Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Arkadiusz Rybicki"'
Autor:
Pauline Mencke, Zoé Hanss, Javier Jarazo, François Massart, Arkadiusz Rybicki, Elizabet Petkovski, Enrico Glaab, Ibrahim Boussaad, Vincenzo Bonifati, Jens Christian Schwamborn, Wim Mandemakers, Rejko Krüger
Publikováno v:
Stem Cell Research, Vol 62, Iss , Pp 102815- (2022)
We describe the generation of an isogenic control cell line DJ-1-delP GC13 from an induced pluripotent stem cell (iPSC) line DJ-1-delP LCSBi008-A that was derived from fibroblasts obtained from a Parkinson’s disease (PD) patient. Using CRISPR/Cas9
Externí odkaz:
https://doaj.org/article/98b9fec390b8422c9118d59c5484a789
Autor:
Marti Cabanes-Creus, Adrian Westhaus, Renina Gale Navarro, Grober Baltazar, Erhua Zhu, Anais K. Amaya, Sophia H.Y. Liao, Suzanne Scott, Erwan Sallard, Kimberley L. Dilworth, Arkadiusz Rybicki, Matthieu Drouyer, Claus V. Hallwirth, Antonette Bennett, Giorgia Santilli, Adrian J. Thrasher, Mavis Agbandje-McKenna, Ian E. Alexander, Leszek Lisowski
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 1139-1154 (2020)
Use of the prototypical adeno-associated virus type 2 (AAV2) capsid delivered unexpectedly modest efficacy in an early liver-targeted gene therapy trial for hemophilia B. This result is consistent with subsequent data generated in chimeric mouse-huma
Externí odkaz:
https://doaj.org/article/192ac1b2202f420f9e1d2c4d0646e77d
Autor:
Marti Cabanes-Creus, Samantha L. Ginn, Anais K. Amaya, Sophia H.Y. Liao, Adrian Westhaus, Claus V. Hallwirth, Patrick Wilmott, Jason Ward, Kimberley L. Dilworth, Giorgia Santilli, Arkadiusz Rybicki, Hiroyuki Nakai, Adrian J. Thrasher, Adrian C. Filip, Ian E. Alexander, Leszek Lisowski
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 12, Iss , Pp 71-84 (2019)
Adeno-associated virus (AAV) vectors have become one of the most widely used gene transfer tools in human gene therapy. Considerable effort is currently being focused on AAV capsid engineering strategies with the aim of developing novel variants with
Externí odkaz:
https://doaj.org/article/e371436ebdb346fc97df68b085539c0c
Autor:
Eveline Santos da Silva, Martin Mulinge, Morgane Lemaire, Cécile Masquelier, Cyprien Beraud, Arkadiusz Rybicki, Jean-Yves Servais, Gilles Iserentant, Jean-Claude Schmit, Carole Seguin-Devaux, Danielle Perez Bercoff
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161596 (2016)
The cytoplasmic tail (gp41CT) of the HIV-1 envelope (Env) mediates Env incorporation into virions and regulates Env intracellular trafficking. Little is known about the functional impact of variability in this domain. To address this issue, we compar
Externí odkaz:
https://doaj.org/article/d84de37696374dfc8038e72307f33f20
Autor:
Grober Baltazar, Anais K. Amaya, Antonette Bennett, Erhua Zhu, Leszek Lisowski, Adrian J. Thrasher, Sophia H.Y. Liao, Renina Gale Navarro, Marti Cabanes-Creus, Mavis Agbandje-McKenna, Ian E. Alexander, Giorgia Santilli, Arkadiusz Rybicki, Suzanne Scott, Erwan Sallard, Matthieu Drouyer, Adrian Westhaus, Claus V. Hallwirth, Kimberley L. Dilworth
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 1139-1154 (2020)
Use of the prototypical adeno-associated virus type 2 (AAV2) capsid delivered unexpectedly modest efficacy in an early liver-targeted gene therapy trial for hemophilia B. This result is consistent with subsequent data generated in chimeric mouse-huma
Autor:
Kenneth Hsu, Arkadiusz Rybicki, Magdalena Kwiatek, Anai Gonzalez-Cordero, Razvan F Albu, Marti Cabanes-Creus, Erhua Zhu, Predrag Kalajdzic, Matthieu Drouyer, Maddison Knight, Adrian J. Thrasher, Grober Baltazar, Ian E. Alexander, Boaz H. Ng, Adrian Westhaus, Renina Gale Navarro, Leszek Lisowski, Giorgia Santilli, Belinda Kramer, Wendy A. Gold
Publikováno v:
Human Gene Therapy. 31:575-589
Adeno-associated virus (AAV) vectors are quickly becoming the vectors of choice for therapeutic gene delivery. To date, hundreds of natural isolates and bioengineered variants have been reported. While factors such as high production titer and low im
Autor:
Kimberley L. Dilworth, Adrian J. Thrasher, Arkadiusz Rybicki, Claus V. Hallwirth, Anais K. Amaya, Adrian C. Filip, Leszek Lisowski, Jason Ward, Sophia H.Y. Liao, Ian E. Alexander, Samantha L. Ginn, Patrick Wilmott, Hiroyuki Nakai, Giorgia Santilli, Marti Cabanes-Creus, Adrian Westhaus
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 12, Iss, Pp 71-84 (2019)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Adeno-associated virus (AAV) vectors have become one of the most widely used gene transfer tools in human gene therapy. Considerable effort is currently being focused on AAV capsid engineering strategies with the aim of developing novel variants with
Autor:
Martin Mulinge, Morgane Lemaire, Jean-Yves Servais, Arkadiusz Rybicki, Daniel Struck, Eveline Santos da Silva, Chris Verhofstede, Yolanda Lie, Carole Seguin-Devaux, Jean-Claude Schmit, Danielle Perez Bercoff
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e60566 (2013)
BackgroundHuman Immunodeficiency virus type-1 (HIV) entry into target cells involves binding of the viral envelope (Env) to CD4 and a coreceptor, mainly CCR5 or CXCR4. The only currently licensed HIV entry inhibitor, maraviroc, targets CCR5, and the
Externí odkaz:
https://doaj.org/article/fa11ab77848e4cfbb4d04d1cf5e57b17
Autor:
Martin Mulinge, Morgane Lemaire, Jean-Yves Servais, Arkadiusz Rybicki, Daniel Struck, Eveline Santos da Silva, Chris Verhofstede, Yolanda Lie, Carole Seguin-Devaux, Jean-Claude Schmit, Danielle Perez Bercoff
Publikováno v:
PLoS ONE, Vol 8, Iss 7 (2013)
Externí odkaz:
https://doaj.org/article/a3b6bc35b6b746f984b0b2023910f4b3
Autor:
Adrian, Westhaus, Marti, Cabanes-Creus, Arkadiusz, Rybicki, Grober, Baltazar, Renina Gale, Navarro, Erhua, Zhu, Matthieu, Drouyer, Maddison, Knight, Razvan F, Albu, Boaz H, Ng, Predrag, Kalajdzic, Magdalena, Kwiatek, Kenneth, Hsu, Giorgia, Santilli, Wendy, Gold, Belinda, Kramer, Anai, Gonzalez-Cordero, Adrian J, Thrasher, Ian E, Alexander, Leszek, Lisowski
Publikováno v:
Human Gene Therapy
Adeno-associated virus (AAV) vectors are quickly becoming the vectors of choice for therapeutic gene delivery. To date, hundreds of natural isolates and bioengineered variants have been reported. While factors such as high production titer and low im