Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Arlene A. Hirano"'
Vesicular Release of GABA by Mammalian Horizontal Cells Mediates Inhibitory Output to Photoreceptors
Autor:
Arlene A. Hirano, Helen E. Vuong, Helen L. Kornmann, Cataldo Schietroma, Salvatore L. Stella, Steven Barnes, Nicholas C. Brecha
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Feedback inhibition by horizontal cells regulates rod and cone photoreceptor calcium channels that control their release of the neurotransmitter glutamate. This inhibition contributes to synaptic gain control and the formation of the center-surround
Externí odkaz:
https://doaj.org/article/a0c33ade00e54b5ebfac423249325d12
Publikováno v:
The Journal of Neuroscience. 43:2291-2304
Increasing spike rates drive greater neuronal energy demand. In turn, mitochondrial ATP production leads to the generation of reactive oxygen species (ROS) that can modulate ion channel gating. Does ROS production autoregulate the excitability of a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::affbea33be9c3429beccf9f4e5fd8694
https://doi.org/10.1523/jneurosci.1723-22.2023
https://doi.org/10.1523/jneurosci.1723-22.2023
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
How neurons in the eye feed signals back to photoreceptors to optimize sensitivity to patterns of light appears to be mediated by one or more unconventional mechanisms. Via these mechanisms, horizontal cells control photoreceptor synaptic gain and en
Externí odkaz:
https://doaj.org/article/5f08890d589444b9a45db5e5ffc07915
Autor:
Courtney A Burger, Jonathan Alevy, Anna K Casasent, Danye Jiang, Nicholas E Albrecht, Justine H Liang, Arlene A Hirano, Nicholas C Brecha, Melanie A Samuel
Publikováno v:
eLife, Vol 9 (2020)
Structural changes in pre and postsynaptic neurons that accompany synapse formation often temporally and spatially overlap. Thus, it has been difficult to resolve which processes drive patterned connectivity. To overcome this, we use the laminated ou
Externí odkaz:
https://doaj.org/article/28945f0d1256418a9198f66526f7224a
Autor:
James C R Grove, Arlene A Hirano, Janira de Los Santos, Cyrus F McHugh, Shashvat Purohit, Greg D Field, Nicholas C Brecha, Steven Barnes
Publikováno v:
PLoS Biology, Vol 17, Iss 4, p e3000200 (2019)
The stream of visual information sent from photoreceptors to second-order bipolar cells is intercepted by laterally interacting horizontal cells that generate feedback to optimize and improve the efficiency of signal transmission. The mechanisms unde
Externí odkaz:
https://doaj.org/article/c9cd97c2e562426ba6a192bef22ae41e
Autor:
Anna K. Casasent, Nicholas E. Albrecht, Melanie A. Samuel, Danye Jiang, Jonathan Alevy, Arlene A. Hirano, Courtney A. Burger, Justine H Liang, Nicholas C. Brecha
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Structural changes in pre and postsynaptic neurons that accompany synapse formation often temporally and spatially overlap. Thus, it has been difficult to resolve which processes drive patterned connectivity. To overcome this, we use the laminated ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf806e96b08722ef584f082025d36bce
https://doi.org/10.7554/elife.56931
https://doi.org/10.7554/elife.56931
Autor:
Vadim Y. Arshavsky, Arlene A. Hirano, Stephanie J. Heflin, Nicholas C. Brecha, Amanda M. Travis
Publikováno v:
The Journal of Neuroscience. 38:723-732
The vertebrate retina has the remarkable ability to support visual function under conditions of limited illumination, including the processing of signals evoked by single photons. Dim-light vision is regulated by several adaptive mechanisms. The mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e04f0849924fcf19db025fe8d8a79557
https://doi.org/10.1523/jneurosci.1994-17.2017
https://doi.org/10.1523/jneurosci.1994-17.2017
Publikováno v:
The Journal of Physiology. 595:4449-4465
KEY POINTS Large conductance, Ca2+ -activated K+ (BKCa ) channels play important roles in mammalian retinal neurons, including photoreceptors, bipolar cells, amacrine cells and ganglion cells, but they have not been identified in horizontal cells. BK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3b20cfa9cb66f65214e3368ca07b8f1
https://doi.org/10.1113/jp274132
https://doi.org/10.1113/jp274132
Autor:
Steven Barnes, Greg D. Field, Cyrus F McHugh, Shashvat Purohit, James C. R. Grove, Nicholas C. Brecha, Arlene A. Hirano, Janira de los Santos
Publikováno v:
PLoS biology, vol 17, iss 4
PLoS Biology, Vol 17, Iss 4, p e3000200 (2019)
PLoS Biology, Vol 17, Iss 4, p e3000200 (2019)
The stream of visual information sent from photoreceptors to second-order bipolar cells is intercepted by laterally interacting horizontal cells that generate feedback to optimize and improve the efficiency of signal transmission. The mechanisms unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5d6dd5e168ad9609d0b4a030c04bf5
https://escholarship.org/uc/item/90h1c95f
https://escholarship.org/uc/item/90h1c95f
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1753
Genetic manipulation of horizontal cells using a Connexin57-iCre mouse (Cx57-iCre) line combined with calcium imaging is proving to be a valuable method to study horizontal cell feedback inhibition onto photoreceptor terminals. While it is accepted t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96bd7338987cf7e5df1d8950dd742751
https://pubmed.ncbi.nlm.nih.gov/29564789
https://pubmed.ncbi.nlm.nih.gov/29564789