffrey Masuyer, Tove Bekkhus, Torkild Visnes, Kirill Mamonov, Florian Ortis, Thomas Lundbäck, Maria Volkova, Tobias Koolmeister, Elisée Wiita, Olga Loseva, Monica Pandey, Evert Homan, Carlos Benítez‐Buelga, Jonathan Davies, Martin Scobie, Ulrika Warpman Berglund, Christina Kalderén, Pål Stenmark, Thomas Helleday, Maurice Michel
Publikováno v:
ChemMedChem
8-oxo Guanine DNA Glycosylase 1 is the initiating enzyme within base excision repair and removes oxidized guanines from damaged DNA. Since unrepaired 8-oxoG could lead to G : C→T : A transversion, base removal is of utmost importance for cells to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9cd2d96f25f6a4c11257c011d10baf
https://doi.org/10.1002/cmdc.202200310
https://doi.org/10.1002/cmdc.202200310
Autor:
Saeed Eshtad, Ingrid Almlöf, Pål Stenmark, Matthieu Desroses, Armando Cázares-Körner, Evert Homan, Mikael Altun, Azita Rasti, Si Min Zhang, Torsten Schaller, Lars Bräutigam, Hanna Axelsson, Megan Carter, Adam Throup, Rosa Krimpenfort, Tobias Koolmeister, Daniel Rehling, Ann-Sofie Jemth, Thomas Lundbäck, Elisee Wiita, Thomas Helleday, Anna Hagenkort, Brent D. G. Page, Martin Scobie, Ulrika Warpman Berglund, Linda Pudelko, Antonio Sarno, Andreas Krämer, Christina Kalderén, Juliane Kutzner, Olov A. Wallner, Shruti Regmi, Mona Göttmann, Sean G. Rudd, Nicholas C.K. Valerie, Stefan Knapp, Olga Loseva
Publikováno v:
Nature chemical biology
Nature Chemical Biology
Nature Chemical Biology
The NUDIX hydrolase NUDT15 was originally implicated in sanitizing oxidized nucleotides but was later shown to hydrolyze the active thiopurine metabolites, 6-thio-(d)GTP, thereby dictating the clinical response of this standard-of-care treatment for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c67aef4c81a65cb8722945b628f211
http://europepmc.org/articles/PMC7610571
http://europepmc.org/articles/PMC7610571
Autor:
Roberto Icken Hernández López, Armando Cázares-Körner, Paul A. Dalby, David Steadman, Daniel Méndez-Sánchez, Helen C. Hailes, Haoran Yu, Tom D. Sheppard, Sally Higson, John M. Ward
Publikováno v:
The FEBS Journal. 287:1758-1776
A narrow substrate range is a major limitation in exploiting enzymes more widely as catalysts in synthetic organic chemistry. For enzymes using two substrates, the simultaneous optimisation of both substrate specificities is also required for the rap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98884f7d3d784d83a586f00766c2f99
https://doi.org/10.1111/febs.15108
https://doi.org/10.1111/febs.15108
Autor:
Christina Kalderén, Maurice Michel, Olov A. Wallner, Geoffrey Masuyer, Oliver Mortusewicz, Carlos Benitez-Buelga, Armando Cázares-Körner, Ann-Sofie Jemth, Thomas Helleday, Kumar Sanjiv, Bishoy M. F. Hanna, Olga Loseva, Pål Stenmark, Torkild Visnes, Ulrika Warpman Berglund
Publikováno v:
Proceedings of The 1st International Electronic Conference on Cancers: Exploiting Cancer Vulnerability by Targeting the DNA Damage Response.
Due to oncogene expression and altered metabolism, reactive oxygen species (ROS) production is augmented in cancer cells resulting in oxidative DNA damage. 8‑oxoguanine (8-oxoG) is one of the most abundant oxidative DNA lesions. This premutagenic l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5cb537a489d65ace2913a618d25ac60
https://doi.org/10.3390/iecc2021-09213
https://doi.org/10.3390/iecc2021-09213
Publikováno v:
Nucleic Acids Research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::1b96a4787958dae3873632e7ad65a12f
Autor:
Roberto Icken Hernández López, Sally Higson, Armando Cázares-Körner, Daniel Méndez-Sánchez, David Steadman, John M. Ward, Helen C. Hailes, Haoran Yu, Paul A. Dalby
A narrow substrate range is a major limitation in exploiting enzymes more widely as catalysts in synthetic organic chemistry. For enzymes using two substrates, the simultaneous optimization of both substrate specificities, is also required for the ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f64b170f47bddbdff75757c9aca969
https://doi.org/10.1101/719906
https://doi.org/10.1101/719906
Autor:
Torkild Visnes, Armando Cázares-Körner, Carlos Benitez-Buelga, Maurice Grube, Thomas Helleday, Bishoy M. F. Hanna
Publikováno v:
DNA Repair
Base excision repair (BER) repairs mutagenic or genotoxic DNA base lesions, thought to be important for both the etiology and treatment of cancer. Cancer phenotypic stress induces oxidative lesions, and deamination products are responsible for one of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e106e94953496cf5d8b824caa4160567
Autor:
Camilla Göktürk, Elisee Wiita, Olga Loseva, Oliver Mortusewicz, Armando Cázares-Körner, Per Artursson, Aleksandr Manoilov, Mikael Altun, Petar Iliev, Ann-Sofie Jemth, Dag Ivanic, Annika Jenmalm Jensen, Roman A. Zubarev, Evert Homan, Azita Rasti, Thomas Helleday, Lang Pan, Istvan Boldogh, Catharina Von Nicolai, Carlos Benitez-Buelga, Tobias Koolmeister, Wenjing Hao, Pawel Baranczewski, Martin Scobie, Bishoy M. F. Hanna, Therese Pham, Ulrika Warpman Berglund, Stella Karsten, Cynthia B.J. Paulin, Geoffrey Masuyer, Antonio Sarno, Pål Stenmark, Torkild Visnes, Juan Astorga-Wells, Christina Kalderén, Olov A. Wallner, Kumar Sanjiv, Xueqing Ba, Maurice Grube, Hans E. Krokan
Publikováno v:
Science
DNA binding as an anti-inflammatory Mice that lack the gene encoding 8-oxoguanine DNA glycosylase 1 (OGG1) show resistance to inflammation. This enzyme binds to sites of oxidative DNA damage and initiates DNA base excision repair. Visnes et al. devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ccdba340149cf0ea8e5f4b68a6c3a36
https://hdl.handle.net/11250/2577000
https://hdl.handle.net/11250/2577000
Autor:
Marie-Caroline Jacques-Cordonnier, Sabin Llona-Minguez, Armando Cázares-Körner, Martin Scobie, Sylvain A. Jacques, Thomas Helleday, Matthieu Desroses, Tobias Koolmeister
Publikováno v:
Tetrahedron Letters. 54:3554-3557
This Letter describes a convenient, efficient, and clean synthesis of various tetrahydro-β-carbolines catalyzed by propane phosphonic acid anhydride T3P® under microwave irradiation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5c9639dca6250d7f14dbfae8a9c78b9
https://doi.org/10.1016/j.tetlet.2013.04.107
https://doi.org/10.1016/j.tetlet.2013.04.107