Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Arlet Minassian"'
Autor:
Arlet Minassian, Junjie Zhang, Shanping He, Jun Zhao, Ebrahim Zandi, Takeshi Saito, Chengyu Liang, Pinghui Feng
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1005060 (2015)
Activation of pattern recognition receptors and proper regulation of downstream signaling are crucial for host innate immune response. Upon infection, the NF-κB and interferon regulatory factors (IRF) are often simultaneously activated to defeat inv
Externí odkaz:
https://doaj.org/article/2e125a57b26f4cbaa98ac0e0658d8c76
NF-κB transcription factors regulate the expression of hundreds of genes primarily involved in immune responses. Signaling events leading to NF-κB activation constitute a major antiviral immune pathway. To replicate and persist within their hosts,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf8300b33373258a4dfa9c3894262d4
https://europepmc.org/articles/PMC4688235/
https://europepmc.org/articles/PMC4688235/
Autor:
Chengyu Liang, Ebrahim Zandi, Xiaojing He, Kevin Brulois, Yuqi Wang, Jae U. Jung, Pinghui Feng, Junjie Zhang, Shanshan Song, Arlet Minassian, Jun Zhao, Jackson Cabo, Xuewu Zhang, Shanping He, Yu Zhou
Publikováno v:
Molecular cell. 58(1)
RIG-I is a pattern recognition receptor that senses viral RNA and is crucial for host innate immune defense. Here, we describe a mechanism of RIG-I activation through amidotransferase-mediated deamidation. We show that viral homologs of phosphoribosy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3602c971c9db3131fbfa77d822ce3720
https://pubmed.ncbi.nlm.nih.gov/25839430
https://pubmed.ncbi.nlm.nih.gov/25839430
Autor:
Chengyu Liang, Joo-Hyung Lee, Hong Gang Wang, Binyun Ma, Rainer Pepperkok, Mitsuo Tagaya, Yoshinori Takahashi, Shanshan He, Irene Ghozalli, Duojiao Ni, Tian Zhang, Pinghui Feng, Baihong Li, Zhen Zhao, Soohwan Oh, Wen-Hwa Lee, Arlet Minassian, Ho Sup Yoon, Nagakumar Bharatham, Vojo Deretic, Sara Dolatshahi Pirooz
Publikováno v:
Nature cell biology
Endoplasmic reticulum (ER)-Golgi membrane transport and autophagy are intersecting trafficking pathways that are tightly regulated and crucial for homeostasis, development and disease. Here, we identify UVRAG, a beclin-1-binding autophagic factor, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1b42ef0dcdc12332dbcf44d1aaca27
https://pubmed.ncbi.nlm.nih.gov/24056303
https://pubmed.ncbi.nlm.nih.gov/24056303