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pro vyhledávání: '"Arlene J. George"'
Autor:
Arlene J. George, Bin Dong, Hannah Lail, Morgan Gomez, Yarely C. Hoffiz, Christopher B. Ware, Ning Fang, Anne Z. Murphy, Erik Hrabovszky, Desiree Wanders, Angela M. Mabb
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105108- (2022)
Externí odkaz:
https://doaj.org/article/ca1e57a0e62e4111a9e9a68f461edfb3
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Protein ubiquitination is a posttranslational modification that plays an integral part in mediating diverse cellular functions. The process of protein ubiquitination requires an enzymatic cascade that consists of a ubiquitin activating enzyme (E1), u
Externí odkaz:
https://doaj.org/article/4d13bdf0d045472a91b3afd12ccf6e0f
Autor:
C. Ware, Ning Fang, Arlene J. George, Yarely C. Hoffiz, Bin Dong, E. Hrabovszky, Angela M. Mabb
SummaryRNF216/TRIAD3 is an E3 ligase that ubiquitinates substrates in the nervous system. Recessive mutations in RNF216/TRIAD3 cause Gordon Holmes syndrome (GHS), where hypogonadotropic hypogonadism is a core phenotype. However, the functions of RNF2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2882c03e085a8b863873bc907748dcec
https://doi.org/10.1101/2021.03.21.436306
https://doi.org/10.1101/2021.03.21.436306
Autor:
Arlene J. George, Yarely C. Hoffiz, Christopher Ware, Bin Dong, Ning Fang, Erik Hrabovszky, Angela M. Mabb
Publikováno v:
SSRN Electronic Journal.
Autor:
Lamiyah F. Mussaji, Arlene J. George, Elara M. Ruszkowski, Alexandra Castillo-Ruiz, Andrew J. Jacobs, Andrew T. Gewirtz, Morgan Mosley, Nancy G. Forger, Benoit Chassaing, Evan F. Fullerton
Publikováno v:
Brain, Behavior, and Immunity. 67:218-229
The mammalian fetus develops in a largely sterile environment, and direct exposure to a complex microbiota does not occur until birth. We took advantage of this to examine the effect of the microbiota on brain development during the first few days of
Autor:
Dawn R. Collins, Jason D. Shepherd, Sheryl S. Moy, Benjamin D. Philpot, Sônia A. L. Corrêa, Zachary D. Allen, Viktoriya D. Nikolova, Michael D. Ehlers, Arlene J. George, Jürgen Müller, Samantha L. Chery, Mark J. Wall, Elissa D. Pastuzyn, Angela M. Mabb
Publikováno v:
Neuron
Summary Neuronal activity regulates the transcription and translation of the immediate-early gene Arc/Arg3.1, a key mediator of synaptic plasticity. Proteasome-dependent degradation of Arc tightly limits its temporal expression, yet the significance