Phase 1 trial of nelfinavir added to standard cisplatin chemotherapy with concurrent pelvic radiation for locally advanced cervical cancer

Autor: Lauren E. Schwartz, J.M. Pearson, Jennifer J. Hu, Lorraine Portelance, Edward A. Jimenez, Margaret Whicker, Nathalie D. McKenzie, Joseph A. Lucci, Gordon B. Mills, Rehman Qureshi, Lilie L. Lin, Fiona Simpkins, Arlene E. Garcia-Soto, Amit Maity, Andrew V. Kossenkov

Publikováno v: Cancer

Background Nelfinavir (NFV), an HIV‐1 protease inhibitor, has been shown to sensitize cancer cells to chemoradiation (CRT). The objectives of this phase 1 trial were to evaluate safety and identify the recommended phase 2 dose of NFV added to concu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449759500804212a2ce14720d311245e
http://europepmc.org/articles/PMC8252376

Incidental power morcellation of malignancy: A retrospective cohort study

Autor: Vanessa Valarezo, Michael M. Aziz, Paul B. Heller, Charbel Salamon, Brian M. Slomovitz, Nana Tchabo, Joseph Ramieri, Craig Dise, Daniel H. Tobias, Arlene E. Garcia-Soto, Kerry Graebe

Publikováno v: Gynecologic Oncology. 136:274-277

Objective Uterine fibroids often require hysterectomy via a laparotomy or utilizing minimally invasive surgical (MIS) approach. Morcellation is a fragmentation of the uterus into smaller pieces. The objective of this study is to determine the inciden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e236c96f8a4d0d90cf7b46ee8b7bb610
https://doi.org/10.1016/j.ygyno.2014.11.018

Secreted heat shock protein gp96-Ig: next-generation vaccines for cancer and infectious diseases

Autor: Natasa Strbo, Arlene E. Garcia-Soto, Taylor H. Schreiber, Eckhard R. Podack

Publikováno v: Immunologic Research. 57:311-325

Over the past decade, our laboratory has developed a secreted heat shock protein (HSP), chaperone gp96, cell-based vaccine that generates effective anti-tumor and anti-infectious immunity in vivo. Gp96-peptide complexes were identified as an extremel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed385c0d2eed49cd176ccbf3662e6e63
https://doi.org/10.1007/s12026-013-8468-x

Does time interval between surgery and intraperitoneal chemotherapy administration in advanced ovarian cancer carry a prognostic impact? An NRG Oncology/Gynecologic Oncology Group study ancillary study

Autor: Angeles Alvarez Secord, Larry J. Copeland, James J. Java, J. Matthew Pearson, Wilberto Nieves Neira, Arlene E. Garcia-Soto, Joan L. Walker, Deborah K. Armstrong, David E. Cohn, Krishnansu S. Tewari, Shashikant Lele

Publikováno v: Garcia-Soto, AE; Java, JJ; Nieves Neira, W; Pearson, JM; Cohn, DE; Lele, SB; et al.(2016). Does time interval between surgery and intraperitoneal chemotherapy administration in advanced ovarian cancer carry a prognostic impact? An NRG Oncology/Gynecologic Oncology Group study ancillary study. Gynecologic Oncology, 143(3), 484-489. doi: 10.1016/j.ygyno.2016.10.003. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/3373n99g

© 2016 Elsevier Inc. Objectives To determine the relationship of the time from surgery to intraperitoneal (IP) chemotherapy (TSIC) initiation with survival of patients with stage III epithelial ovarian cancer (EOC) patients using ancillary data from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b704215f73c4b32b50684813e993c70
https://pubmed.ncbi.nlm.nih.gov/27726923

Is comprehensive surgical staging needed for thorough evaluation of early-stage ovarian carcinoma?

Autor: Thomas Heffernen, Arlene E. Garcia-Soto, David Miller, Shana N. Wingo, Todd Boren

Publikováno v: ResearcherID

Objective Patients with ovarian cancer may have occult metastasis at the time of surgery. Our purpose was to determine the prevalence and sites of occult metastasis in epithelial ovarian cancer grossly confined to the ovary and examine the significan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add76b98b3a78d2f58bcb55b5aac796b
https://pubmed.ncbi.nlm.nih.gov/22381608