Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Arkadij M. Elizarov"'
Autor:
Joseph C. Walsh, A. Katrin Szardenings, Min-Ying Su, Shadfar Bahri, Hartmuth C. Kolb, William R. Shankle, Arkadij M. Elizarov, David Chien, Alan J. Lerner, Chunfang Xia, Fanrong Mu
Publikováno v:
Chien, DT; Szardenings, AK; Bahri, S; Walsh, JC; Mu, F; Xia, C; et al.(2014). Early clinical PET imaging results with the novel PHF-tau radioligand [F18]-T808. Journal of Alzheimer's Disease, 38(1), 171-184. doi: 10.3233/JAD-130098. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7q6232fs
Journal of Alzheimer's disease : JAD, vol 38, iss 1
Journal of Alzheimer's disease : JAD, vol 38, iss 1
Aggregates of hyperphosphorylated tau (PHF-tau), such as neurofibrillary tangles, are linked to the degree of cognitive impairment in Alzheimer's disease. We have recently reported early clinical results of a novel PHF-tau targeting PET imaging agent
Autor:
Reza Miraghaie, Jiang Huang, Antoine Daridon, Hartmuth C. Kolb, Arkadij M. Elizarov, James R. Heath, Carl D. Meinhart, R. Michael van Dam
Publikováno v:
Biomedical microdevices, vol 13, iss 1
Biomedical Microdevices
Biomedical Microdevices
We present numerical modeling and experimental studies of flow optimization inside a batch microfluidic micro-reactor used for synthesis of human-scale doses of Positron Emission Tomography (PET) tracers. Novel techniques are used for mixing within,
Batch-mode microfluidic radiosynthesis of N-succinimidyl-4-[18F]fluorobenzoate for protein labelling
Autor:
Hartmuth C. Kolb, Ed Ball, Véronique Gouverneur, Reza Miraghaie, Romain Bejot, Arkadij M. Elizarov, Jianzhong Zhang
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 54:117-122
The batch microfluidic technology is a promising system for sequential chemical steps combining the advantages of micro-scale reactions, while addressing some shortcomings of flow-through systems. We report herein the convenient three-step, one-pot s
Autor:
Vincenzo Balzani, Filippo Marchioni, J. Fraser Stoddart, Martin Belohradsky, Margherita Venturi, Hsian-Rong Tseng, Alberto Credi, Arkadij M. Elizarov
Publikováno v:
Journal of the American Chemical Society. 126:568-573
We have prepared and investigated two dendrimers based on a 1,3,5-trisubstituted benzenoid-type core, containing 9 and 21 viologen units in their branches, respectively, and terminated with tetraarylmethane derivatives. We have shown that, in dichlor
Publikováno v:
The Journal of Organic Chemistry. 67:9175-9181
A chemically addressable, bistable [2]rotaxane, which incorporates a dumbbell-shaped component containing both secondary dialkylammonium and 1,2-bis(pyridinium)ethane recognition sites for its ring component, dibenzo[24]crown-8 (DB24C8), has been ass
Publikováno v:
Organic Letters. 4:3565-3568
[reaction: see text] A dendrimer with rotaxane-like characteristics has been assembled under thermodynamic control from complementary wedge-shaped precursors by slippage in CH(2)Cl(2). The driving force for the self-assembly process is the molecular
Publikováno v:
Organic Letters. 4:679-682
[reaction: see text] A dendrimer wherein the branching points are mechanical in nature has been synthesized. It contains two identical covalently linked bis-dendrons and a core unit fused to two rings that encircle the two bis-dendrons. A "threading-
Publikováno v:
Collection of Czechoslovak Chemical Communications. 67:1719-1728
Five potential molecular shuttles based on degenerate [2]rotaxanes - wherein the ring component is a bis-1,4-phenylene[34]crown-10 and the dumbbell components are terminated by tetraarylmethane (slippage) stoppers and contain two identical bipyridini
Autor:
Daniel Skovronsky, Giorgio Attardo, Abhinay D. Joshi, Mark A. Mintun, Hartmuth C. Kolb, David Chien, Arkadij M. Elizarov, Carol A. Miller, Peter S. Conti
Publikováno v:
Alzheimer's & Dementia. 9
Autor:
Sergey Shcherbinin, William R. Shankle, Hartmuth C. Kolb, Mark A. Mintun, David Chien, Min-Ying Su, Arkadij M. Elizarov, Adam J. Schwarz, Michael J. Pontecorvo, Abhinay D. Joshi, Johannes Tauscher, Daniel Skovronsky
Publikováno v:
Alzheimer's & Dementia. 9