Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Arlette Fellous"'
Autor:
Paul Robel, Etienne-Emile Baulieu, Sebastien David, Virginie Fontaine-Lenoir, Arlette Fellous, Yann Duchossoy, Béatrice Chambraud
Publikováno v:
Proceedings of the National Academy of Sciences. 103:4711-4716
The neurosteroid pregnenolone (PREG) and its chemically synthesized analog 3β-methoxypregnenolone (MePREG) bind to microtubule-associated protein 2 (MAP2) and stimulate the polymerization of microtubules. PREG, MePREG, and progesterone (PROG; the ph
Autor:
David Gancberg, Fatima Cardoso, Marie Christine Bissery, Charles Dumontet, Isabelle Treilleux, Denis Larsimont, Marianne Paesmans, Chantal Bernard-Marty, Arlette Fellous, Angelo Di Leo, Martine Piccart
Publikováno v:
Clinical Breast Cancer. 3:341-345
Docetaxel is currently one of the most active agents for breast cancer. Predictive markers of docetaxel efficacy are clearly needed in order to avoid unnecessary toxicity in nonresponding or resistant patients and to improve the cost-effectiveness ra
Autor:
Arlette Fellous, Marc Fellous
Publikováno v:
Research in microbiology. 165(5)
Autor:
Guy Millot, Philippe Denoulet, Fabien Calvo, Marie-Pierre Podgorniak, Arlette Fellous, Suleeporn Sangrajrang, Kenneth D. Tew, Roger Tatoud
Publikováno v:
International Journal of Cancer. 77:626-631
Estramustine (EM) is an anti-microtubule drug used in the treatment of hormone-refractory advanced prostate cancer. Since microtubules are the targets for EM cytotoxicity, we investigated the effects of EM on the microtubule-associated protein tau to
Publikováno v:
European Journal of Biochemistry. 220:847-853
In higher-plant cells, the different cell-cycle-dependent microtubule arrays are involved in a wide range of activities including chromosome segregation, cell-plate formation and cellulose microfibril distribution and orientation. A wealth of data, o
Autor:
Walter Gilbert, Arlette Fellous, Chris Ottolenghi, Michel Jacquet, Iraj Daizadeh, Albert Ju, Reiner A. Veitia, Sophia Kossida, Georges Renault
Publikováno v:
Scopus-Elsevier
We have recently cloned the gene C14orf1, which is strongly expressed in normal testis and in several cancer cell lines and tumors. This gene maps to 14q24.3 and is interrupted by four introns. Two of them are also represented in the open reading fra
Publikováno v:
Biology of the Cell. 68:21-29
The response of microtubules to treatment with vinca alkaloids was investigated in vivo and in situ in the embryonic nervous system of mice. For this purpose we used rotatory cultures of post-implanted embryos in a serum medium containing the alkaloi
Autor:
Etienne-Emile Baulieu, Arlette Fellous, Hamida Belabes, Béatrice Chambraud, Virginie Fontaine-Lenoir
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 21(11)
The FK506 binding protein FKBP52 belongs to the large family of immunophilins and is known as a steroid receptor-associated protein. Previous data suggest that FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosi
Autor:
Paul Robel, Yann Duchossoy, Sebastien David, Etienne-Emile Baulieu, Arlette Fellous, Virginie Fontaine-Lenoir
Publikováno v:
Journal of molecular neuroscience : MN. 24(1)
MAPREG (microtubule-associated protein/neurosteroidal pregnenolone) is a start-up company that was created in October 2000. Its acronym recalls the basic discovery (Murakami et al., 2000) from which drug(s) will hopefully be developed that are useful
Publikováno v:
Cell and tissue research. 308(2)
Microtubules are cylindrical organelles that play critical roles in cell division. Their subunit protein, tubulin, is a target for various antitumor drugs. Tubulin exists as various forms, known as isotypes. In most normal cells, tubulin occurs only