Gram Scalable Method to Synthesize Biscarbodiimides and Asymmetric Monocarbodiimides: A Platform to Access an Array of Phosphaguanidines, Amidines, and Guanidines

Autor: Andrew M. Camelio, Arkady Krasovskiy, Bailey Brad C, Anna V Davis

Publikováno v: The Journal of Organic Chemistry. 87:2022-2044

A mild, broadly functional group tolerant methodology has been developed to access a variety of mono- and bis-carbodiimides in good yield and high purity on multigram scale. Direct addition into these versatile motifs facilitated the rapid synthesis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397e38c1e1e76871162d0be6a49effbd
https://doi.org/10.1021/acs.joc.1c01281

Catalysis in the Service of Green Chemistry: Nobel Prize-Winning Palladium-Catalysed Cross-Couplings, Run in Water at Room Temperature

Autor: Subir Ghorai, Arkady Krasovskiy, Benjamin R. Taft, Bruce H. Lipshutz, Alexander R. Abela, Christophe Duplais

Publikováno v: Platinum Metals Review. 56:62-74

Palladium-catalysed cross-couplings, in particular Heck, Suzuki-Miyaura and Negishi reactions developed over three decades ago, are routinely carried out in organic solvents. However, alternative media are currently of considerable interest given an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5a00ed0bb46f946b11a11c329159551
https://doi.org/10.1595/147106712x629761

'Greening Up' Cross-Coupling Chemistry

Autor: Arkady Krasovskiy, Bruce H. Lipshutz, Alexander R. Abela, Takashi Nishikata, Žarko V. Bošković, Christophe Duplais

Publikováno v: Lipshutz, Bruce H.; Abela, Alexander R.; Bošković, Žarko V.; Nishikata, Takashi; Duplais, Christophe; & Krasovskiy, Arkady. (2010). “Greening Up” Cross-Coupling Chemistry. Topics in Catalysis, 53(15), pp 985-990. doi: 10.1007/s11244-010-9537-1. Retrieved from: http://www.escholarship.org/uc/item/0ts1v52w

New methodologies that enable palladium catalyzed cross-coupling reactions to be performed under environmentally benign conditions (in water and/or at room temperature) have been developed. Described approaches involve in situ activation of carbon–

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d668e2037cc9d012a9497a447e752fe6
https://doi.org/10.1007/s11244-010-9537-1

Stereoselective Preparation of Cyclopropylmagnesium Reagents via a Br-Mg Exchange Using i-PrMgCl×LiCl in the Presence of Dioxane

Autor: Paul Knochel, Arkady Krasovskiy, Christian B. Rauhut, Christian Cervino

Publikováno v: Synlett. 2009:67-70

The reaction of various cyclopropyl bromides with I-PrMgCl˙LiCl in THF-dioxaneprovides the corresponding magnesiated cyclopropane reagents withcomplete retention of configuration.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8fee5ae207f973feba4ae5ac14d3584b
https://doi.org/10.1055/s-0028-1087487

An Expedient Strategy for the Synthesis of Tryptamines and Other Heterocycles

Autor: K. C. Nicolaou, Arkady Krasovskiy, Vincent É. Trépanier, David Y.-K. Chen

Publikováno v: Angewandte Chemie. 120:4285-4288

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ce4d3e2d335180261f2172e5ce866d7
https://doi.org/10.1002/ange.200800404