Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Arlene D Parsons"'
Autor:
Arya Sobhakumari, Laurie Love-Homan, Elise V M Fletcher, Sean M Martin, Arlene D Parsons, Douglas R Spitz, C Michael Knudson, Andrean L Simons
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48175 (2012)
Increased glutathione (GSH) and thioredoxin (Trx) metabolism are mechanisms that are widely implicated in resistance of cancer cells to chemotherapy. The current study determined if simultaneous inhibition of GSH and Trx metabolism enhanced cell kill
Externí odkaz:
https://doaj.org/article/9c3f6038b8924659b32b069d7c274fdd
Autor:
Erin N. McMullen, Payam Katebi Kashi, Arlene D. Parsons, Katherine L. Dengler, Rhiana D. Saunders
Publikováno v:
Journal of gynecology obstetrics and human reproduction. 50(6)
Background Uterine leiomyoma are implicated in certain adverse pregnancy related outcomes such as postpartum hemorrhage. Large submucosal leiomyoma defined as greater than 5 cm, may have higher complication rates; however, high quality data is limite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f0aed13afeb62a8ddbd3dfe2e9202d
https://pubmed.ncbi.nlm.nih.gov/32325269
https://pubmed.ncbi.nlm.nih.gov/32325269
Autor:
Laurie Love-Homan, C. Michael Knudson, Kevin P. Orcutt, Arlene D. Parsons, Arya Sobhakumari, Andrean L. Simons, Christopher E. Kowalski
Publikováno v:
Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics. 24:55-64
Poor tumor response to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) is a significant challenge for effective treatment of head and neck squamous cell carcinoma (HNSCC). Therefore, strategies that may increase tumor respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cf2c328b56c1c975152d9d3f261dcd
https://doi.org/10.3727/096504016x14586627440192
https://doi.org/10.3727/096504016x14586627440192
Autor:
Prabhat C. Goswami, Yueming Zhu, Andrean L. Simons, Zita A. Sibenaller, Francis J. Miller, Kevin P. Orcutt, Peter M. Scarbrough, Arya Sobhakumari, Werner W. Wilke, Douglas R. Spitz, Amanda L. Kalen, Arlene D. Parsons
Publikováno v:
Cancer Research. 71:3932-3940
Redox regulation of epidermal growth factor receptor (EGFR) signaling helps protect cells against oxidative stress. In this study, we investigated whether the cytotoxicity of an EGFR tyrosine kinase inhibitor, erlotinib (ERL), was mediated by inducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb84e0e19446a7bcce354a8d2c254134
https://doi.org/10.1158/0008-5472.can-10-3425
https://doi.org/10.1158/0008-5472.can-10-3425
Autor:
C. Michael Knudson, Arya Sobhakumari, Elise V.M. Fletcher, Douglas R. Spitz, Andrean L. Simons, Laurie Love-Homan, Sean M. Martin, Arlene D. Parsons
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48175 (2012)
PLoS ONE
PLoS ONE
Increased glutathione (GSH) and thioredoxin (Trx) metabolism are mechanisms that are widely implicated in resistance of cancer cells to chemotherapy. The current study determined if simultaneous inhibition of GSH and Trx metabolism enhanced cell kill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39effb44b5133b2005839025cdba37e9
http://europepmc.org/articles/PMC3485193?pdf=render
http://europepmc.org/articles/PMC3485193?pdf=render
Autor:
Arlene D. Parsons, Kevin P. Orcutt, Andrean L. Simons, Douglas R. Spitz, Melissa A. Fath, Katherine A. Foster
Publikováno v:
Journal of Oncology, Vol 2009 (2009)
Journal of Oncology
Journal of Oncology
The hypothesis that the Akt inhibitor, perifosine (PER), combined with inhibitors of glutathione (GSH) and thioredoxin (Trx) metabolism will induce cytotoxicity via metabolic oxidative stress in human head and neck cancer (HNSCC) cells was tested. PE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ea88190c92c6fa0b90c157b2d02647
https://doaj.org/article/70ef701ec6324f96a25d4163c03ed0f5
https://doaj.org/article/70ef701ec6324f96a25d4163c03ed0f5
Autor:
Peter M. Scarbrough, Francis J. Miller, Douglas R. Spitz, Yueming Zhu, Werner W. Wilke, Arya Sobhakumari, Kevin P. Orcutt, Arlene D. Parsons, Zita A. Sibenaller, Prabhat C. Goswami, Andrean L. Simons, Amanda L. Kalen
Publikováno v:
Free Radical Biology and Medicine. 49:S102-S103
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96cce3196bc37c0c064892a3adbd4f2a
https://doi.org/10.1016/j.freeradbiomed.2010.10.270
https://doi.org/10.1016/j.freeradbiomed.2010.10.270
Autor:
Arlene D. Parsons, Arya Sobhakumari, Michael L. McCormick, Andrean L. Simons, Douglas R. Spitz
Publikováno v:
Free Radical Biology and Medicine. 49:S71
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::316b558f69a14d5871dc00f6f4236627
https://doi.org/10.1016/j.freeradbiomed.2010.10.176
https://doi.org/10.1016/j.freeradbiomed.2010.10.176