Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Arman W. Mohammad"'
Autor:
Christina Galonska, Jocelyn Charlton, Alexandra L. Mattei, Julie Donaghey, Kendell Clement, Hongcang Gu, Arman W. Mohammad, Elena K. Stamenova, Davide Cacchiarelli, Sven Klages, Bernd Timmermann, Tobias Cantz, Hans R. Schöler, Andreas Gnirke, Michael J. Ziller, Alexander Meissner
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Catalytically inactive Cas9 fused to a methyltransferase has emerged as a promising epigenome modifying tool. Here the authors generate a methylation depleted but maintenance competent mouse ES cell line and find ubiquitous off-target activity.
Externí odkaz:
https://doaj.org/article/facfcb998fb94a91ab5dd5199cd3a1b4
Autor:
Marco A Coelho, Márcia David-Palma, Terrance Shea, Katharine Bowers, Sage McGinley-Smith, Arman W Mohammad, Andreas Gnirke, Andrey M Yurkov, Minou Nowrousian, Sheng Sun, Christina A Cuomo, Joseph Heitman
Publikováno v:
PLoS Biology, Vol 22, Iss 6, p e3002682 (2024)
In exploring the evolutionary trajectories of both pathogenesis and karyotype dynamics in fungi, we conducted a large-scale comparative genomic analysis spanning the Cryptococcus genus, encompassing both global human fungal pathogens and nonpathogeni
Externí odkaz:
https://doaj.org/article/7d4fb4fbff1a4c5cbc0badce4e9fce91
Autor:
Alexander Meissner, Catherine J. Wu, Andreas Gnirke, Elias Campo, Thomas J. Kipps, Bernd Timmermann, Sven Klages, Donna S. Neuberg, Kenneth J. Livak, Shuqiang Li, Lili Wang, Jennifer R. Brown, Stacey M. Fernandes, Neil E. Kay, Tait D. Shanafelt, Esteban Braggio, Susan L. Slager, Connie Lesnick, Arman W. Mohammad, Laura Rassenti, Hongcang Gu, Michaela Gruber, Kendell Clement, Camilla K. Lemvigh, Noelia Purroy, Anat Biran, Helene Kretzmer
Non-uniform dynamics of single CpGs among CLL progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb264cc5bd8785cc56f7f7df4a4aa51c
https://doi.org/10.1158/2643-3230.22542277
https://doi.org/10.1158/2643-3230.22542277
Autor:
Alexander Meissner, Catherine J. Wu, Andreas Gnirke, Elias Campo, Thomas J. Kipps, Bernd Timmermann, Sven Klages, Donna S. Neuberg, Kenneth J. Livak, Shuqiang Li, Lili Wang, Jennifer R. Brown, Stacey M. Fernandes, Neil E. Kay, Tait D. Shanafelt, Esteban Braggio, Susan L. Slager, Connie Lesnick, Arman W. Mohammad, Laura Rassenti, Hongcang Gu, Michaela Gruber, Kendell Clement, Camilla K. Lemvigh, Noelia Purroy, Anat Biran, Helene Kretzmer
Table of correlation between time points within one sample and number of hyper- or hypomethylated CpGs for all CLL (top) and naïve and memory B cell samples (bottom)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a60c5fa8fe9ac2c439fffb59f48c2a
https://doi.org/10.1158/2643-3230.22542256.v1
https://doi.org/10.1158/2643-3230.22542256.v1
Autor:
Alexander Meissner, Catherine J. Wu, Andreas Gnirke, Elias Campo, Thomas J. Kipps, Bernd Timmermann, Sven Klages, Donna S. Neuberg, Kenneth J. Livak, Shuqiang Li, Lili Wang, Jennifer R. Brown, Stacey M. Fernandes, Neil E. Kay, Tait D. Shanafelt, Esteban Braggio, Susan L. Slager, Connie Lesnick, Arman W. Mohammad, Laura Rassenti, Hongcang Gu, Michaela Gruber, Kendell Clement, Camilla K. Lemvigh, Noelia Purroy, Anat Biran, Helene Kretzmer
Supplementary Figures 1-7 and matching legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052b420a6633dd0b86f90c667ce83a5c
https://doi.org/10.1158/2643-3230.22542265
https://doi.org/10.1158/2643-3230.22542265
Autor:
Alexander Meissner, Catherine J. Wu, Andreas Gnirke, Elias Campo, Thomas J. Kipps, Bernd Timmermann, Sven Klages, Donna S. Neuberg, Kenneth J. Livak, Shuqiang Li, Lili Wang, Jennifer R. Brown, Stacey M. Fernandes, Neil E. Kay, Tait D. Shanafelt, Esteban Braggio, Susan L. Slager, Connie Lesnick, Arman W. Mohammad, Laura Rassenti, Hongcang Gu, Michaela Gruber, Kendell Clement, Camilla K. Lemvigh, Noelia Purroy, Anat Biran, Helene Kretzmer
Most human cancers converge to a deregulated methylome with reduced global levels and elevated methylation at select CpG islands. To investigate the emergence and dynamics of the cancer methylome, we characterized genome-wide DNA methylation in prene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0465fb04b233bbc5e5b4e45d434aa6
