Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Arkadiusz Czerwonka"'
Autor:
Arkadiusz Czerwonka, Joanna Kałafut, Shaoxia Wang, Alinda Anameric, Alicja Przybyszewska-Podstawka, Mervi Toriseva, Matthias Nees
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116822- (2024)
Aberration of Notch signaling is one of the key events involved in the development and progression of head and neck squamous cell carcinoma (HNSCC). The Notch pathway controls the tissue-specific differentiation of normal squamous epithelial cells an
Externí odkaz:
https://doaj.org/article/dc173e8c518f48df9aacca0bb86ccdd1
Autor:
Arkadiusz Czerwonka, Joanna Kałafut, Shaoxia Wang, Alinda Anameric, Alicja Przybyszewska-Podstawka, Jesse Mattsson, Mahtab Karbasian, Doriane Le Manach, Mervi Toriseva, Matthias Nees
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Notch signalling is one of the key molecular pathways involved in cell-to-cell signal transduction. Although the mechanisms of action of the NOTCH receptors are already relatively well known, their biological implications remain unclear, esp
Externí odkaz:
https://doaj.org/article/9c02c842501f4c619df5ba8b69591f58
Autor:
Joanna Kałafut, Jakub Czapiński, Alicja Przybyszewska-Podstawka, Arkadiusz Czerwonka, Adrian Odrzywolski, Cecilia Sahlgren, Adolfo Rivero-Müller
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract The Notch signaling pathway is a crucial regulator of cell differentiation as well as tissue organization, whose deregulation is linked to the pathogenesis of different diseases. NOTCH1 plays a key role in breast cancer progression by increa
Externí odkaz:
https://doaj.org/article/1ae1335d10fe49398ddb79f9c774c978
Autor:
Joanna Kałafut, Arkadiusz Czerwonka, Karolina Czapla, Alicja Przybyszewska-Podstawka, Justyna Magdalena Hermanowicz, Adolfo Rivero-Müller, Lidia Borkiewicz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12579 (2023)
Notch1 signalling plays a multifaceted role in tissue development and homeostasis. Currently, due to the pivotal role of Notch1 signalling, the relationship between NOTCH1 expression and the development of health disorders is being intensively studie
Externí odkaz:
https://doaj.org/article/8d2b67e2059b46c4bae2eede396ef578
Autor:
Karolina Okła, Alicja Rajtak, Arkadiusz Czerwonka, Marcin Bobiński, Anna Wawruszak, Rafał Tarkowski, Wiesława Bednarek, Justyna Szumiło, Jan Kotarski
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Background Previous studies have shown clinical relevance of programmed death-ligand 1 (PD-L1) and soluble PD-L1 (sPD-L1) in human cancers. However, still contradictory results exist. Our aim was evaluation of PD-L1-expressing monocytic myel
Externí odkaz:
https://doaj.org/article/09e0ea1e3ac0445e9da4046a5d38a45d
Publikováno v:
Cells, Vol 12, Iss 5, p 701 (2023)
Background: Ovarian cancer (OC) is the most lethal malignancy of the female reproductive tract. Consequently, a better understanding of the malignant features in OC is pertinent. Mortalin (mtHsp70/GRP75/PBP74/HSPA9/HSPA9B) promotes cancer development
Externí odkaz:
https://doaj.org/article/05abdb9061f7406d9e58685f438cee64
Autor:
Sylwia Nakonieczna, Aneta Grabarska, Kinga Gawel, Paula Wróblewska-Łuczka, Arkadiusz Czerwonka, Andrzej Stepulak, Wirginia Kukula-Koch
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10330 (2022)
Gastric cancer (GC) has high incidence rates and constitutes a common cause of cancer mortality. Despite advances in treatment, GC remains a challenge in cancer therapy which is why novel treatment strategies are needed. The interest in natural compo
Externí odkaz:
https://doaj.org/article/96c6894e9ecd4dc6b8f27f1cbe7c5bb4
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6458 (2022)
Breast cancer (BC) is a heterogeneous disease with different intrinsic subtypes. The most aggressive subtype of BC–triple-negative breast cancer (TNBC) is characterized by high heterogeneity and metastasis rate, poor prognosis and lack of therapeut
Externí odkaz:
https://doaj.org/article/d7c6cbf6babf4f1ab8a66abfc4496c0e
Publikováno v:
Cells, Vol 11, Iss 7, p 1211 (2022)
Breast carcinoma (BC) is the most commonly diagnosed type of cancer in women in the world. Although the advances in the treatment of BC patients are significant, numerous side effects, severe toxicity towards normal cells as well as the multidrug res
Externí odkaz:
https://doaj.org/article/f5ffa4c68d1e4df0898ab48924500d34
Autor:
Arkadiusz Czerwonka, Marta J. Fiołka, Katarzyna Jędrzejewska, Elżbieta Jankowska, Adrian Zając, Wojciech Rzeski
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 126, Iss , Pp 110035- (2020)
Earthworm coelomic fluid (CF) is known as a rich source of various bioactive compounds with promising anticancer features. However, it has been demonstrated that CF affects functionality of both, cancer and normal cells. This non-selective activity c
Externí odkaz:
https://doaj.org/article/6d9de99b449c497fb7c2c89d927679ca