Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Arlind B. Mara"'
Autor:
Tyler D. Gavitt, Arlind B. Mara, Meagan L. Goodridge, Rosemary Grace Ozyck, Emily Reinhardt, Jeremy M. Miller, Morgan Hunte, Edan R. Tulman, Salvatore Frasca Jr, Lawrence K. Silbart, Steven J. Geary, Steven M. Szczepanek
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract Development of an effective vaccine for Mycoplasma pneumoniae has been hindered by reports of Vaccine Enhanced Disease (VED) in test subjects vaccinated and challenged in studies conducted in the 1960s. The exact mechanism of disease exacerb
Externí odkaz:
https://doaj.org/article/d420621cdec5408f86b7b07590eabe32
Autor:
Arlind B. Mara, Tyler D. Gavitt, Edan R. Tulman, Jeremy M. Miller, Wu He, Emily M. Reinhardt, R. Grace Ozyck, Meagan L. Goodridge, Lawrence K. Silbart, Steven M. Szczepanek, Steven J. Geary
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-14 (2022)
Abstract Bacterial lipoproteins are an often-underappreciated class of microbe-associated molecular patterns with potent immunomodulatory activity. We previously reported that vaccination of BALB/c mice with Mycoplasma pneumoniae (Mp) lipid-associate
Externí odkaz:
https://doaj.org/article/3fe004bc8b8c4a48b7487794ec839411
Autor:
Kavita Rawat, Anita Tewari, Xin Li, Arlind B. Mara, William T. King, Sophie L. Gibbings, Chinaza F. Nnam, Fred W. Kolling, Bart N. Lambrecht, Claudia V. Jakubzick
Publikováno v:
The Journal of experimental medicine, 220(6):e20222129. Rockefeller University Press
Dendritic cells (DCs) and monocytes capture, transport, and present antigen to cognate T cells in the draining lymph nodes (LNs) in a CCR7-dependent manner. Since only migratory DCs express this chemokine receptor, it is unclear how monocytes reach t
Autor:
Xin Li, Arlind B. Mara, Shawn Musial, Kavita Rawat, William T. King, Fred W. Kolling, Nikita Gerebtsov, Claudia V. Jakubzick
Tissue-resident macrophages in the lung comprising alveolar and interstitial macrophages (IMs) display a high degree of heterogeneity. In general, macrophage heterogeneity is thought to arise from various forms of activation that are heavily confound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08ae093426b3b7d18b3edcd6afe95d6d
https://doi.org/10.1101/2023.05.12.540435
https://doi.org/10.1101/2023.05.12.540435
Autor:
Tyler D. Gavitt, Arlind B. Mara, Meagan L. Goodridge, Rosemary Grace Ozyck, Emily Reinhardt, Jeremy M. Miller, Morgan Hunte, Edan R. Tulman, Salvatore Frasca Jr, Lawrence K. Silbart, Steven J. Geary, Steven M. Szczepanek
Publikováno v:
npj Vaccines. 7
Development of an effective vaccine for Mycoplasma pneumoniae has been hindered by reports of Vaccine Enhanced Disease (VED) in test subjects vaccinated and challenged in studies conducted in the 1960s. The exact mechanism of disease exacerbation has
Autor:
Tyler D Gavitt, Jessica L. Rouge, Steven M. Szczepanek, Arlind B Mara, Alyssa K. Hartmann, Shraddha S. Sawant
Publikováno v:
ACS Nano. 15:11192-11201
Allergic asthma is one of the leading chronic lung diseases of both children and adults worldwide, resulting in significant morbidity and mortality in affected individuals. Many patients have severe asthma, which is refractory to treatment, illustrat
Autor:
Tyler D Gavitt, Avi Patel, Roxana Piotrowska, Thanh D. Nguyen, Neha Mishra, Eli J. Curry, Nicholas Farrell, Steven M. Szczepanek, Khanh Thi My Tran, Arlind B Mara, Lindsey Brown, Shawn Kilpatrick
Publikováno v:
Nature Biomedical Engineering. 5:998-1007
Repeated bolus injections are associated with higher costs and poor compliance and can hinder the implementation of global immunization campaigns. Here, we report the development and preclinical testing of patches of transdermal core-shell microneedl
Publikováno v:
npj Vaccines, Vol 5, Iss 1, Pp 1-5 (2020)
Vaccine-enhanced disease (VED) occurs as a result of vaccination followed by infection with virulent Mycoplasma pneumoniae. To date VED has prevented development of an efficacious vaccine against this significant human respiratory pathogen. Herein we
Publikováno v:
NPJ Vaccines
Vaccine-enhanced disease (VED) occurs as a result of vaccination followed by infection with virulent Mycoplasma pneumoniae. To date VED has prevented development of an efficacious vaccine against this significant human respiratory pathogen. Herein we
Autor:
Khanh T M, Tran, Tyler D, Gavitt, Nicholas J, Farrell, Eli J, Curry, Arlind B, Mara, Avi, Patel, Lindsey, Brown, Shawn, Kilpatrick, Roxana, Piotrowska, Neha, Mishra, Steven M, Szczepanek, Thanh D, Nguyen
Publikováno v:
Nature biomedical engineering. 5(9)
Repeated bolus injections are associated with higher costs and poor compliance and can hinder the implementation of global immunization campaigns. Here, we report the development and preclinical testing of patches of transdermal core-shell microneedl