https://doi.org/10.1158/2643-3230.c.6549850
https://doi.org/10.1158/2643-3230.c.6549850
Autor:
Laura Z. Rassenti, Elisa Ten Hacken, Arman W. Mohammad, Eugen Tausch, Lili Wang, Mohamed Uduman, Jennifer R. Brown, Ruben D. Carrasco, Andreas Gnirke, Stacey M. Fernandes, Shanye Yin, Elizabeth Witten, Clare Sun, Catherine J. Wu, Alexander Meissner, Nathan J Dangle, Catherine Gutierrez, Fara Faye Regis, Gabriela Brunsting Hoffmann, Fabienne Lucas, Thomas J. Kipps, Kristen E. Stevenson, Donna Neuberg, Anthony Letai, Jon C. Aster, Anat Biran, Stephan Stilgenbauer, Salma Parvin, Mei Zheng, Helene Kretzmer, Leah Billington
Publikováno v:
Cancer Res
Cancer research, vol 81, iss 24
Cancer research, vol 81, iss 24
Chronic lymphocytic leukemia (CLL) is characterized by disordered DNA methylation, suggesting these epigenetic changes might play a critical role in disease onset and progression. The methyltransferase DNMT3A is a key regulator of DNA methylation. Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb83f15b36b42704965ca7bce54e9f73
https://europepmc.org/articles/PMC8678341/
https://europepmc.org/articles/PMC8678341/
Autor:
Kendell Clement, Camilla K. Lemvigh, Michaela Gruber, Andreas Gnirke, Laura Z. Rassenti, Anat Biran, Arman W. Mohammad, Donna Neuberg, Kenneth J. Livak, Catherine J. Wu, Neil E. Kay, Jennifer R. Brown, Thomas J. Kipps, Connie Lesnick, Helene Kretzmer, Shuqiang Li, Lili Wang, Bernd Timmermann, Stacey M. Fernandes, Noelia Purroy, Sven Klages, Susan L. Slager, Esteban Braggio, Tait D. Shanafelt, Elias Campo, Hongcang Gu, Alexander Meissner
Publikováno v:
Blood cancer discovery, vol 2, iss 1
Blood Cancer Discov
Blood Cancer Discovery
Blood Cancer Discov
Blood Cancer Discovery
Most human cancers converge to a deregulated methylome with reduced global levels and elevated methylation at select CpG islands. To investigate the emergence and dynamics of the cancer methylome, we characterized genome-wide DNA methylation in prene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c22b79634605866c9bdfd397734ff7b
https://escholarship.org/uc/item/95n8m52f
https://escholarship.org/uc/item/95n8m52f
Autor:
Pavan Bachireddy, Nathan Mathewson, Samuel S. Freeman, Arman W. Mohammad, Nikolaos Barkas, Donna Neuberg, Gad Getz, Natalie Bavli, Kendell Clement, Juliet Forman, Jennifer R. Brown, Thomas J. Kipps, Liudmila Elagina, Christina Ennis, Vincent T. Ho, Sachet A. Shukla, Edwin P. Alyea, Jerome Ritz, Robert J. Soiffer, Ignaty Leshchiner, Laura Z. Rassenti, Catherine J. Wu, Vinhkhang N Nguyen, Derin B. Keskin, Peter V. Kharchenko, Andreas Gnirke, Satyen H. Gohil
Publikováno v:
Science translational medicine, vol 12, iss 561
Sci Transl Med
Sci Transl Med
Leukemic relapse remains a major barrier to successful allogeneic hematopoietic stem cell transplantation (allo-HSCT) for aggressive hematologic malignancies. The basis for relapse of advanced lymphoid malignancies remains incompletely understood and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5536a2cf37addc9c92e0cc331a2c012
https://doi.org/10.1126/scitranslmed.abb7661
https://doi.org/10.1126/scitranslmed.abb7661
Autor:
Jennifer R. Brown, Robert J. Soiffer, Christina Ennis, Gad Getz, Kendell Clement, Liudmila Elagina, Andreas Gnirke, Jerome Ritz, Peter V. Kharchenko, Edwin P. Alyea, Nikolas Barkas, Sachet A. Shukla, Samuel S. Freeman, Juliet Forman, Arman W. Mohammad, Laura Z. Rassenti, Satyen H. Gohil, Ignaty Leshchiner, Donna Neuberg, Thomas J. Kipps, Vincent T. Ho, Pavan Bachireddy, Vinhkhang N Nguyen, Catherine J. Wu, Natalie Bavli
Resistance to the graft-versus-leukemia (GvL) effect remains the major barrier to successful allogeneic hematopoietic stem cell transplantation (allo-HSCT) for aggressive hematologic malignancies. The basis of GvL resistance for advanced lymphoid mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3edd93b483a303c01b765304236be70
https://doi.org/10.1101/2020.04.09.033555
https://doi.org/10.1101/2020.04.09.033555