Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Arjun Bollampalli"'
Autor:
Sivan Elloul, Anne-Sophie Dugast, Shannon McArdel, Enping Hong, Arjun Bollampalli, Maegan Hoover, Sneha Pawar, Viral Amin, Kangjian Qiao, Christopher Ta, Laurence Turka, Thomas Wickham
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/8a6fd99397684961baede2a785881b1e
Autor:
Shannon C. Leonard, Maegan Hoover, Thomas Wickham, Shannon McArdel, Sivan Elloul, Laurence A. Turka, Arjun Bollampalli, Zafira Castaño, Nicholas Bayhi, Christopher L. Carpenter, Enping Hong, Douglas C. McLaughlin, Kelvin Muriuki, Sneha Pawar, Jennifer Mellen, Anne-Sophie Dugast
Publikováno v:
Cancer Immunology, Immunotherapy
Recombinant agonists that activate co-stimulatory and cytokine receptors have shown limited clinical anticancer utility, potentially due to narrow therapeutic windows, the need for coordinated activation of co-stimulatory and cytokine pathways and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbe885a6cd179d218e17e1b066a9ffe
https://pubmed.ncbi.nlm.nih.gov/34244816
https://pubmed.ncbi.nlm.nih.gov/34244816
Autor:
Anne-Sophie Dugast, Maegan Hoover, Sivan Elloul, Christopher Ta, Shannon McArdel, Kangjian Qiao, Arjun Bollampalli, Sneha Pawar, Enping Hong, Laurence A. Turka, Thomas Wickham, Viral Amin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Agonist antibodies and recombinant cytokines have had limited success in the clinic due to three factors: severe toxicity leading to a narrow therapeutic index, the diminished activity of an agonistic antibody compared with natural ligand,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793b2af000a78135365c87e60e09a2c3
https://doaj.org/article/8a6fd99397684961baede2a785881b1e
https://doaj.org/article/8a6fd99397684961baede2a785881b1e
Autor:
Sivan Elloul, Anne-Sophie Dugast, Shannon McArdel, Ryan Pepi, Maegan Hoover, Laurence A. Turka, Enping Hong, Alex Nanna, Shannon C. Leonard, Arjun Bollampalli, Zafira Castaño
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundAgonist antibodies and recombinant cytokines have had limited success in the clinic due to three factors: severe toxicity leading to a narrow therapeutic index, the diminished activity of an agonistic antibody compared with natural ligand,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe071823ce9853501c1166ccac4b625
https://doi.org/10.1136/jitc-2021-sitc2021.208
https://doi.org/10.1136/jitc-2021-sitc2021.208
Autor:
Anne-Sophie Dugast, Enping Hong, Maegan Hoover, Arjun Bollampalli, Douglas C. McLaughlin, Omkar Bhate, Timothy J. Lyford, Torben Straight Nissen, Christopher L. Carpenter, Thomas J. Wickham, Sivan Elloul
Publikováno v:
Cancer Research. 79:3256-3256
Recombinant IL-12 is a potent cytokine that has held significant promise as an immunotherapeutic. In preclinical studies, recombinant IL-12 has impressive anti-tumor activity; however toxicity and a narrow therapeutic window halted development in hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b22f405d617a0e68ea13cd287d2540b
https://doi.org/10.1158/1538-7445.am2019-3256
https://doi.org/10.1158/1538-7445.am2019-3256
Autor:
Thomas Wickham, Jennifer Mellen, Shannon McArdel, Enping Hong, Maegan Hoover, Sivan Elloul, Torben Straight Nissen, Anne-Sophie Dugast, Douglas C. McLaughlin, Shannon C. Leonard, Christopher L. Carpenter, Arjun Bollampalli
Publikováno v:
Cancer Research. 79:3272-3272
Recombinant agonists that activate co-stimulatory and cytokine receptors have shown limited clinical activity perhaps due to 1) toxicity; 2) a need for coordinated activation of co-stimulatory and cytokine pathways; or 3) the failure of agonist antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1f3863c0ab3c68b0f1acedafbde673d
https://doi.org/10.1158/1538-7445.am2019-3272
https://doi.org/10.1158/1538-7445.am2019-3272
Autor:
McArdel, Shannon L., Dugast, Anne-Sophie, Hoover, Maegan E., Bollampalli, Arjun, Hong, Enping, Castano, Zafira, Leonard, Shannon Curtis, Pawar, Sneha, Mellen, Jennifer, Muriuki, Kelvin, McLaughlin, Douglas C., Bayhi, Nicholas, Carpenter, Christopher L., Turka, Laurence A., Wickham, Thomas J., Elloul, Sivan
Publikováno v:
Cancer Immunology, Immunotherapy; Sep2021, Vol. 70 Issue 9, p2701-2719, 19p
Autor:
Root, Adam R., Guntas, Gurkan, Katragadda, Madan, Apgar, James R., Narula, Jatin, Chang, Chew Shun, Hanscom, Sara, McKenna, Matthew, Wade, Jason, Meade, Caryl, Ma, Weijun, Guo, Yongjing, Liu, Yan, Duan, Weili, Hendershot, Claire, King, Amy C., Zhang, Yan, Sousa, Eric, Tam, Amy, Benard, Susan
Publikováno v:
mAbs; Jan-Dec 2021, Vol. 13 Issue 1, p1-18, 18p