Zobrazeno 1 - 10
of 348
pro vyhledávání: '"Arjan W Griffioen"'
Autor:
Peter A Jarzyna, Lisette H Deddens, Benjamin H Kann, Sarayu Ramachandran, Claudia Calcagno, Wei Chen, Anita Gianella, Rick M Dijkhuizen, Arjan W Griffioen, Zahi A Fayad, Willem JM Mulder
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 10, Pp 964-973 (2012)
One of the challenges of tailored antiangiogenic therapy is the ability to adequately monitor the angiogenic activity of a malignancy in response to treatment. The αvβ3 integrin, highly overexpressed on newly formed tumor vessels, has been successf
Externí odkaz:
https://doaj.org/article/7b7aaad2844948b8a83dfaa226b8eb69
Autor:
Iris A Schulkens, Roy Heusschen, Vivian van den Boogaart, Robert-Jan van Suylen, Anne-Marie C Dingemans, Arjan W Griffioen, Victor L Thijssen
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107988 (2014)
Approximately 30-40% of the patients with early stage non-small cell lung cancer (NSCLC) will present with recurrent disease within two years of resection. Here, we performed extensive galectin expression profiling in a retrospective study using froz
Externí odkaz:
https://doaj.org/article/67e46d41674a4581ba2c9e7c25de27bb
Autor:
Battuja Dugershaw‐Kurzer, Jonas Bossart, Marija Buljan, Yvette Hannig, Sarah Zehnder, Govind Gupta, Vera M. Kissling, Patrycja Nowak‐Sliwinska, Judy R. vanBeijnum, Arjan W. Griffioen, Stefan Masjosthusmann, Etta Zühr, Ellen Fritsche, René Hornung, Thomas Rduch, Tina Buerki‐Thurnherr
Publikováno v:
Advanced Science, Vol 11, Iss 28, Pp n/a-n/a (2024)
Abstract Exposure to nanoparticles (NPs) in pregnancy is increasingly linked to adverse effects on embryo‐fetal development and health later in life. However, the developmental toxicity mechanisms of NPs are largely unknown, in particular potential
Externí odkaz:
https://doaj.org/article/2a31beb452ae480abf4e8493d6d513f5
Autor:
Mafalda Antunes-Ferreira, Silvia D’Ambrosi, Mohammad Arkani, Edward Post, Sjors G. J. G. In ‘t Veld, Jip Ramaker, Kenn Zwaan, Ece Demirel Kucukguzel, Laurine E. Wedekind, Arjan W. Griffioen, Mirjam Oude Egbrink, Marijke J. E. Kuijpers, Daan van den Broek, David P. Noske, Koen J. Hartemink, Siamack Sabrkhany, Idris Bahce, Nik Sol, Harm-Jan Bogaard, Danijela Koppers-Lalic, Myron G. Best, Thomas Wurdinger
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Liquid biopsy approaches offer a promising technology for early and minimally invasive cancer detection. Tumor-educated platelets (TEPs) have emerged as a promising liquid biopsy biosource for the detection of various cancer types. In this s
Externí odkaz:
https://doaj.org/article/9358e61d08a441cdb79204397fabd108
Autor:
Siamack Sabrkhany, Marijke J.E. Kuijpers, Sander M.J. van Kuijk, Arjan W. Griffioen, Mirjam G.A. oude Egbrink
Publikováno v:
Haematologica, Vol 108, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/bd013716a69b4ea7864b206ff17cc434
Autor:
Athanasios Blanas, Haiko Karsjens, Aafke de Ligt, Elisabeth J.M. Huijbers, Karlijn van Loon, Stepan S. Denisov, Canan Durukan, Diederik J.M. Engbersen, Jan Groen, Sven Hennig, Tilman M. Hackeng, Judy R. van Beijnum, Arjan W. Griffioen
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104719- (2022)
Summary: Poor immunogenicity of critical epitopes can hamper vaccine efficacy. To boost immune recognition of non- or low-immunogenic antigens, we developed a vaccine platform based on the conjugation of a target protein to a chimeric designer peptid
Externí odkaz:
https://doaj.org/article/1255ada1fb7443d9a31a721694925fe9
Autor:
Marloes Zoetemelk, George M. Ramzy, Magdalena Rausch, Thibaud Koessler, Judy R. vanBeijnum, Andrea Weiss, Valentin Mieville, Sander R. Piersma, Richard R. deHaas, Céline Delucinge‐Vivier, Axel Andres, Christian Toso, Alexander A. Henneman, Simone Ragusa, Tatiana V. Petrova, Mylène Docquier, Thomas A. McKee, Connie R. Jimenez, Youssef Daali, Arjan W. Griffioen, Laura Rubbia‐Brandt, Pierre‐Yves Dietrich, Patrycja Nowak‐Sliwinska
Publikováno v:
Molecular Oncology, Vol 14, Iss 11, Pp 2894-2919 (2020)
The current standard of care for colorectal cancer (CRC) is a combination of chemotherapeutics, often supplemented with targeted biological drugs. An urgent need exists for improved drug efficacy and minimized side effects, especially at late‐stage
Externí odkaz:
https://doaj.org/article/95a558b6cae1422989a521f96cb74001
Publikováno v:
Research and Clinical Medicine, Vol I, Iss 1, Pp 9-13 (2016)
It is generally understood that improvement of cancer therapies is achieved by the combination of drugs. This approach will improve efficacy, while toxicity and the risk for drug resistance may be decreased. In this review, the efforts on combining
Externí odkaz:
https://doaj.org/article/180bb10d879a47739eac4e1d05a037d4
Autor:
Henk M.W. Verheul, Godefridus J. Peters, Roberto Pili, Yehuda G. Assaraf, Arjan W. Griffioen, Gerrit Jansen, René J. Musters, Laurens V. Beerepoot, Michelle A. Rudek, Richard J. Honeywell, Henk Dekker, Richard R. de Haas, Mariette Labots, Henk J. Broxterman, Kristy J. Gotink
PDF file - 174K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5840a1a52a6a55d2e5d2dd26046267c0
https://doi.org/10.1158/1078-0432.22443194
https://doi.org/10.1158/1078-0432.22443194
Autor:
Kevin H. Mayo, Arjan W. Griffioen, Michael A. Farrar, Matthew F. Mescher, Mirjam G.A. oude Egbrink, Yan Zhang, Flavia Popescu, Karolien Castermans, Kieng B. Vang, Ruud P.M. Dings
Purpose: Tumor-released proangiogenic factors suppress endothelial adhesion molecule (EAM) expression and prevent leukocyte extravasation into the tumor. This is one reason why immunotherapy has met with limited success in the clinic. We hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1897464c422f968fc410e1ee79855db8
https://doi.org/10.1158/1078-0432.c.6518661.v1
https://doi.org/10.1158/1078-0432.c.6518661.v1