Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Arlene S. Pereira"'
Autor:
Arlene S Pereira, Stephen Taylor
Publikováno v:
Sexually Transmitted Infections. 77:4-11
Because semen is a major vehicle for the sexual transmission of HIV-1, control of viral replication within the sanctuary of the male genital tract should be a goal of antiretroviral therapy. Local immune responses, virus specific factors, and the deg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac0223ae6162e429bad6917641bcfb6
https://doi.org/10.1136/sti.77.1.4
https://doi.org/10.1136/sti.77.1.4
Autor:
Arlene S. Pereira, Richard R Tidwell, Joseph J. Eron, Luigi Troiani, John A. Dunn, Susan A. Fiscus, Myron S. Cohen, James Edwin Hall, Angela D. M. Kashuba
Publikováno v:
The Journal of Infectious Diseases. 180:2039-2043
Human immunodeficiency virus (HIV) can be transmitted in semen from a man to his sexual partners. Antiretroviral drugs are likely to affect the amount of HIV-1 in semen and perhaps transmission of the virus. The concentrations of zidovudine, lamivudi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a2ef899342f035c39ceb9b91a32c0a
https://doi.org/10.1086/315149
https://doi.org/10.1086/315149
Autor:
Mary Beth Wire, Joseph J. Eron, Angela D. M. Kashuba, Arlene S. Pereira, Naumann I. Chaudry, Susan A. Fiscus, Odin J. Naderer
Publikováno v:
Clinical Infectious Diseases. 35:760-762
We compared seminal plasma pharmacokinetic data for the investigational amprenavir prodrug GW433908 with those for amprenavir and an amprenavir-ritonavir combination regimen. All 3 regimens resulted in detectable blood plasma and seminal plasma conce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e534e75cbd5a99df327688fe43388f1d
https://doi.org/10.1086/342389
https://doi.org/10.1086/342389
Autor:
Arlene S. Pereira, Kathryn B Kenney, Richard R. Tidwell, Joseph J. Eron, John A. Dunn, Myron S. Cohen
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 766(2)
A HPLC–MS–MS method to measure amprenavir in human seminal plasma has been developed and validated. The procedure uses stable, isotopically labeled 13C6-amprenavir as an internal standard and 100 μl of sample. The method is accurate (bias less t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f816651c96ae05c63f2d51e6953c93
https://pubmed.ncbi.nlm.nih.gov/11824819
https://pubmed.ncbi.nlm.nih.gov/11824819
Autor:
Richard R. Tidwell, Arlene S. Pereira
Publikováno v:
Journal of chromatography. B, Biomedical sciences and applications. 764(1-2)
Clinicians design antiretroviral therapy to prevent HIV-1 replication and resistance, and researchers study antiretroviral concentrations to understand the pharmacokinetics of these drugs. Because drug efficacy and toxicity varies widely between pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1703f64671b89e1b4718d773aa92aec
https://pubmed.ncbi.nlm.nih.gov/11817036
https://pubmed.ncbi.nlm.nih.gov/11817036
Autor:
Arlene S. Pereira, John G. Gerber, Richard R. Tidwell, Susan A. Fiscus, Joseph J. Eron, Roy M. Gulick, Edward P. Acosta, Robert L. Murphy, Sally Snyder, Laura M. Smeaton
Publikováno v:
The Journal of infectious diseases. 186(2)
The AIDS Clinical Trials Group Study 850 (ACTG 850) evaluated the penetration of zidovudine (ZDV), lamivudine (3TC), and amprenavir (APV), given alone and in combination with the 2 nucleoside analogues, into the male genital tract, because these fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c6a4fb35ab355c4faf5a04d5a2cd06
https://pubmed.ncbi.nlm.nih.gov/12134255
https://pubmed.ncbi.nlm.nih.gov/12134255
Publikováno v:
Antimicrobial agents and chemotherapy. 45(7)
To establish whether a feline model can predict nucleoside analogue behavior in human semen, zidovudine (ZDV) and lamivudine (3TC) pharmacokinetic parameters (PKs) were determined in the blood and seminal plasma of healthy cats. Our results show cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda350a1a8b8c630feb917102b526dc8
https://pubmed.ncbi.nlm.nih.gov/11408248
https://pubmed.ncbi.nlm.nih.gov/11408248
Autor:
Arlene S. Pereira, James Edwin Hall, Kathryn B Kenney, Myron S. Cohen, Richard R. Tidwell, John A. Dunn, Joseph J. Eron
Publikováno v:
Journal of chromatography. B, Biomedical sciences and applications. 742(1)
A HPLC-MS-MS method was developed and validated to measure lamivudine and zidovudine simultaneously in small volumes of human seminal plasma. Sample preparation was simple and rapid, requiring 25 microl of sample, the use of isotopically labeled lami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf44cc3d9aa73b94e721f7399b7d8eb5
https://pubmed.ncbi.nlm.nih.gov/10892596
https://pubmed.ncbi.nlm.nih.gov/10892596