Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Arkady I Gusev"'
Autor:
Claudia Hon, Ma’en Obeidat, Jason M. Laramie, Philippe Marc, Pablo Serrano-Fernandez, Paul M. Ridker, Margaret L Healey, Michael T. Beste, Arkady I Gusev, Aviv Madar, Huilei Xu, Nicole Hartmann, Denise Yates, Scott Kennedy, Sergio Kaiser, Eric C. Svensson
Publikováno v:
Circulation: Genomic and Precision Medicine. 14
No formal abstract in format we plan to submit to journal (a short report). Informally, the work presented here adds to a body of evidence that shows how polygenic risk scores (PRS) for coronary artery disease (CAD) can be used to inform on patient's
Autor:
Xiaojing Yu, Arkady I Gusev
Publikováno v:
Bioanalysis. 11:1309-1313
Publikováno v:
Bioanalysis. 12(16)
Outsourcing is a common strategy across the pharmaceutical industry and clinical research. CROs offer many choices for selecting outsourcing partners for bioanalytical and biomarker support. We aimed this paper to provide critical insights into CRO b
Publikováno v:
Bioanalysis. 12(13)
Aim: Evaluation of a novel microsampling device for its use in clinical sample collection and biomarker analysis. Methodology: Matching samples were collected from 16 healthy donors (ten females, six males; age 42 ± 20) via K2EDTA touch activated ph
Autor:
Tianke Wang, Arkady I Gusev
Publikováno v:
Bioanalysis. 9:501-504
Productivity and efficiency of pharmaceutical R&D has been a subject of multiple discussions and publications. Outsourcing is one of the common approaches pharmaceutical industry employs to address R&D challenges. Outsourcing in the pharma R&D was in
Autor:
Honggang Bi, Rachael Leverence, Michael J. Avery, Olga Kavetskaia, Cornelis E.C.A. Hop, Arkady I. Gusev
Publikováno v:
Biomedical Chromatography. 21:1143-1150
This paper presents a study of the signal suppression and enhancement effects in assays based on HPLC-ESI-MS/MS detection. The major focus was to investigate the effect of signal suppression/enhancement of typical co-administered (concomitant) medica
Publikováno v:
Analytical Chemistry. 78:1331-1336
A novel approach for on-line introduction of internal standard (IS) for quantitative analysis using LC-MS/MS has been developed. In this approach, analyte and IS are introduced into the sample injection loop in different steps. Analyte is introduced
Autor:
Honggang Bi, Olga Kavetskaia, David Waddell, Arkady I. Gusev, Karthik Srinivasan, Yazen Alnouti
Publikováno v:
Journal of Chromatography A. 1080:99-106
A technique using a fully automated on-line solid phase extraction (SPE) system (Symbiosis, Spark Holland) combined with liquid chromatography (LC)–mass spectrometry (MS/MS) has been investigated for fast bioanalytical method development, method va
Autor:
Arkady I Gusev, Keith A. Wharton, Pierre Moulin, Benjamin H. Lee, Dale Mongeon, Xiaoyu Jiang, Bin Ye, Rainer Hillenbrand
Publikováno v:
Methods in Pharmacology and Toxicology ISBN: 9781493926800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d477c0ba4d197029c627faf5a1b3fd8c
https://doi.org/10.1007/7653_2014_28
https://doi.org/10.1007/7653_2014_28
Publikováno v:
Analytical Chemistry. 73:6014-6023
The effect of liquid chromatographic separation on matrix-related signal suppression in electrospray ionization mass spectrometry (LC-ESI-MS) was investigated. A method incorporating on-line two-dimensional liquid chromatography mass spectrometry (LC