Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Arkadius Pichota"'
2
Preparation and Characterization of New C2- and C1-Symmetric Nitrogen, Oxygen, Phosphorous, and Sulfur Derivatives and Analogs of TADDOL. Part I
Autor: Albert K. Beck, Dieter Seebach, Arkadius Pichota, Volker Gramlich
Publikováno v: Helvetica Chimica Acta. 95:1239-1272
The chloro alcohols 4–6 derived from TADDOLs (=α,α,α′,α′-tetraaryl-1,3-dioxolan-4,5-dimethanols) are used to prepare corresponding sulfanyl alcohols, ethers, and amines (Scheme 1 and Table 1). The dithiol analog of TADDOL and derivatives th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a044380260494b5b2e924bf0ae4892f8
https://doi.org/10.1002/hlca.201200146
Zobrazit plný text záznamu
3
An adenosine nucleoside inhibitor of dengue virus
Autor: Wai Ling Chan, Bo Zhang, Thomas H. Keller, Wouter Schul, Min Qing, Pei Yong Shi, Andy Yip, Kristen A. Bernard, Gang Zou, Hao Ying Xu, Suresh B. Lakshminarayana, Gang Wang, Anne Goh, Wei Liu, Min Dong, Boping Liu, Hui Pen Tan, Handan He, Qing Yin Wang, Margaret Weaver, Feng Gu, Yen Liang Chen, Zheng Yin, Pornwaratt Niyomrattanakit, Chuan Young Ng, Arkadius Pichota, Christine E. Garrett, Véronique Dartois, Joanne Y.H. Lim, Ravinder Reddy Kondreddi, Jeyaraj Duraiswamy, Kai Lin, Chin Chin Lim, Karen Beltz
Publikováno v: Proceedings of the National Academy of Sciences. 106:20435-20439
Dengue virus (DENV), a mosquito-borne flavivirus, is a major public health threat. The virus poses risk to 2.5 billion people worldwide and causes 50 to 100 million human infections each year. Neither a vaccine nor an antiviral therapy is currently a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a316c5d40ed9639ddcd32990e5f5a43e
https://doi.org/10.1073/pnas.0907010106
Zobrazit plný text záznamu
4
A practical view of ‘druggability’
Autor: Thomas H. Keller, Arkadius Pichota, Zheng Yin
Publikováno v: Current Opinion in Chemical Biology. 10:357-361
The introduction of Lipinski's 'Rule of Five' has initiated a profound shift in the thinking paradigm of medicinal chemists. Understanding the difference between biologically active small molecules and drugs became a priority in the drug discovery pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123c0a8f60972e3c108ac23aff717eab
https://doi.org/10.1016/j.cbpa.2006.06.014
Zobrazit plný text záznamu
5
X-Ray, Molecular Diffusion, and NOESY NMR Studies of Chiral, Tetranuclear CuI Catalysts Based on Monodentate Thiol Analogues of TADDOL
Autor: Arkadius Pichota, Michael Wörle, Dieter Seebach, Massimiliano Valentini, Paul S. Pregosin
Publikováno v: Angewandte Chemie International Edition. 39:153-156
The new, stable, chiral thiol-TADDOL Cu(I) catalysts 1 (X=OH, OMe, NMe(2)) reveal an unexpected monodentate complexation mode, both in solution and in the solid state. For the first time, the aggregation state of organocopper complexes has been deter
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::972bc1c2dbe4d5187fbba285e7a1f558
https://doi.org/10.1002/(sici)1521-3773(20000103)39:1<153::aid-anie153>3.0.co
Zobrazit plný text záznamu
6
Röntgenstrukturanalyse, Diffusionsmessungen und NOESY-NMR-Untersuchungen chiraler, vierkerniger CuI-Katalysatoren aus einzähnigen Thiol-Derivaten von TADDOL
Autor: Dieter Seebach, Arkadius Pichota, Paul S. Pregosin, Michael Wörle, Massimiliano Valentini
Publikováno v: Angewandte Chemie. 112:157-160
Die stabilen chiralen CuI-Katalysatoren1 (X=OH, OMe, NMe2) enthalten sowohl in Losung als auch im Festkorper die Thiol-TADDOL-Derivate unerwartet einzahnig koordiniert. Zum ersten Mal wurde die Aggregation von Organokupferkomplexen durch NMR-Diffusio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d105194d26ba7e53c1b964b2674c3440
https://doi.org/10.1002/(sici)1521-3757(20000103)112:1<157::aid-ange157>3.0.co
Zobrazit plný text záznamu
7
Preparation of TADDOL Derivatives for New Applications
Autor: and Jaana Karjalainen, Anthony B. Pinkerton, Albert K. Beck, Dieter Seebach, Volker Gramlich, Thomas Litz, Arkadius Pichota
Publikováno v: Scopus-Elsevier
Substitution of one or both TADDOL OH groups by other functional groups X, Y is key to new applications of this cheap chiral auxiliary. The Appel reaction and treatment with SOCl2 provide the mono- and dichlorides, respectively. The chlorides are, in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aaf57f115214a665c7ae3bdcd3bb950
https://doi.org/10.1021/ol990060d
Zobrazit plný text záznamu
8
Enantioselective 1,4-Addition of AliphaticGrignard Reagents to Enones Catalyzed by Readily Available Copper(I) thiolates derived from TADDOL. Preliminary communication
Autor: Dieter Seebach, Laurent Audergon, Georg Jaeschke, Arkadius Pichota
Publikováno v: Helvetica Chimica Acta. 80:2515-2519
Two simple thiols derived from the parent TADDOL, α,α,α′,α′ tetraphenyl-2,2-dimethyl-1,3-clioxolan-4,5-dimethanol, are used to prepare Cu1 complexes C and D to catalyze (0.05 equiv.) 1,4-additions of Grignard reagents RMgCl to cyclic enones w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9cc09484c9a492c48b760923529f3088
https://doi.org/10.1002/hlca.19970800819
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje