Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Arman Nayebosadri"'
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Mechanosensation by biological membranes can be relayed by mechanical tension to ion channels. Here the authors show that phospholipase D (PLD) is activated by mechanical disruption of lipid rafts which allows PLD to mix with its substrate in the lip
Externí odkaz:
https://doaj.org/article/ef25fc0a4a2e402685b431a30b4dbb41
Publikováno v:
SSRN Electronic Journal.
The transduction of force to a biological signal is critical to all living organisms and cells. Mechanosensitive ion channels participate, but the biophysical mechanism that transduces force remains unclear. Here we show that the sensing of membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a9f3641350cd096af7c8d4153e809b7
https://doi.org/10.2139/ssrn.3155650
https://doi.org/10.2139/ssrn.3155650
Publikováno v:
Annals of Biomedical Engineering. 40:1508-1519
Endothelial cells are continuously exposed to hemodynamic shear stress, which has been shown to induce an array of physiological responses at the cellular and molecular levels. Uniform high shear stress is protective against vascular diseases such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e75936926f9bb21a122d513cd86a55a
https://doi.org/10.1007/s10439-011-0499-7
https://doi.org/10.1007/s10439-011-0499-7
Autor:
Julie Y. Ji, Arman Nayebosadri
Publikováno v:
American journal of physiology. Cell physiology. 305(3)
The lamina serves to maintain the nuclear structure and stiffness while acting as a scaffold for heterochromatin and many transcriptional proteins. Its role in endothelial mechanotransduction, specifically how nuclear mechanics impact gene regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4606caecf817a36ec94e3a6761b8dfc
https://pubmed.ncbi.nlm.nih.gov/23703529
https://pubmed.ncbi.nlm.nih.gov/23703529