Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Arjuna, Singanayagam"'
Publikováno v:
Livers, Vol 3, Iss 2, Pp 240-257 (2023)
The peritoneum represents a confined microenvironment that has an emerging role as a distinct immunological compartment. In health, this niche is mainly populated by a heterogenous group of macrophages and T lymphocytes but also Natural Killer cells
Externí odkaz:
https://doaj.org/article/3184eda247a34fbfb4dcf8a08e7297f7
Autor:
Oltin-Tiberiu Pop, Anne Geng, Emilio Flint, Arjuna Singanayagam, Caner Ercan, Lucia Possamai, Vishal C. Patel, Patrizia Kuenzler, Marie-Anne Meier, Savas Soysal, Petr Hruz, Otto Kollmar, Kate C. Tatham, Josie K. Ward, Beat Müllhaupt, Achim Weber, Julia Wendon, Jan Hendrik Niess, Markus Heim, David Semela, Christopher Weston, Charalambos G. Antoniades, Luigi Maria Terracciano, Evangelos Triantafyllou, Robert G. Brenig, Christine Bernsmeier
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 1, Pp 17-37 (2023)
Background & Aims: AXL and MERTK expression on circulating monocytes modulated immune responses in patients with cirrhosis (CD14+HLA-DR+AXL+) and acute-on-chronic liver failure (CD14+MERTK+). AXL expression involved enhanced efferocytosis, sustained
Externí odkaz:
https://doaj.org/article/e232e5d8368941d4a69e17e66c9c9998
Autor:
Sofia Roth, Emilio Flint, Lea Ghataore, Vishal C. Patel, Arjuna Singanayagam, Royce P. Vincent, Evangelos Triantafyllou, Yun Ma, William Bernal, Georg Auzinger, Michael Heneghan, Charalambos Antoniades, Mirjam Christ-Crain, Mark J.W. McPhail, David R. Taylor, Julia Wendon, Christine Bernsmeier
Publikováno v:
Gastro Hep Advances, Vol 2, Iss 1, Pp 72-82 (2023)
Background and Aims: The clinical, prognostic, and therapeutic impact of adrenal insufficiency in acute liver failure (ALF) and acute-on-chronic liver failure (ACLF) remains controversial and exact diagnostic criteria are lacking. We sought to determ
Externí odkaz:
https://doaj.org/article/88eb0ec5b8d1477e8d7ccd3b1994e26e
Autor:
Fanny Lebossé, Cathrin Gudd, Enes Tunc, Arjuna Singanayagam, Rooshi Nathwani, Evangelos Triantafyllou, Oltin Pop, Naveenta Kumar, Sujit Mukherjee, Tie Zheng Hou, Alberto Quaglia, Fabien Zoulim, Julia Wendon, Ameet Dhar, Mark Thursz, Charalambos G. Antoniades, Wafa Khamri
Publikováno v:
EBioMedicine, Vol 49, Iss , Pp 258-268 (2019)
ABSTRACT: Background: Cirrhosis-associated immune dysfunction (CAID) contributes to high sepsis risk in patients with chronic liver disease. Various innate and; to a lesser extent; adaptive immune dysfunctions have been described as contributors to C
Externí odkaz:
https://doaj.org/article/081a539474c34548adf6b8413edd5c2e
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Chronic liver injury results in immune-driven progressive fibrosis, with risk of cirrhosis development and impact on morbidity and mortality. Persistent liver cell damage and death causes immune cell activation and inflammation. Patients with advance
Externí odkaz:
https://doaj.org/article/7110238c49634afda0b2a095007bbe1b
Publikováno v:
Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1398ef1866ca8473f186cea7fc3fbff
https://doi.org/10.1136/gutjnl-2022-basl.57
https://doi.org/10.1136/gutjnl-2022-basl.57
Autor:
Gioia Bratos, William Ovenden, Sarah Clark, Daniel Forton, Sarah Hughes, Arjuna Singanayagam, Metin Yalcin
Publikováno v:
Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76f20555067441f48e876b57ae5224ed
https://doi.org/10.1136/gutjnl-2022-basl.100
https://doi.org/10.1136/gutjnl-2022-basl.100
Publikováno v:
Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80143193a1d66efc2d746f05dcbfc0b8
https://doi.org/10.1136/gutjnl-2022-basl.21
https://doi.org/10.1136/gutjnl-2022-basl.21
Publikováno v:
Clin Med (Lond)
Cirrhosis is associated with intestinal dysbiosis, with specific alterations in the gut microbiota linked to particular aetiologies and manifestations of the disease. We review the role of the gut microbiome and the importance of the intestinal barri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::500d8d2471c65c27632df5322db460d2
https://doi.org/10.7861/clinmed.2020-0676
https://doi.org/10.7861/clinmed.2020-0676
Autor:
Sujit Mukherjee, Evangelos Triantafyllou, Oltin T Pop, Fabien Zoulim, Enes Tunc, Alberto Quaglia, Arjuna Singanayagam, Wafa Khamri, Mark Thursz, Tie Zheng Hou, Fanny Lebossé, Julia Wendon, Rooshi Nathwani, Charalambos G. Antoniades, Cathrin Gudd, Naveenta Kumar, A. Dhar
Publikováno v:
EBioMedicine
EBioMedicine, 2019, 49, pp.258-268. ⟨10.1016/j.ebiom.2019.10.011⟩
EBioMedicine, 2019, 49, pp.258-268. ⟨10.1016/j.ebiom.2019.10.011⟩
Background Cirrhosis-associated immune dysfunction (CAID) contributes to high sepsis risk in patients with chronic liver disease. Various innate and; to a lesser extent; adaptive immune dysfunctions have been described as contributors to CAID leading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9318081e284f95b31ce34f205764d8db
http://europepmc.org/articles/PMC6945243
http://europepmc.org/articles/PMC6945243