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of 8
pro vyhledávání: '"Arkadeep Sinha"'
Autor:
Kevin A Maupin, Arkadeep Sinha, Emily Eugster, Jeremy Miller, Julianna Ross, Vincent Paulino, Venkateshwar G Keshamouni, Nhan Tran, Michael Berens, Craig Webb, Brian B Haab
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e13002 (2010)
The ability to selectively detect and target cancer cells that have undergone an epithelial-mesenchymal transition (EMT) may lead to improved methods to treat cancers such as pancreatic cancer. The remodeling of cellular glycosylation previously has
Externí odkaz:
https://doaj.org/article/c76f04aba9cf4e68a2ab1fd0e4cfe094
Autor:
Kevin A. Short, Arkadeep Sinha, Tanu-Adhikari Niraula, Silvia Phillips-Salemka, Narayan Prasad Niraula
Publikováno v:
Journal of Industrial Microbiology and Biotechnology. 46:1217-1223
This is the first report of a fully annotated genomic sequence of Streptomyces spectabilis NRRL-2792, isolated and identified by The Upjohn Company in 1961. The genome was assembled into a single scaffold for annotation and analysis. The chromosome i
Autor:
Peter J. Allen, David Cherba, Jordan M. Winter, Randall E. Brand, Lorenzo F. Sempere, Brian B. Haab, Elliot Ensink, Galen Hostetter, Heather M. Calderone, Huiyuan Tang, Jessica Y. Sinha, Arkadeep Sinha
Publikováno v:
Analytical Chemistry. 87:9715-9721
Certain experiments involve the high-throughput quantification of image data, thus requiring algorithms for automation. A challenge in the development of such algorithms is to properly interpret signals over a broad range of image characteristics, wi
Autor:
Arkadeep Sinha, Elizabeth Lenkiewicz, Brian B. Haab, Lisa Evers, Heather Bartlam, Michael T. Barrett, David Cherba
Publikováno v:
Molecular Oncology. 8:1253-1265
The aggressiveness of pancreatic cancer is associated with the acquisition of mesenchymal characteristics by a subset of pancreatic cancer cells. The factors driving the development of this subset are not well understood. In this study, we tested the
Publikováno v:
Cancer Research. 75:A34-A34
Tumor associated macrophages (TAMs) are considered a critical component of the desmoplastic response, a variable host-tumor response and an ongoing research focus. Research and experimental plans have increased in complexity to better characterize th
Autor:
Arkadeep Sinha, Jordan M. Winter, Aprill Watanabe, Brian B. Haab, Peter J. Allen, Galen Hostetter
Publikováno v:
Cancer Research. 73:B60-B60
The poor outcome of pancreatic cancer is hypothesized to be due to a subset of cancer cells that have elevated propensity to metastasize and are resistant to current chemotherapeutics. In vitro, the process of epithelial to mesenchymal transition (EM
Publikováno v:
Cancer Research. 72:69-69
Pancreatic cancer cells that have mesenchymal traits can be particularly migratory and resistant to chemotherapeutics. These cells are presumed to represent a more advanced and deadly population of cells relative to cancer cells with more differentia
Autor:
Vincent M. Paulino, Venkat Keshamouni, Juli Ross, Jeremy A. Miller, Craig P. Webb, Nhan L. Tran, Kevin A. Maupin, Brian B. Haab, Arkadeep Sinha, Michael E. Berens
Publikováno v:
Cancer Research. 70:3311-3311
The lethal nature of pancreatic cancer is related to its propensity to disseminate at early stages and its resistance to chemotherapeutics. Cancer cells that have undergone epithelial-mesenchymal transition acquire these traits and may play an import