Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Arjun Guha"'
Autor:
Sai Manoz Lingamallu, Aditya Deshpande, Neenu Joy, Kirthana Ganeshan, Neelanjana Ray, Rajesh Kumar Ladher, Makoto Mark Taketo, Daniel Lafkas, Arjun Guha
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114654- (2024)
Summary: Lower airway club cells (CCs) serve the dual roles of a secretory cell and a stem cell. Here, we probe how the CC fate is regulated. We find that, in response to acute perturbation of Notch signaling, CCs adopt distinct fates. Although the v
Externí odkaz:
https://doaj.org/article/2b55afce4f3340aaa72f2ecf3cc86a40
Autor:
Amrutha Kizhedathu, Piyush Chhajed, Lahari Yeramala, Deblina Sain Basu, Tina Mukherjee, Kutti R Vinothkumar, Arjun Guha
Publikováno v:
eLife, Vol 10 (2021)
Progenitors of the thoracic tracheal system of adult Drosophila (tracheoblasts) arrest in G2 during larval life and rekindle a mitotic program subsequently. G2 arrest is dependent on ataxia telangiectasia mutated and rad3-related kinase (ATR)-depende
Externí odkaz:
https://doaj.org/article/c6a6fa25a40c4c62b5490fb4d24957bd
Autor:
Chaitra Prabhakara, Rashmi Godbole, Parijat Sil, Sowmya Jahnavi, Shah-E-Jahan Gulzar, Thomas S van Zanten, Dhruv Sheth, Neeraja Subhash, Anchal Chandra, Akshatha Shivaraj, Patricia Panikulam, Ibrahim U, Vijay Kumar Nuthakki, Theja Parassini Puthiyapurayil, Riyaz Ahmed, Ashaq Hussain Najar, Sai Manoz Lingamallu, Snigdhadev Das, Bhagyashri Mahajan, Praveen Vemula, Sandip B Bharate, Parvinder Pal Singh, Ram Vishwakarma, Arjun Guha, Varadharajan Sundaramurthy, Satyajit Mayor
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009706 (2021)
Many viruses utilize the host endo-lysosomal network for infection. Tracing the endocytic itinerary of SARS-CoV-2 can provide insights into viral trafficking and aid in designing new therapeutic strategies. Here, we demonstrate that the receptor bind
Externí odkaz:
https://doaj.org/article/0a514d6b699d4c4997dd0bfe6c9b9ffe
Publikováno v:
eLife, Vol 9 (2020)
Larval tracheae of Drosophila harbour progenitors of the adult tracheal system (tracheoblasts). Thoracic tracheoblasts are arrested in the G2 phase of the cell cycle in an ATR (mei-41)-Checkpoint Kinase1 (grapes, Chk1) dependent manner prior to mitot
Externí odkaz:
https://doaj.org/article/7e3c089b5c734fef87795d62bb367fc7
Publikováno v:
Cell Reports, Vol 19, Iss 2, Pp 246-254 (2017)
Summary: There is evidence that certain club cells (CCs) in the murine airways associated with neuroepithelial bodies (NEBs) and terminal bronchioles are resistant to the xenobiotic naphthalene (Nap) and repopulate the airways after Nap injury. The i
Externí odkaz:
https://doaj.org/article/fb39119202834e13916bce6664544d11
Publikováno v:
eLife, Vol 7 (2018)
Imaginal progenitors in Drosophila are known to arrest in G2 during larval stages and proliferate thereafter. Here we investigate the mechanism and implications of G2 arrest in progenitors of the adult thoracic tracheal epithelium (tracheoblasts). We
Externí odkaz:
https://doaj.org/article/777d6731a382485ebe72c904c2fbe6e2
Publikováno v:
eLife, Vol 4 (2015)
The Drosophila tracheal system is a branched tubular network that forms in the embryo by a post-mitotic program of morphogenesis. In third instar larvae (L3), cells constituting the second tracheal metamere (Tr2) reenter the cell cycle. Clonal analys
Externí odkaz:
https://doaj.org/article/adafd2ff5a5d4077b5d6bf821dc1c5c6
Autor:
Arjun Guha, Michelle Vasconcelos, Rui Zhao, Adam C Gower, Jayaraj Rajagopal, Wellington V Cardoso
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88848 (2014)
Clara cells (CCs) are a morphologically and operationally heterogeneous population of Secretoglobin Scgb1a1-expressing secretory cells that are crucial for airway homeostasis and post-injury repair. Analysis of the extent and origin of CC diversity a
Externí odkaz:
https://doaj.org/article/c5acb077ee6d43ad83b40c6aa2ae7036
Autor:
Federico Cassano, John Gouwar, Daniel Nguyen, Sydney Nguyen, Luna Phipps-Costin, Donald Pinckney, Ming-Ho Yee, Yangtian Zi, Carolyn Jane Anderson, Molly Q Feldman, Arjun Guha, Michael Greenberg, Abhinav Jangda
Publikováno v:
IEEE Transactions on Software Engineering. :1-17
Publikováno v:
2023 IEEE International Conference on Software Testing, Verification and Validation Workshops (ICSTW).