Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Arman, Kulyyassov"'
Autor:
Aizhan Akhmadi, Adilkhan Yeskendir, Nelly Dey, Arman Mussakhmetov, Zariat Shatkenova, Arman Kulyyassov, Anna Andreeva, Darkhan Utepbergenov
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Mutations in the human PARK7 gene that encodes protein DJ-1 lead to familial Parkinsonism due to loss of dopaminergic neurons. However, the molecular function of DJ-1 underpinning its cytoprotective effects are unclear. Recently, DJ-1 has be
Externí odkaz:
https://doaj.org/article/48e7829f9c4e42f09afb11999355b962
Autor:
Darkhan Kanayev, Diana Abilmazhenova, Ilyas Akhmetollayev, Aliya Sekenova, Vyacheslav Ogay, Arman Kulyyassov
Publikováno v:
Life, Vol 13, Iss 1, p 107 (2022)
In vivo biotinylation using wild-type and mutants of biotin ligases is now widely applied for the study of cellular proteomes. The commercial availability of kits for the highly efficient purification of biotinylated proteins and their excellent comp
Externí odkaz:
https://doaj.org/article/d488266acfc44ae18ce778de25cd67ed
Generation of Peptides for Highly Efficient Proximity Utilizing Site-Specific Biotinylation in Cells
Publikováno v:
Life, Vol 12, Iss 2, p 300 (2022)
Protein tags are peptide sequences genetically embedded into a recombinant protein for various purposes, such as affinity purification, Western blotting, and immunofluorescence. Another recent application of peptide tags is in vivo labeling and analy
Externí odkaz:
https://doaj.org/article/a28b39fdbd284c4b8ff5f2d327f99188
Autor:
Arman Kulyyassov
Publikováno v:
Molecules, Vol 26, Iss 23, p 7170 (2021)
Quantitative and qualitative analyses of cell protein composition using liquid chromatography/tandem mass spectrometry are now standard techniques in biological and clinical research. However, the quantitative analysis of protein–protein interactio
Externí odkaz:
https://doaj.org/article/877cd12dfe8a4c5a8f3fd462cfec8274
Autor:
Arman Kulyyassov, Ruslan Kalendar
Publikováno v:
Data, Vol 5, Iss 4, p 111 (2020)
High-throughput sequencing technologies have greatly accelerated the progress of genomics, transcriptomics, and metagenomics. Currently, a large amount of genomic data from various organisms is being generated, the volume of which is increasing every
Externí odkaz:
https://doaj.org/article/e37490991d344ca19759e079b445ee51
Autor:
Arman Kulyyassov, Vasily Ogryzko
Publikováno v:
Biomolecules, Vol 10, Iss 1, p 142 (2020)
Protein−protein interactions of core pluripotency transcription factors play an important role during cell reprogramming. Cell identity is controlled by a trio of transcription factors: Sox2, Oct4, and Nanog. Thus, methods that help to quantify pro
Externí odkaz:
https://doaj.org/article/93d07dcd1ab04ea4b94a10277eb114d7
Publikováno v:
ProteomicsREFERENCES. 21(23-24)
Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) is now the main analytical method for the identification and quantification of peptides and proteins in biological samples. In modern research, identification of biomarkers and thei
Publikováno v:
Central Asian Journal of Global Health, Vol 3, Iss 0 (2015)
Introduction. The human genome consists of roughly 30,000 genes coding for over 500,000 different proteins, of which more than 10,000 proteins can be produced by the cell at any given time (the cellular “proteome”). It has been estimated that ove
Externí odkaz:
https://doaj.org/article/cc9e009e6cfb40f081b34d077105dd5a
Autor:
Arman Kulyyassov, Guldarigash Kuanyshovna Kaukabayeva, Zhuldyz Kydyrbekkyzy Kairova, Zhansaya Batyrbekkyzy Adish, Pavel Viktorovich Tarlykov, Kanatbek Naizabekovich Mukantayev, Kasym Mukanov, Kanat Akhmetovich Tursunov
Publikováno v:
Asia Pacific Journal of Molecular Biology and Biotechnology. :85-95
Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer and very few therapeutic options are currently available for its treatment. Interestingly, G-protein coupled receptor 161 (GPR161) is expressed in TNBC cells and can activate
Publikováno v:
Central Asian Journal of Global Health, Vol 2, Iss 0 (2014)
Introduction: The spatiotemporal order plays an important role in cell functioning and is affected in many pathologies such as cancer and neurodegenerative diseases. One of the ultimate goals of molecular biology is reconstruction of the spatiotempor
Externí odkaz:
https://doaj.org/article/2d4edc5c475549b1bec174d0d5088f04