Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Arjun Khunger"'
Publikováno v:
The Egyptian Heart Journal, Vol 74, Iss 1, Pp 1-8 (2022)
Abstract Background Takotsubo cardiomyopathy (TCM) is a non-ischemic syndrome characterized by transient acute left ventricular dysfunction as evident on transthoracic echocardiography. It can often mimic myocardial ischemia and is characterized by t
Externí odkaz:
https://doaj.org/article/c8d6193de95d4982ab35fd990d791b78
Publikováno v:
Infectious Disease Reports, Vol 14, Iss 3, Pp 446-452 (2022)
Coronavirus disease 2019 (COVID-19) and tuberculosis (TB) are currently the two leading causes of death among infectious diseases. As we progress towards a “new normal”, more information is required regarding post-COVID-19 syndromes. We present a
Externí odkaz:
https://doaj.org/article/b3be1d4c35164cb7ba203fa4e513c4ef
Autor:
Edward J Spangenthal, Igor Puzanov, Marc S Ernstoff, Pankit Vachhani, Fumito Ito, Ankita Kapoor, Benjamin Switzer, Poornima Subramanian, Yan V Yatsynovich, David M Jacobs, Maya R Chilbert, Umesh C Sharma, Steven G Feuerstein, Filip Stefanovic, Mark D Hicar, Anne B Curtis, Grace K Dy, Brian J Page, Nikhil Agrawal, Arjun Khunger, Alexander Hattoum, Jerome J Schentag
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background Immune checkpoint inhibitors (ICI) have emerged as a front-line therapy for a variety of solid tumors. With the widespread use of these agents, immune-associated toxicities are increasingly being recognized, including fatal myocarditis. Th
Externí odkaz:
https://doaj.org/article/26e58c0f16aa4f4d82e356fda713f180
Autor:
Nikhil Agrawal, Arjun Khunger, Pankit Vachhani, Teresa A. Colvin, Alexander Hattoum, Edward Spangenthal, Anne B. Curtis, Grace K. Dy, Marc S. Ernstoff, Igor Puzanov
Publikováno v:
Case Reports in Oncology, Vol 12, Iss 1, Pp 260-276 (2019)
The development of immune checkpoint inhibitors (ICIs) has revolutionized the treatment of patients with advanced stage cancers. However, immune-related adverse events are frequently observed. Cardiac toxicity from ICI therapy can range from asymptom
Externí odkaz:
https://doaj.org/article/050b36a63cac4605ad2f222a88150cca
Autor:
Arjun Khunger, Ghanashyam Sarikonda, Jennifer Tsau, Anil Pahuja, Zeni Alfonso, Jane Gao, Christian Laing, Christine Vaupel, Naveen Dakappagari, Ahmad A. Tarhini
Publikováno v:
Translational Oncology, Vol 14, Iss 3, Pp 101014- (2021)
Neoadjuvant therapy with ipilimumab in combination with high dose IFNα was evaluated in patients with locally/regionally advanced melanoma in a previously reported clinical trial [NCT01608594]. In this study, peripheral immune cell profiling was per
Externí odkaz:
https://doaj.org/article/099a2088a9b64bcebb0642fdaabb7971
Autor:
Arjun Khunger, Erin Piazza, Sarah Warren, Thomas H Smith, Xing Ren, Andrew White, Nathan Elliott, Alessandra Cesano, Joseph M Beechem, John M Kirkwood, Ahmad A Tarhini
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0245287 (2021)
Patients with locally/regionally advanced melanoma were treated with neoadjuvant combination immunotherapy with high-dose interferon α-2b (HDI) and ipilimumab in a phase I clinical trial. Tumor specimens were obtained prior to the initiation of neoa
Externí odkaz:
https://doaj.org/article/f7345cfe4dac4613b0bb7a5b6e8e8a42
Publikováno v:
OncoImmunology, Vol 8, Iss 11 (2019)
Patients with metastatic melanoma were treated with tremelimumab and interferon-α (IFN) in a previously reported clinical trial [NCT00610857]. Responses were assessed by RECIST criteria as complete (CR) or partial (PR), stable disease (SD) or progre
Externí odkaz:
https://doaj.org/article/f6efe622c88449a387f3ba2729e5d317
Autor:
Arjun Khunger, Zachary S. Buchwald, Michael Lowe, Mohammad K. Khan, Keith A. Delman, Ahmad A. Tarhini
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 11 (2019)
Locally/regionally advanced melanoma confers a major challenge in terms of surgical and medical management. Surgical treatment carries the risks of surgical morbidities and potential complications that could be lasting. In addition, these patients co
Externí odkaz:
https://doaj.org/article/bf8634c2cd224b56b0f09af78e3cd381
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 12 (2018)
Mutations in the BRAF oncogene are found in 2–4% of all non-small cell lung cancer (NSCLC) patients. The most common activating mutation present within the BRAF oncogene is associated with valine substitution for glutamate at position 600 (V600E) w
Externí odkaz:
https://doaj.org/article/2623d8b8aaee404d9df600a4c77d4bfd
Autor:
Monica Khunger, Pradnya Dinkar Patil, Arjun Khunger, Manshi Li, Bo Hu, Sagar Rakshit, Arnab Basu, Nathan Pennell, James P Stevenson, Paul Elson, Tanmay S Panchabhai, Vamsidhar Velcheti
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0197743 (2018)
BACKGROUND:The absolute neutrophil count (ANC), absolute lymphocyte count (ALC), absolute monocyte count (AMC) and neutrophil to lymphocyte ratio (NLR) are known markers of inflammation. We evaluated whether ANC, ALC, AMC and NLR, both before and aft
Externí odkaz:
https://doaj.org/article/04172441db5248ef9a0d4dcd3d834d52